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Aim: To determine the ability of serum glial fibrillary acidic protein (GFAp) and tau protein to predict neurological outcome after out-of-hospital cardiac arrest (OHCA). Methods: We measured plasma concentrations of GFAp and tau of patients included in the previously published COMACARE trial (NCT02698917) on intensive care unit admission and at 24, 48, and 72 h after OHCA, and compared them to ne

Background: Adolescent anxiety and depression are highly prevalent psychiatric disorders that are associated with altered molecular and neurocircuit profiles. Recently, increased mitochondrial DNA copy number (mtDNA-cn) has been found to be associated with several psychopathologies in adults, especially anxiety and depression. The associations between mtDNA-cn and anxiety and depression have not,

The X-ray scanning microscope PtyNAMi at beamline P06 of PETRA III at DESY in Hamburg, Germany, is designed for high-spatial-resolution 3D imaging with high sensitivity. Besides optimizing the coherent ux density on the sample and the precision mechanics of the scanner, special care has been taken to reduce background signals on the detector. The optical path behind the sample is evacuated up unti

Variations in the POLG1 gene encoding the catalytic subunit of the mitochondrial DNA polymerase gamma, have recently been associated with Parkinson's disease (PD), especially in patients diagnosed with progressive external ophthalmoplegia (PEO). However, the majority of the studies reporting this association mainly focused on the genetic identification of the variation in POLG1 in PD patient prima

α-Synuclein is a presynaptic protein associated to Parkinson's disease, which is unstructured when free in the cytoplasm and adopts α helical conformation when bound to vesicles. After decades of intense studies, α-Synuclein physiology is still difficult to clear up due to its interaction with multiple partners and its involvement in a pletora of neuronal functions. Here, we looked at the remarkab

N-terminal pro-B-type natriuretic (NT-proBNP) is expressed in the heart and brain, and serum levels are elevated in acute heart and brain diseases. We aimed to assess the possible association between serum levels and neurological outcome and death in comatose patients resuscitated from out-of-hospital cardiac arrest (OHCA). Of the 939 comatose OHCA patients enrolled and randomized in the Targeted

The European Resuscitation Council (ERC) and the European Society of Intensive Care Medicine (ESICM) have collaborated to produce these post-resuscitation care guidelines for adults, which are based on the 2020 International Consensus on Cardiopulmonary Resuscitation Science with Treatment Recommendations. The topics covered include the post-cardiac arrest syndrome, diagnosis of cause of cardiac a

Background: The kynurenine pathway enzymes, breaking down tryptophan, are abundant in placental tissue. These metabolites are involved in immunoregulatory mechanisms, although the role of this pathway in pre-eclampsia (PE) has only begun to be characterized. Here, we determined tryptophan and metabolite levels together with the expression of kynurenine pathway enzymes and inflammatory factors in p

Background: Cardiac arrest (CA) represents the third leading cause of death worldwide. Among patients resuscitated and admitted to hospital, death and severe neurological sequelae are frequent but difficult to predict. Blood biomarkers offer clinicians the potential to improve prognostication. Previous studies suggest that circulating non-coding RNAs constitute a reservoir of novel biomarkers. The

Small cell lung cancer (SCLC) is characterized by rapid growth and high metastatic capacity. It has strong epidemiologic and biologic links to tobacco carcinogens. Although the majority of SCLCs exhibit neuroendocrine features, an important subset of tumors lacks these properties. Genomic profiling of SCLC reveals genetic instability, almost universal inactivation of the tumor suppressor genes TP5

Background and aims: Several different scoring systems for early risk stratification after out-of-hospital cardiac arrest have been developed, but few have been validated in large datasets. The aim of the present study was to compare the well-validated Out-of-hospital Cardiac Arrest (OHCA) and Cardiac Arrest Hospital Prognosis (CAHP)-scores to the less complex MIRACLE2- and Target Temperature Mana

Context: Medications may become inappropriate for patients in the last phase of life and may even compromise their quality of life. Objective: To find consensus on recommendations regarding deprescribing of medications for adult patients with a life expectancy of six months or less. Methods: Experts working in palliative care or other relevant disciplines were asked to participate in this internat

Most migratory birds return every year to the same breeding sites and some species show a similarly high fidelity to wintering grounds as well. Fidelity to stopover sites during migration has been much less studied and is usually found to be lower. Here, we investigate site fidelity and distance to previously visited sites throughout the annual cycle in the common cuckoo, a nocturnal trans-Saharan

Background: The CTLA-4 blocking antibody ipilimumab has demonstrated substantial and durable effects in patients with melanoma. While CTLA-4 therapy, both as monotherapy and in combination with PD-1 targeting therapies, has great potential in many indications, the toxicities of the current treatment regimens may limit their use. Thus, there is a medical need for new CTLA-4 targeting therapies wit

We do not yet know how the robotization of eldercare will unfold, but one thing is clear: technology mediates human practices and experiences [1]. As such, care robots will co-shape the actions of care givers and older people and influence the perceptions and experiences of old age. The robotization of eldercare means that it is essential for developers, policy makers, and researchers to become in

Tentamen Datum: 2025-10-01 Kurs: Kunskapsteori (FTEA21:1) Examinerande lärare: Erik J. Olsson Maxpoäng: 10 Poäng för godkänt: 5 Poäng för väl godkänt: 8 Postadress Kungshuset, 222 22 Lund Besöksadress Kungshuset, Lundagård Telefon dir 046-222 75 93, växel 046-222 00 00 Telefax 046-222 44 24 Internet WWW.fil.lu.se E-post fil@fil.lu.se Filosofiska institutionen Tentamen: Obs! Viktig information om l

https://www.ht.lu.se/media/utbildning/dokument/kurser/FTEA21/20261/Exempeltentor_VT26_teoretisk_filosofi_forts_ttningskurs.pdf - 2026-05-21

Microsoft Word - Exjobb_4-7-2020.docx Master’s Dissertation Structural Mechanics Report TV SM -5247 ERIK TU N LID and JO EL VÄ RELÄ EX PER IM EN TA L C H A R A C TER IZA TIO N A N D C O M PU TA TIO N A L D Y N A M IC M O D ELLIN G O F A V IO LIN ERIK TUNLID and JOEL VÄRELÄ EXPERIMENTAL CHARACTERIZATION AND COMPUTATIONAL DYNAMIC MODELLING OF A VIOLIN Analysing the effects of creep and string tensio

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm5000/web5247.pdf - 2026-05-30

Dinka and the architecture of long-distance extraction∗ Coppe van Urk (cvanurk@mit.edu) Norvin Richards (norvin@mit.edu) Massachusetts Institute of Technology GLOW 36, Lund University In the Nilotic language Dinka Nyarweng, both C and v have the EPP property: one XP must sit in their specifier (1) and (2): (1) CP XP C’ C TP . . . (2) vP XP v’ v VP . . . In this talk, we show that this system provi

https://konferens.ht.lu.se/fileadmin/user_upload/sol/ovrigt/konferens_glow36/Handouts_and_Presentations/van_Urk_and_Richards.pdf - 2026-05-30

Aktuellt om v&h med bilder NY.indd 1 A K T U EL LT O M V E T ENSK A P O CH HÄ L SA • N OV 20 05 Den medicinska bilden November 2005 Denna tidskrift ges ut av Medicinska fakulteten vid Lunds universitet och Universitetssjukhuset i Lund & Universitetssjukhuset MAS vid Region Skåne Aktuellt om VETENSKAP & HÄLSA 2 A K T U EL LT O M V E T ENSK A P O CH HÄ L SA • N OV 20 05 Aktuellt om VETENSKAP & HÄLSA

https://www.vetenskaphalsa.se/wp-content/uploads/2010/08/Aktuellt_om_vet_o_halsa_nov_05.pdf - 2026-05-30