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More than 90% of DNA does not code for proteins and for a long time these sequences were referred to as “junk DNA” due to their unknown purpose. With the advent of new technologies it is now known, that the non-coding part of the genome is of great importance for regulating gene expression and is therefore indispensable. Transposable elements comprise about 50% of the genome and co-exist as symbio

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Three recent randomised trials have shown a lack of effect of EGDT for the treatment of severe sepsis and septic shock. Notably, control group care was excellent in all trials, including early recognition, early and aggressive fluid resuscitation and prompt administration of antibiotics, and was reflected in a lower than expected mortality.The discussion emphasizes the need for continued vigilance

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This article offers narratives of individual journeys through the scholarship of leading in three different contexts—Asia, Europe, and Africa. Together, these narratives argue for the need to make explicit the diversity of practices of the scholarship of teaching and learning (SoTL), with each practice inextricably tied to specific geographical, sociocultural, and political contexts. In offering t

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This paper tests the “Square Root Rule” (the SRR), a Basel sanctioned method of scaling 1-day Value At risk to higher time horizons. The SRR has come under serious assault from leading researchers focusing on its week theoretical basis: assuming i.i.d. asset returns. I performed an empirical test of the SRR on the 10-day horizon, the maximum horizon allowed by Basel, comparing SRR performance to d

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This paper critically analyses European Court of Human Rights jurisprudence on bulk data collection, situating it within the Court’s broader turn to proceduralism. We argue that, in cases concerning mass surveillance, the Court has effectively abandoned structured proportionality review and transformed national security from a prima facie legitimate aim into a de facto exception to Article 8. Plac

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From the end of the nineteenth century and one hundred years onward, home sewing was an important part of many women’s duties, but it was also a pleasure, something that existed parallel with the emerging mass-produced ready-to-wear industry. The paper patterns used for home dressmaking were often sold and distributed through women’s magazines. These pattern sections were both a kind of reader ser

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This book is about projectification – a concept that captures the increasing reliance on “the project” in contemporary societies, governance and economies. Despite its significance, this development and transformation, not only of public and private organizations but also our working environment and way of living, has received little scholarly attention compared to other major societal movements.

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In this concluding chapter, the editors take a step back, zoom out and reflect upon the significance of theoretical developments presented and what empirical implications this knowledge may have. In addition to discussing the state of this emerging research field of projectification, the chapter also opens up for further research and invites scholars from different fields of research and with diff

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Using judges and stage actors as instructive polar types this article elucidates factors that influence the inclination to empathise. Both come in close contact with dramatic life stories on an everyday basis but approach empathy from contrasting vantage points: emotional distance versus emotional engagement. Similarities between these polar types can thus disentangle some of the factors that inflUsing judges and stage actors as instructive polar types this article elucidates factors that influence the inclination to empathise. Both come in close contact with dramatic life stories on an everyday basis but approach empathy from contrasting vantage points: emotional distance versus emotional engagement. Similarities between these polar types can thus disentangle some of the factors that infl

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Among the more than 2,000 interments from the Phaleron Burial Ground, 79 individuals buried in the Esplanada mass graves are said to have died violently, perhaps bludgeoned to death. The Esplanada remains were observed in the field by Ingvarsson and Bäckström (2019); ten of these 79 were later excavated and studied by Buikstra and colleagues in a laboratory setting. The field and laboratory analysAmong the more than 2,000 interments from the Phaleron Burial Ground, 79 individuals buried in the Esplanada mass graves are said to have died violently, perhaps bludgeoned to death. The Esplanada remains were observed in the field by Ingvarsson and Bäckström (2019); ten of these 79 were later excavated and studied by Buikstra and colleagues in a laboratory setting. The field and laboratory analys

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Skeletal muscle capillary density is correlated with physical performance and whole-body metabolic properties. Thus, we performed a genome-wide association study of skeletal muscle capillary-to-fiber ratio (C:F) (n = 603 males) and found that the rs115660502 G allele was associated (p < 5 × 10 -8) with increased C:F and reduced skeletal muscle expression of RAB3 GTPase-activating non-catalytic p

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Light/dark cycles play an essential role in people's performance, mood and daily rhythm. This study aimed to evaluate an early prototype of a personalised home lighting system including body-worn loggers. A convenience sample (N = 28) wore the devices for 23 h in the field and were given a demonstration of the lighting system components. Participants reported on questionnaires their acceptance of

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The HAVOSS (Handling Vulnerabilities in OSS) maturity model describes important processes for managing security vulnerabilities in OSS modules in developed products. So far, the model has not been evaluated in any real assessment process. Here we present a study where the model was evaluated by using it in assessments of processes for two product types in one organization. Each assessment was cond

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Henzinger et al. posed the so-called Online Boolean Matrix-vector Multiplication (OMv) conjecture and showed that it implies tight hardness results for several basic dynamic or partially dynamic problems [STOC'15]. We first show that the OMv conjecture is implied by a simple off-line conjecture that we call the MvP conjecture. We then show that if the definition of the OMv conjecture is generalize

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True Partnership as True Learning is ultimately a book about satisfaction. It is a book about working at, and being part of the Swedish law firm Mannheimer Swartling. More specifically, it is a book about knowledge sharing. The aim of this book is to outline a discussion on how, and why, knowledge is shared in practice, and what it takes to achieve an elite identity organization and sustainable surue Partnership as True Learning is ultimately a book about satisfaction. It is a book about working at, and being part of the Swedish law firm Mannheimer Swartling. More specifically, it is a book about knowledge sharing.The aim of this book is to outline a discussion on how, and why, knowledge is shared in practice, and what it takes to achieve an elite identity organization and sustainable succ

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In Swedish law, the notion of ‘science and proven experience’ (in Swedish, vetenskap och beprövad erfarenhet) defines the gold standard for public decision-making and practice, especially in medicine. The notion is notoriously vague but nevertheless plays an important role in the distribution of rights and duties of patients and healthcare workers. For example, failure to provide care in accordanc

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Forest ecosystems, covering over a third of land on the Earth, play a significant role in the global hydrological cycle, and influence soil erosion and climate change. However, the distribution, movements, quality of water, and hydrological processes in forested ecosystems are not well understood yet. This thesis aims to improve our understanding of the interaction between forest ecosystems and waForest ecosystems, covering over a third of land on the Earth, play a significant role in the global hydrological cycle, and influence soil erosion and climate change. However, the distribution, movements, quality of water, and hydrological processes in forested ecosystems are not well understood yet. This thesis aims to improve our understanding of the interaction between forest ecosystems and wa

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Apprenticeship training is a form of education that arouses a great deal of interest as regards the challenges that characterise conditions for young people on the current labour market. This is obvious both in Sweden and in other comparable countries. This chapter begin by illustrating the changed conditions for establishment of young people, a factor that may help to enhance understanding of why

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3D pose estimation is a crucial element for enabling robots to work in industrial environment to perform tasks like bin-picking or depalletizing. Even though there exist various pose estimation algorithms, they usually deal with common daily objects applied in lab environments. However, coping with real-world industrial objects is a much harder challenge for most pose estimation techniques due to

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Atmospheric models are used both to assist in the retrieval of information about tropospheric composition and to interpret the results. The models themselves encompass much of our knowledge and understanding about trace components in the atmosphere and so they themselves must be tested against data. Care must be taken not to mix the dual role so that one can be sure of the conclusions drawn, and a