Filtyp
Background: Lipoprotein(a) concentrations in plasma are associated with cardiovascular risk in the general population. Whether lipoprotein(a) concentrations or LPA genetic variants predict long-term mortality in patients with established coronary heart disease remains less clear. Methods: We obtained data from 3313 patients with established coronary heart disease in the Ludwigshafen Risk and Cardi
Site-specific land management practice taking into account variability in maize yield gaps (the difference between yields in the 90th percentiles and other yields on smallholder farmers’ fields) could improve resource use efficiency and enhance yields. However, the applicability of the practice is constrained by inability to identify patterns of resource utilization to target application of resour
With the adoption of the Sustainable Development Goals (SDGs), debates on governance through goal-setting and performance review have gained momentum. In this article, we explore how the politics of performance review played out in public sustainable development reporting at the global-national nexus. By examining the case of Swedish reporting to the United Nations High Level Political Forum in 20With the adoption of the Sustainable Development Goals (SDGs), debates on governance through goal-setting and performance review have gained momentum. In this article, we explore how the politics of performance review played out in public sustainable development reporting at the global-national nexus. By examining the case of Swedish reporting to the United Nations High Level Political Forum in 20
Importance: Prognostication of neurologic outcome after cardiac arrest is an important but challenging aspect of patient therapy management in critical care units. Objective: To determine whether serum neurofilament light chain (NFL) levels can be used for prognostication of neurologic outcome after cardiac arrest. Design, Setting and Participants: Prospective clinical biobank study of data from t
Plasma biomarkers that reflect molecular states of the cardiovascular system are central for clinical decision making. Routinely used plasma biomarkers include troponins, natriuretic peptides, and lipoprotein particles, yet interrogate only a modest subset of pathways relevant to cardiovascular disease. Systematic profiling of a larger portion of circulating plasma proteins (the plasma proteome) w
Uncertainty refers to any limitation in knowledge. Identifying and characterizing uncertainty in conclusions is important to ensure transparency and avoid over or under confidence in scientific assessments. Quantitative expressions of uncertainty are less ambiguous compared to uncertainty expressed qualitatively, or not at all. Subjective probability is an example of a quantitative expression of e
Dysfunctional water, sanitation and hygiene (WaSH) systems are mainly determined by poor water governance, exacerbating inequalities and poverty. Multi-stakeholder partnerships provide an approach to more flexible and adaptive governance to explore these problems. In this article, national commitments made to improve WaSH, made through the Sanitation and Water for All (SWA) partnership’s Mutual Ac
The ongoing wide-scale introduction of nonnative plants across the world may negatively influence native invertebrate fauna, due to a lack of coevolved traits related to the novel plants, e.g., unique phytochemicals or shifted phenology. Nonnative plants, specifically trees, are common in urban environments, areas that already pose novel habitats to plants and wildlife through a wide array of anth
Increasing exports of Fe and DOC from soils, causing browning of freshwaters, have been reported in recent decades in many regions of the northern hemisphere. Afforestation, and in particular an increase of Norway spruce forest in certain regions, is suggested as a driver behind these trends in water chemistry. In this study, we tested the hypothesis that the gradual accumulation of organic soil l
The immersion freezing ability of soot particles has in previous studies been reported in the range of low/insignificant to very high. The aims of this study were to: (i) perform detailed physico-chemical characterisation of freshly produced soot particles with very different properties, (ii) investigate the immersion freezing ability of the same particles, and (iii) investigate the potential link
Riverine colloids are important carriers of macronutrients, trace metals, and pollutants into marine waters. The aim of the current study was to extend the understanding of iron (Fe) and organic carbon (OC) colloids in boreal rivers and their fate at higher salinities. X-ray absorbance spectroscopy (XAS) and dynamic light scattering (DLS) were combined to explore Fe speciation and colloidal charac
Importance To our knowledge, there is no consensus regarding when individuals who repeatedly self-harm and are at risk of suicide should be hospitalized. To evaluate a new alternative, we examined the effects of brief admission (BA) to hospital by self-referral.Objectives To determine the effects of BA on inpatient service use and on secondary outcomes of daily life functioning, nonsuicidal self-
Duplicative horizontal gene transfer may bring two previously separated homologous genes together, which may raise questions about the interplay between the gene products. One such gene pair is the “native” PgiC1 and “foreign” PgiC2 in the perennial grass Festuca ovina. Both PgiC1 and PgiC2 encode cytosolic phosphoglucose isomerase, a dimeric enzyme whose proper binding is functionally essential.
How do fungi navigate through the complex microscopic maze-like structures found in the soil? Fungal behaviour, especially at the hyphal scale, is largely unknown and challenging to study in natural habitats such as the opaque soil matrix. We monitored hyphal growth behaviour and strategies of seven Basidiomycete litter decomposing species in a micro-fabricated "Soil Chip" system that simulates pr
Background: It has been shown previously that an anterior cruciate ligament injury may affect postural control, measured by balance in single-limb stance. To our knowledge, no studies have reported the influence of measures of impairment on postural control after such an injury. Purpose: To assess the influence of knee laxity, proprioception, and muscle strength on balance in single-limb stance an
RATIONALE: Very preterm infants (i.e. born before 32 weeks of gestation) are at risk of cerebral injury and long-term neurodevelopmental impairment. Cerebral near-infrared spectroscopy (NIRS) enables continuous monitoring of cerebral oxygenation to guide clinical management. Interest in NIRS has grown in recent years, highlighting the need for better evidence to support its clinical efficacy in im
INTRODUCTION: Sexual life is important for many people and may be limited by breathlessness. We evaluated associations between breathlessness and individuals' perceived satisfaction with sexual lives and explored mediating factors in this relationship. METHODS: A cross-sectional, online, population-based survey of Australian adults with key demographics (age, sex, rurality, state/territory) reflec
In the pursuit of more sustainable agriculture, weeds play a dual role by threatening crop production and simultaneously contributing to farmland biodiversity. Management actions such as the use of fertilisers (fertilisation) may change weed abundance and community composition with consequences for both weed–crop competition and biodiversity. Alleviating the balance between yield and biodiversity
DevOps has significantly improved the software development life-cycle by enabling fast, automated, and continuous integration and deployment (CI/CD). However, its application to Cyber-Physical Systems (CPS) presents unique challenges that require rethinking of traditional practices. DevOps in CPS becomes even more challenging when we consider sustainability, which is becoming increasingly importan
