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Wheat bran arabinoxylan can be converted by enzymatic hydrolysis into short arabinoxylo-oligosaccharides (AXOS) with prebiotic potential. Alkali extraction of arabinoxylan from wheat-bran offers advantages in terms of yield and results in arabinoxylan with highly-substituted regions which has been a challenge to hydrolyse using endoxylanases. We show that this hurdle can be overcome by selecting a
On the standard view, an agnostic might commit non-doxastically to religion because she wants to receive some goods, which might be either natural or supernatural in kind. I broaden the picture by showing how the agnostic must also take negative factors into account. Negative mundane factors should be avoided as far as possible by the agnostic, and in extreme cases, even at the price of giving up
In order to produce a more efficient design of a compact turbine driving a cryogenic engine turbo-pump for a satellite delivering rocket, a new supersonic loss model is proposed. The new model was constructed based on high-quality published data, composed of Schlieren photographs and experimental measurements, that combined provided a unique insight into the mechanisms driving supersonic losses. U
Deoxyribonucleoside kinases are feedback inhibited by the final products of the salvage pathway, the deoxyribonucleoside triphosphates. In the present study, the mechanism of feedback inhibition is presented based on the crystal structure of a complex between the fruit fly deoxyribonucleoside kinase and its feedback inhibitor deoxythymidine triphosphate. The inhibitor was found to be bound as a bi
Compact city planning and development has, over the last 30 years or so, been the hegemonic response to the challenges of sustainable development. Global and local policies promote the compact city model due to the positive outcomes of its design principles and strategics as to achieving sustainable cities in terms of their environmental, economic, and social goals. The aim of this paper is to exa
Background: It has been estimated that automated peritoneal dialysis (APD) is currently the fastest growing renal replacement therapy in the world. However, in light of the growing number of diabetic patients on peritoneal dialysis (PD), the unwanted glucose absorption during APD remains problematic. Recent results, using an extended 3-pore model of APD, indicated that large reductions in glucose
Most previous studies about fertility knowledge and attitudes among men have been based on quantitative methods using questionnaires with fixed-choice response options. The aims of this qualitative study were to explore childless young men’s reflections on fertility and infertility through semi-structured interviews. Danish (n = 17) and Swedish (n = 12) young childless men aged between 20 and 30 y
Study Design: Prospective register cohort study. Objectives: The indication for surgery in patients with lumbar spinal stenosis (LSS) is considered to be leg pain and neurogenic claudication (NC). Nevertheless, a significant part of patients operated for LSS have mild leg pain levels defined as leg pain ≤minimally important clinical difference (MICD). Information is lacking on how to inform these
Background Acute bacterial meningitis is a disease with a high mortality and a high incidence of neurological sequelae in survivors. There is an acute need to develop new adjuvant therapies. To ensure that new therapies evaluated in animal models are translatable to humans, studies must evaluate clinically relevant and patient-important outcomes, including neurological symptoms and sequelae. Meth
The activity-size distribution of radiocolloids has been studied using gel-chromatography scanning (GCS) of columns filled with Sepharose 4B gel. Rabbits were injected subcutaneously with the colloid of interest, laid supine beneath a gamma camera, and imaged every 15 sec for 2 to 4 hr. From the stored data, the uptakes in the parasternal lymph nodes were analyzed in terms of a two-compartment mod
In the attempt to reduce greenhouse gas emissions from steel production, several large industry decarbonization projects have emerged in Europe. The commercialization of low-emission steel technology, however, faces systemic barriers such as a lack of infrastructure and unclear demand for greener steel. As part of its new commitment to climate-neutrality, the European Commission has announced plan
The Iranian Light Source Facility is a fourth-generation low emittance synchrotron light source under development in Iran. The design and in-house fabrication of RF cavities are key elements of this project. The choice of 100 MHz capacity loaded RF cavities offers many advantages compared to other cavity types due to a simpler geometry, ease of fabrication, and lower costs for manufacturing and RF
Researches on the modeling of machining difficult-to-cut metals are important for optimization of the processing parameters, in which the force modeling is essential due to its significant influence on the performance of tools and the quality of parts. A semi-analytical method for force prediction in orthogonal cutting with chamfered tools considering both edge and size effect is proposed in this
Staphylococcal toxic shock syndrome is a potentially lethal illness attributed to superantigens produced by Staphylococcus aureus, in particular toxic shock syndrome toxin 1 (TSST-1), but staphylococcal enterotoxins (SEs) are also implicated. The genes encoding these important toxins are carried on mobile genetic elements, and the regulatory networks controlling expression of these toxins remain r
Fatigue safety verification of existing bridges that uses ''re-calculation'' based on codes, usually results in insufficient fatigue safety, triggering invasive interventions. Instead of “re-calculation”, Structural Health Monitoring (SHM) should be used for the assessment of the existing bridges. Monitoring systems provide data that can reduce uncertainties associated with the fatigue loading pro
A software prototype is developed for assessing and updating the reliability of single-cell prestressed concrete box girders subjected to chloride-induced reinforcement corrosion. The underlying system model consists of two integrated sub-models: a condition model for predicting the deterioration state of the box girder and a structural model for evaluating the overall system reliability. The cond
This article explored the use of social media and mobile communication by women in Saudi Arabia who campaigned for the right to drive from 1990. Due to the globally unique ban on women driving in the Kingdom, females always needed a male driver to transport them. The Saudi government announced in September 2017 that women would be allowed to drive from June 2018. Using the theory of connective act
Objective: To develop a preoperative risk model, using endometrial biopsy results and clinical and ultrasound variables, to predict the individual risk of lymph-node metastases in women with endometrial cancer. Methods: A mixed-effects logistic regression model for prediction of lymph-node metastases was developed in 1501 prospectively included women with endometrial cancer undergoing transvaginal
