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Presentation of a protein antigen to T cells generally requires that the antigen be enzymatically processed into an immunogenic peptide(s). The identification of a protease(s) and its mechanism of action in the proteolysis of such an antigen is therefore a primary goal in the study of antigen processing. We show here that Insulin degrading enzyme (IDE), a neutral thiol metalloendo-proteinase that
Almost all countries in the world are party to the Rio Conventions. This entails a number of responsibilities, including reporting periodically on aspects of environmental health and national implementation of the convention. These reports can cover hundreds of pages, so completing reports is often a significant undertaking. Since countries can be party to numerous Multilateral Environmental Agree
BACKGROUND: Summary measures of health are essential in making estimates of health status that are comparable across time and place. They can be used for assessing the performance of health systems, informing effective policy making, and monitoring the progress of nations toward achievement of sustainable development goals. The Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD
INTRODUCTION: Whether low socioeconomic status (SES) is associated with worse rheumatoid arthritis (RA) outcomes in countries with general tax-financed healthcare systems (such as Sweden) remains to be elucidated. Our aim was to investigate the influence of educational background (achieving university/college degree (high) or not (low)) on the outcomes of early RA, in terms of disease activity (DA
Several extensions of the standard model predict associated production of dark-matter particles with a Higgs boson. Such processes are searched for in final states with missing transverse momentum and a Higgs boson decaying to a bb pair with the ATLAS detector using 36.1 fb-1 of pp collisions at a center-of-mass energy of 13 TeV at the LHC. The observed data are in agreement with the standard mode
The endogenous reparative capacity of the adult human brain is low, and chronic neurodegenerative disorders of the central nervous system represent one of the greatest areas of unmet clinical need in the developing world. Novel therapeutic strategies to treat them include: (i) growth factor delivery to boost endogenous repair and (ii) replacement cell therapy, including replacing dopaminergic neur
Summary: Osteoporotic fractures may pose a challenge for skeletal regeneration. This study investigates if pharmaceutical interventions such as bone morphogenetic protein 7 (BMP-7) alone or in combination with Zoledronate have equivalent efficacy in osteoporotic bone? Our findings suggest they do and that an osteoporotic bone environment may increase sensitivity to BMP-7. Introduction: Osteoporosi
HEIMDAL will be a multi length scale neutron scattering instrument for the study of structures covering almost nine orders of magnitude from 0.01 nm to 50 mm. The instrument is accepted for construction at the European Spallation Source (ESS) and features a variable resolution thermal neutron powder diffractometer (TNPD), combined with small angle neutron scattering (SANS) and neutron imaging (NI)
In the licentiate thesis, it is researched and analyzed how sustainability criteria may be used in a legal framework, with the purpose to promote and safeguard sustainable products and their production. The research and analysis are conducted on the basis of the EU approach to use sustainability criteria for biofuels in the transport sector, legally expressed in Directive 2009/28/EC, and its amend
Researchers and teachers often recommend motivating exercises and use of mathematics or statistics software for the teaching of basic courses in probability and statistics. Our courses are given to large groups of engineering students at Lund Institute of Technology. We found that the mere existence of real-life data and technology in a course does not automatically increase students’ motivation o
A search for supersymmetry in events with large missing transverse momentum, jets, and at least one hadronically decaying τ-lepton is presented. Two exclusive final states with either exactly one or at least two τ-leptons are considered. The analysis is based on proton-proton collisions at s=13 TeV corresponding to an integrated luminosity of 36.1 fb-1 delivered by the Large Hadron Collider and re
A search for heavy right-handed Majorana or Dirac neutrinos N R and heavy right-handed gauge bosons W R is performed in events with a pair of energetic electrons or muons, with the same or opposite electric charge, and two energetic jets. The events are selected from pp collision data with an integrated luminosity of 36.1 fb −1 collected by the ATLAS detector at s=13 TeV. No significant deviations
Large, comprehensive studies of the risk for neurologic disorders among long-term survivors of noncentral nervous system (CNS) childhood cancers are lacking. Thus, the aim of our study was to assess the lifetime risk of Nordic non-CNS childhood cancer survivors for neurologic disorders. We identified 15,967 5-year survivors of non-CNS childhood cancer diagnosed in Denmark, Iceland, Finland and Swe
Theoretical calculations of reaction kinetics were done for one‐step reactions catalyzed by cells immobilized in spherical beads. The reactions catalyzed by free cells were assumed to obey Michaelis–Menten kinetics for a one‐substrate reaction. Both external (outside the beads) and internal (inside the beads) mass transfer of the substrate were considered for the immobilized preparations. The theo
Searches for the electroweak production of charginos, neutralinos and sleptons in final states characterized by the presence of two leptons (electrons and muons) and missing transverse momentum are performed using 20.3 fb(-1) of proton-proton collision data at root s = 8 TeV recorded with the ATLAS experiment at the Large Hadron Collider. No significant excess beyond Standard Model expectations is
Program 180 högskolepoäng | 3 år | Kandidatexamen Ett kandidatprogram innebär tre års heltidsstudier. Vi har fyra inriktningar på vårt kandidatprogram: fysik, teoretisk fysik, astronomi och astrofysik samt kemi/fysik. Alla inriktningar leder fram till en naturvetenskaplig kandidatexamen. Som student antagen till kandidatprogrammet i fysik läser du kurser på grundläggande och avancerad nivå i sex t
https://www.fysik.lu.se/utbildning/kandidatprogram - 2026-06-23
Sedan 2024 finns en kamerafälla i Botaniska trädgården som ska hitta invasiva främmande nattfjärilsarter. Fällan sattes upp av forskare på Lunds universitet och är en del i en europeisk tvåårig pilotstudie som testar system för att övervaka den biologiska mångfalden. Europeiskt samarbete kring invasiva arterEn av de främsta orsakerna till förlust av biologisk mångfald är invasiva främmande arter.
https://www.botan.lu.se/inventering-av-invasiva-frammande-nattfjarilar - 2026-06-23
