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Stapylococcus aureus is a common infectious agent in e.g. sepsis, associated with both high mortality rates and severe long-term effects. The cytolytic protein α-hemolysin has repeatedly been shown to enhance the virulence of S. aureus. Combined with an unhindered spread of multi drug-resistant strains, this has triggered research into novel anti virulence (i.e. anti α-hemolysin) drugs. Their func

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After the disintegration of the Soviet Union, the national identities of the Eastern and Central European states are finding themselves in a process of transformation and the results are having an impact on international relations in the region. National and foreign political identities of states are constituted by means of everyday discursive practices, not least in the media. In the present stud

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A novel optical design for a flexible SAXS beamline at a modern synchrotron has been implemented for the CoSAXS beamline at the 3GeV ring at the MAX TV Laboratory. The performance of the beamline has been simulated through combined ray tracing and wave propagation with the code xrt taking into account the low emittance and highly coherent beam of MAX TV and the short inter-optics distances of the

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Satellite remote sensing, with its unique synoptic coverage capabilities, can provide accurate and immediately valuable information on fire analysis and post-fire assessment, including estimation of burnt areas. In this study the potential for burnt area mapping of the combined use of Artificial Neural Network (ANN) and Spectral Angle Mapper (SAM) classifiers with Landsat TM satellite imagery was

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Objectives To use the estimates from the Global Burden of Disease Study 2016 to describe patterns of suicide mortality globally, regionally, and for 195 countries and territories by age, sex, and Socio-demographic index, and to describe temporal trends between 1990 and 2016. Design Systematic analysis. Main outcome measures Crude and age standardised rates from suicide mortality and years of life

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Ecosystem services inherently involve people, whose values help define the benefits of nature's services. It is thus important for researchers to involve stakeholders in ecosystem services research. However, a simple and practicable framework to guide such engagement, and in particular to help researchers anticipate and consider key issues and challenges, has not been well explored. Here, we use e

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Surface waters can contain a diverse range of organic pollutants, including pesticides, pharmaceuticals and industrial compounds. While bioassays have been used for water quality monitoring, there is limited knowledge regarding the effects of individual micropollutants and their relationship to the overall mixture effect in water samples. In this study, a battery of in vitro bioassays based on hum

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We present 77 new granite whole-rock analyses from the Qattar and Gharib areas, Eastern Desert, Egypt. Both areas include a “normal” granite and either a hypersolvus (Gharib) or an almost plagioclase-free granite (Qattar) enriched in fluorite. According to earlier results, F influences element distribution in granitic melts forming complexe

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Human use of natural resources poses a great challenge to social-ecological and socio-technical sys- tems alike: supply risks, pollutant and greenhouse gas emissions, waste generation on the one hand, but also issues of global justice and societal well-being on the other hand. In order to test potential im- pacts of developments and strategies relevant to resource policy, the SimRess project first

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Palaeomagnetic analyses were conducted on two varved lake-sediment sequences in northern Sweden. The magnetic properties of the sediment sequences are dominated by stable single-domain magnetite with characteristics typical of bacterial magnetosomes. Alternating field demagnetization measurements indicate that the single-domain magnetite is the dominant carrier of a stable natural remanent magneti

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Mine waste rock piles (WRPs) can contain sulfidic minerals whose interaction with oxygen and water can generate acid mine drainage (AMD). Thus, WRPs can be a long-term source of environmental pollution. Since the generation of AMD and its release into the environment is dependent on the net volume and bulk composition of waste rock, effective characterization of WRPs is necessary for successful re

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OBJECTIVES: To investigate differences in ulcer healing time and waiting time between video consultation and inperson assessment for patients with hard-to-heal ulcers.SETTING: Patients treated at Blekinge Wound Healing Centre, a primary care centre covering the whole of Blekinge county (150 000 inhabitants), were compared with patients registered and treated according to the Registry of Ulcer Trea

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The old city of Fez, Morocco, classified as Heritage of Humankind by the UNESCO, is subject to an integrated rehabilitation plan running over 15 years. The plan aims at restoring and preserving the economy, cultural value, and social heritage of the old city. The study follows a system dynamics approach to describe and analyze the rehabilitation plan in order to identify the strengths and defects

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Men with spine fractures have reduced vertebral body (VB) volume and volumetric bone mineral density (vBMD). Men with hip fractures have reduced femoral neck (FN) volume and vBMD, site-specific deficits that may have their origins in growth. To describe the tempo of growth in regional bone size, bone mineral content (BMC), and vBMD, we measured bone length, periosteal and endocortical diameters, B

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Supernormal clutches are found across bird species. Such clutches often result from more than one female laying eggs in the same nest and can reflect different behaviours from parasitism to laying mistakes. Enlarged clutches are readily visible among waders due to a maximum maternal clutch size of four eggs, yet surprisingly little is known about this phenomenon. Since supernormal clutches are rar

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WORLD6 model was developed and applied to simulate potential future supply and scarcity of a num- ber of natural resources within the system dynamics modelling workpackage of the SimRess project. The main objective of this report is to outline the overall structure of the WORLD6 model and provide a detailed description of the “resources” module implemented in the model.In the WORLD6 model, resourc

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A new PCR kit (AMPLICOR CT/NG; Roche Diagnostic Systems, Inc., Branchburg, N.J.) was used as a screening tool for the detection of Chlamydia trachomatis and Neisseria gonorrhoeae in first-void urine (FVU) specimens from 3,340 asymptomatic women attending European health care units for contraceptive advice or pregnancy termination. All samples were kept frozen (-20 degrees C) prior to testing. Chla

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Mass production and consumption based on virgin materials have been the mainstream practice for decades across industrialised nations. Resource consumption has reached an unsustainable level, leading to devastating environmental impacts. For a more sustainable future, not only environmentally but economically and socially, material cycles need to be slowed down and, if possible, closed. Upcycling

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Global urbanisation, increasing population, economic growth and development have caused increase in resource consumption, and consequently, a vast volume of waste and other negative environmental impacts. In order to reduce negative environmental impact, various approaches to resource management have been suggested and implemented in the system of production, consumption and waste management. One