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Minimal Contribution of Fasting Hyperglycemia to the Incidence of Type 2 Diabetes in Subjects With Normal 2-h Plasma Glucose

OBJECTIVE - To assess the relative contribution of increased fasting and postload plasma glucose concentrations to the incidence of type 2 diabetes in subjects with a normal 2-h plasma glucose concentration. RESEARCH DESIGN AND METHODS - A total of 3,450 subjects with 2-h plasma glucose concentration < 140 mg/dl at baseline were followed up in the San Antonio Heart Study (SAHS) and the Botnia Stud

Effects of Genetic Variants Previously Associated with Fasting Glucose and Insulin in the Diabetes Prevention Program

Common genetic variants have been recently associated with fasting glucose and insulin levels in white populations. Whether these associations replicate in pre-diabetes is not known. We extended these findings to the Diabetes Prevention Program, a clinical trial in which participants at high risk for diabetes were randomized to placebo, lifestyle modification or metformin for diabetes prevention.

Cerebral inflammation is an underlying mechanism of early death in Alzheimer's disease: a 13-year cause-specific multivariate mortality study.

Introduction: Although Alzheimer’s disease (AD) is associated with early death, its life expectancy differs greatly between patients. A better understanding of this heterogeneity may reveal important disease mechanisms underlying the malignancy of AD. The aim of this study was to examine the relation between AD pathologies and early death in AD caused by dementia. Methods: At a memory clinic, 247

Förekommer det ett samband mellan styrelseledamöters parallella styrelseuppdrag och företags tillväxt? / Is there a connection between board of director’s parallel board assignments and company’s growth?

Syftet med vår uppsats är att undersöka om det finns ett samband mellan medelstora aktiebolags tillväxt och styrelseledamöters antal parallella styrelseuppdrag och hur detta samband i sådant fall ser ut. // To investigate if there is a connection between the board of director’s number of parallel board assignments and the growth of midsized corporations. And if that’s the case then see how this co

Quantitative tissue classication with dual-energy computed tomography for radiation treatment planning evaluation and optimization of a new method

A new method to extract mass density and elemental compositions of tissues from dual-energy computed tomography (DECT) scans is described and investigated. The method decomposes a tissue into proportions of two or three predened base materials and was proposed in 2008 by a research team at Linkoping University. Informations of tissue parameters may be important in radiation treatment planning to c

The Proposed Regulation on a Common European Sales Law (CESL) as an Alternative to the Convention on the International Sale of Goods (CISG) in Transnational Business-to-Business Transactions?

The Commission has put forth a proposal for a Regulation on a Common European Law of Sales (CESL). It is envisaged – as of now – as an optional second regime within each member state‘s law, electable for transnational consumer contracts and contracts among traders, as long as one of them is a small or medium-sized enterprise. The intention is to provide contractors with a level playground of one l

Reverse Payment Patent Settlements as Restrictions by Object under Article 101(1) TFEU

Förevarande uppsats undersöker EU-domstolens praxis avseende värdeöverföringar mellan originaltillverkare av läkemedel och generikaföretag i samband med patentförlikningar (så kallade ‘RPPSs’) för att urskilja under vilka förutsättningar ett sådant förfarande utgör en syftesöverträdelse. Analysen visar att EU-domstolens avgöranden Generics och Lundbeck förtydligar bedömningen av mer okompliceradeThis thesis examines the CJEU’s case law on value transfers between originator and generic undertakings, in the context of patent settlements, to ascertain the criteria for determining when such a practice amounts to a restriction of competition by object. The thesis finds that the CJ’s rulings in Generics and Lundbeck clarifies the treatment of more straightforward RPPSs and follows established

Integritet: En kvalitativ undersökning kring hur onlinetjänster bättre kan tillgodose den digitala konsumentens önskemål kring datainsamling

Det råder en global kontinuerlig teknikutveckling som präglar internet med nya innovationer. Många onlinetjänster på internet bedriver sina verksamheter med hjälp av datainsamling av de digitala konsumenterna. Teknikutveckling kräver en insats från både onlinetjänster som behöver vara fortsatt anpassningsbara och digitala konsumenter som behöver begripa vilka konsekvenser utveckling har. Datainsam

Det tredelade föräldraskapet - begreppet utan definition. En kvantitativ studie om yrkesverksammas kunskapsläge, arbetssätt och attityd till det tredelade föräldraskapet

Three-part parenting is an approach that social services in Sweden should use in collaboration around a child placed in foster care. It describes how foster home, parents and social services share responsibilities for the welfare of the child. The purpose of this study was to illuminate the state of knowledge about the approach among social workers working with children and adolescents in Sweden.

The Interactions and Role-changings between the LGBTQIA+ Community and the Creative Industries in Guangzhou, China Focusing on Women’s Opinion in the LGBTQIA+ Community

This thesis examines the interactions and role-changings between the LGBTQIA+ community and the creative industries in Guangzhou, China. Following Florida’s (2003) creative capital theory, and Badgett, Waaldijk, and Rodgers’s (2019) study on LGBT inclusion and economic development, involving semi-structured interviews with LGBTQIA+ individuals working or studying in the creative industries. This q

"Vi kan ju bara motivera" - En studie om självbestämmande på LSS-boende

The aim of this study is to investigate how staff who work with persons with mental impairment living in supportive housing describe and reflect on the clients´ self-determination and which options and challenges they experience with respect to putting the intent of the Swedish act concerning support and service for people with certain functional impairments (LSS) regarding self-determination into

Adolescent Mental Health: Impact of Introducing Earlier Compulsory School Grades

The prevalence of mental ill-health is increasing among young people in many developed countries, raising concerns about their well-being. Experts have pointed to several potential contributing factors, including a heightened emphasis on educational achievement and performance evaluation, as well as shifting demands in the high-skilled job market. In this paper, we study the effect of introducing