Filtyp
Young adults presenting with knee pain, instability, or both after twisting the knee during sports or at work are commonly seen in primary care. If the symptoms and injury history correspond with suspicion of a torn anterior cruciate ligament (ACL) or meniscal injury, sometimes in combination with positive findings on magnetic resonance imaging, patients are often referred for surgical treatment.
The large-scale applications of anion exchange membrane water electrolysis (AEMWEs) and zinc–air batteries (ZABs) are observably limited by the lack of highly active, multifunctional, and industrially applicable electrocatalysts. In this work, we report a solvent-free rapid pyrolysis strategy that successfully prepares a composite material of Pt8V–V2O3 heterostructure supported on nitrogen-doped p
Hållbarhetskommunikation tar sig an några av samhällets mest angelägna och komplexa utmaningar. Denna avhandling fördjupar området genom att lyfta fram komplexitet som ett definierande kännetecken för strategisk hållbarhetskommunikation, ett perspektiv som i stort sett har försummats. Den utmanar den dominerande organisationscentriska ansatsen som betraktar kommunikation som ett medel för att uppnSustainability communication confronts some of society’s most pressing and complex challenges. This thesis advances the field by highlighting complexity as a defining characteristic of strategic sustainability communication, a perspective that has been largely neglected. It challenges the dominant organization-centric approach that frames communication as an instrument for achieving corporate goal
Scientific breakthroughs in the field of cell and gene therapy lay the groundwork for therapeutic innovation, but their translation and integration into routine care is delayed by systemic inefficiencies and limited cross-sector alignment. The Advanced Therapies model of Lund is a proactive and integrated approach designed to accelerate the development of advanced therapies from discovery to reimb
Background: Virtual imaging trials (VITs) are in silico studies that simulate medical imaging and disease processes, offering a cost-effective and reproducible addition to traditional imaging trials. While VITs are well established in breast imaging, most existing implementations simulate imaging based on static anatomical models, capturing only a single time point. This limits their ability to st
Oily wastewater presents a serious environmental challenge, demanding sustainable and regenerative membrane technologies. Here, we report a green and scalable method for fabricating skin-replaceable cellulose membranes (SRC-M) from jute agro-waste, using a NaOH/urea activation route and argon-pressurized deposition onto ceramic supports. The resulting Cellulose II-based asymmetric membranes exhibi
Introduction: Implementing new treatment regimens entails a learning phase with a concomitant risk of suboptimal results. High caseload has generally been shown to improve results in complex surgical procedures. This study aimed to evaluate results of Cytoreductive Surgery (CRS) and Intraperitoneal Chemotherapy (IP), given as Early Postoperative Intraperitoneal Chemotherapy (EPIC) or Hyperthermic
This study evaluated the adaptation of relapse prevention treatment, originally for substance use, to address problematic gaming in children and adolescents. The goal was to understand the feasibility of this treatment in child and adolescent mental health services from the clinicians’ perspective. Six clinicians, four women and two men aged 37–47 with 4–20 years of work experience, were interview
Background: Following the results of the MANDARA trial, this real-life study aimed at comparing the effectiveness and safety profile of mepolizumab versus benralizumab in a European EGPA cohort. Methods: We conducted a retrospective observational comparative study including EGPA patients, who received mepolizumab or benralizumab at the asthma dose. Patients were matched 1:1 by sex, age, BVAS and o
Introduction: Oesophageal resection carries significant morbidity and mortality. Artificial intelligence (AI) advances in medical research enable enhanced predictions, flexibility, and interpretability, especially for complex interactions and nonlinear relationships. Material and methods: We used a register-based case-control design nested within prospectively collected data from the Swedish Natio
AIMS: Biomarkers associated with asymptomatic ventricular dysfunction might improve risk stratification and identify pathways leading to heart failure (HF). We explored the association between proteomic biomarkers and left ventricular hypertrophy (LVH), diastolic dysfunction (DD) and incident HF in three population-based cohorts.METHODS AND RESULTS: A chip was used to measure 92 protein biomarkers
Using a case-controlled study including siblings of major depression (MD) and control probands, born 1970–1990 and followed through 2018, we sought to clarify the degree to which the familial liability to MD is reflected in its clinical features, and the pattern of psychiatric disorders at elevated risk in the siblings of MD probands. The study population included full-siblings of 197,309 MD and m
The Arctic is undergoing a shift toward a warmer and wetter climate. Recent experiments indicate that the carbon balance of subarctic wet tundra is sensitive to both summer warming and deeper snow. However, few studies have combined experimental data with process-oriented models to predict how the terrestrial carbon cycle will respond to future climate change. Here, we use CoupModel, a process-ori
This article argues that the construction ἔχειν πίστιν in Hellenistic Greek is a nominalized ideational metaphor that is semantically related to the finite verb πιστεύειν. Therefore, when the construction possesses a genitive modifier, the function of the genitive is disambiguated as denoting the object of πίστιν. This understanding of ἔχειν πίστιν + the genitive has significant implications for i
The Concordance Index (C-index) is a commonly used metric in Survival Analysis for evaluating the performance of a prediction model. In this paper, we propose a decomposition of the C-index into a weighted harmonic mean of two quantities: one for ranking observed events versus other observed events, and the other for ranking observed events versus censored cases. This decomposition enables a finer
The clinical translation of induced pluripotent stem cells (iPSCs) holds great potential for personalized therapeutics. However, one of the main obstacles is that the current workflow to generate iPSCs is expensive, time-consuming, and requires standardization. A simplified and cost-effective microfluidic approach is presented for reprogramming fibroblasts into iPSCs and their subsequent different
