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During red blood cell (RBC) lysis hemoglobin and heme leak out of the cells and cause damage to the endothelium and nearby tissue. Protective mechanisms exist; however, these systems are not sufficient in diseases with increased extravascular hemolysis e.g. hemolytic anemia. α1-microglobulin (A1M) is a ubiquitous reductase and radical- and heme-binding protein with antioxidation properties. Althou
The paper aims at examining the levels of social cohesion and socio-economic dysfunctionality in former State Agricultural Farms (post-PGR) areas and at assessing the possibilities for initiating bottom-up actions, and for participating in the creation of mechanisms for local development. Data used in the study was obtained in multimethods approach, i.e. mainly during a questionnaire survey, in-de
Det svenska universitetssystemet har vuxit till att bli en omfattande och komplex institution. Expansionen har inte bara gällt antalet studenter, lärare och forskare utan också den administrativa ram de verkar inom och de personalkategorier som ingår däri. Men förhållandet mellan lärarkår och administratörer präglas inte sällan av misstro. I sin artikel vill Ola Agevall och Gunnar Olofsson tränga
Culture-expanded mesenchymal stromal cells (MSCs) are promising candidates for clinical cell-based therapies. MSC products are heterogeneous and we therefore investigated whether acoustophoresis, an ultrasound-based separation technology, could be used for the label-free enrichment of functionally different MSC populations. Acoustophoresis uses an ultrasonic standing wave in a microchannel which d
The UN Convention on the Rights of the Child is a human rights legal document decided and adopted by the UN General Assembly in November 1989. This international convention has had a major impact on children’s rights, policies and legislation in many countries around the world. Another prominent feature of the development, however, is the lack of research in many areas on implementation of childre
Samhällsplaneringen har i någon månalltid varit intresserad av relationellaflöden. Det bilsamhälle som cementeradesunder efterkrigstidens rekordår var ihögsta grad en fråga om att styra rörelsermellan olika platser med industrins behovav arbetskraft som ledstjärna. Men, omvi ser närmare var det inte bara regionplanenstrafiksystem som var relationellt.Bostadsgården skulle skapa platser förolika anv
Hematocrit (HCT) measurements of blood from patients, blood donors and athletes are routinely performed on a daily basis. These measurements are often performed in centralized hospital labs by whole blood analyzers, which leads to long time-to-result. On site measurements, based on centrifugation can be done, but these assays require manual handling, are slow and can just measure HCT in contrast t
Genomic allergen rapid detection (GARD) is an in vitro assay for the prediction of skin sensitizing capacity of chemicals. The GARD assay monitors changes in the expression of 196 genes, termed the GARD prediction signature. In short, MUTZ-3 cells, representing a well-characterized in vitro model of human dendritic cells (DCs), are exposed to the test substances for 24 h. After RNA extraction and
Urbana, pluviala översvämningar orsakar stor skada på infrastruktur, byggnader och stadslivet under och efter extremregn. I den här studien har anmälningar och rapporter från försäkringsbolag och VA-huvudmannen i Malmö, VA Syd, analyserats spatialt. Målsättningen var att få en bättre förståelse för de mekanismer som påverkar pluviala översvämningar, dvs. översvämningar från intensiva regn, ibland Urban, pluvial flooding severely effects infrastructure, buildings and urban life during and after extreme rainfall. In this study, spatial analyses of flood claims from insurance companies and the water utility company of Malmö, VA Syd, are used to better understand the mechanisms and characteristics of pluvial flooding. The same data sets are used to analyse how blue-green infrastructure impacts
