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Lung transplantion (LTx) recipients have low long-term survival and a high incidence of bronchiolitis obliterans syndrome (BOS), an inflammation of the small airways in chronic rejection of a lung allograft. There is great clinical need for a minimally invasive biomarker of BOS. Here, 644 different proteins were analyzed to detect biomarkers that distinguish BOS grade 0 from grades 1-3. The plasma
Ex vivo culture of primary acute myeloid leukemia (AML) cells is notoriously difficult due to spontaneous differentiation and cell death, which hinders mechanistic and translational studies. To overcome this bottleneck, we have implemented a co-culture system, where the OP9-M2 stromal cells support the growth, but most notably limit the differentiation of primary AML cells, thus allowing for mecha
Background: Paediatric surgical care is increasingly being centralized away from low-volume centres, and prehospital delay is considered a risk factor for more complicated appendicitis. The aim of this study was to determine the incidence of paediatric appendicitis in Sweden, and to assess whether distance to the hospital was a risk factor for complicated disease. Methods: A nationwide cohort stud
During the 20th century, a number of actors and institutions set out to develop taxonomies of the Swedish population. This thesis examines the most important social classification system, the social group, which despite its great importance in administrative, scientific, commercial, political and media contexts has received little attention in historical research. Invented by the Central Bureau
Reception – hospitality and hostilityMarcus Knutagård and Arne KristiansenSchool of Social Work, Lund UniversityThe aim of this paper is to analyse the practice of reception of newly arrived migrants. The paper is part of an ongoing project Scanian homes: Reception, settlement or rejection – homelessness policies and strategies for refugee settlement. The aim of the project is to investigate the p
Det er kjent fra før at langdistansebinding av refleksive pronomen forekommer i norsk. Fenomenet har blitt kobla til logoforisitet, men det har også blitt hevda at langdistansebinding er mulig i visse ikke-logoforiske kontekster. I denne artikkelen argumenterer jeg for at langdistansebinding i norsk alltid er logoforisk, og at det samme gjelder for mellomdistansebinding. Det er bare lokal binding
Culture-expanded mesenchymal stromal cells (MSCs) are promising candidates for clinical cell-based therapies. MSC products are heterogeneous and we therefore investigated whether acoustophoresis, an ultrasound-based separation technology, could be used for the label-free enrichment of functionally different MSC populations. Acoustophoresis uses an ultrasonic standing wave in a microchannel which d
Reconciliation research consists of two practices, one focusing on the emotional and healing aspects of the process and another that focus on the political and legal actions. Yeudith Auerbach created a theory, the reconciliation pyramid, which aims to manage both aspects. The purpose of this thesis is to apply Auerbach's theory to the reconciliation process in two empirical cases, the Rwandan
The focus of this thesis is an idea named “brukarforum”, a form of collective user participation in residential care. The main purpose of the study is to gain deeper knowledge about “brukarforum” as an idea and its process of institutionalization, i.e. to study whether, and if so in what way, the idea “brukarforum” has become a regular activity in the local practice within the Swedish National
In vivo proton magnetic resonance spectroscopy (1H-MRS) data often exhibit baselines or low-amplitude signal variations resulting from residual water, imperfectly suppressed lipids, low-amplitude metabolites not considered for fitting, and other features not represented in a basis set. While multitudinous approaches exist to model these baselines in 1H-MR spectral analysis, many continue to lack s
INTRODUCTION: Long-term survival following lung transplantation (LTx) faces impediments due to chronic lung allograft dysfunction (CLAD), while infections hinder short-term survival. Fungal colonization and invasive fungal infections (IFI) are common within the first year after LTx. There is ongoing debate regarding the impact of such events on CLAD development and mortality. This study aims to in
Objective: Humanrhinovirus is the most common cause of the common cold worldwide (1). It hasbeen shown that a substantial part of the airborne viruses is found in aerosolparticles in the range of 1-4 µm (2). Studying the infectivity of aerosolparticles in this range is, however, challenging; therefore, not many studieshave been conducted on their infectivity. The aim of this work is toinvestigate
BACKGROUND: In Sweden, managers, individuals working within education, and parents with small children are three groups at high risk for sick leave due to stress-related mental health problems. However, the combined risk of being a parent and manager working within education, i.e., as a principal, on individual work and life satisfaction is not well understood or well-described in the scientific l
Lost Farm Festival transformed an abandoned farm into a global gathering point for grief, anger and creativity – where concerts, rituals and installations turned Sjællands Odde into a new center of the world.
