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From Medication to Education - People with autism in adult psychiatry

This dissertation concerns the field of applied psychiatry and focuses on the problems that are associated with the care and treatment of adult patients with autism spectrum disorders. The conditions that are described are valid for Swedish psychiatry and cannot be directly generalized to conditions outside of the country.

Interstitial photodynamic therapy for primary prostate cancer incorporating realtime treatment dosimetry

Photodynamic therapy (PDT) for the treatment of prostate cancer has been demonstrated to be a safe treatment option capable of inducing tissue necrosis and decrease in prostate specific antigen (PSA). Research groups report on large variations in treatment response, possibly due to biological variations in tissue composition and shortterm response to the therapeutic irradiation. Within our group,

Some consequences of atmospheric dispersion for ELTs

Previously the effect of atmospheric dispersion on telescope performance has attracted only relatively little attention. This may be due to the fact that the dispersion effects have been evaluated in relation to the size of the diffraction limited resolution angle of current telescopes, or to seeing limited telescopes. However, since the resolution angle is inversely proportional to telescope diam

A new concept for large deformable mirrors for extremely large telescopes

For extremely large telescopes, there is strong need for thin deformable mirrors in the 3-4 m class. So far, feasibility of such mirrors has not been demonstrated. Extrapolation from existing techniques suggests that the mirrors could be highly expensive. We give a progress report on a study of an approach for construction of large deformable mirrors with a moderate cost. We have developed low-cos

It is important that the process goes quickly, isn't it?” A qualitative multi-country study of colorectal or lung cancer patients’ narratives of the timeliness of diagnosis and quality of care

Purpose: The emphasis on early diagnosis to improve cancer survival has been a key factor in the development of cancer pathways across Europe. The aim of this analysis was to explore how the emphasis on early diagnosis and timely treatment is reflected in patient's accounts of care, from the first suspicion of colorectal or lung cancer to their treatment in Denmark, England and Sweden. Method: We

The need for country masks for future national greenhouse gas flux estimations

The Paris Agreement requests a substantial reduction of greenhouse gas (GHG) emissions. These emissions are currently mainly estimated from bottom-up inventories and process-based models of land and ocean fluxes. Another, complementary approach is based on measurements of the atmospheric GHG concentration in combination with atmospheric inverse modelling to provide the GHG fluxes. For the latter a

Sharing building information from planning to maintenance phases

The sharing of digital information between phases in the planning and building process still have shortcomings. Ourstudy is performed as a test case on a construction project in a municipality and focuses on two aspects of how the sharing of building information could be improved: 1) to get a more process oriented approach to the information flow. Here we will test if the ISO-standard Product Life

Dynamic Glucose-Enhanced (DGE) MRI: Translation to Human Scanning and First Results in Glioma Patients.

Recent animal studies have shown that D-glucose is a potential biodegradable MRI contrast agent for imaging glucose uptake in tumors. Here, we show the first translation of that use of D-glucose to human studies. Chemical exchange saturation transfer (CEST) MRI at a single frequency offset optimized for detection of hydroxyl protons in D-glucose (glucoCEST) was used to image dynamic signal changes

Varandra som vänner och fiender - en idékritisk undersökning om kontraktet och dess grund.

Popular Abstract in Swedish Den här boken handlar om ömsesidighet i sociala relationer - om vänskap. Den handlar också om de moraliska och rättsliga normer och föreställningar som istället främjar ensidiga, eller till och med direkt fientliga, relationer. Arbetet utgår från vissa centrala punkter i den aristoteliska etiken. Undersökningen kretsar kring de värden som konstituerar den sociala relatiThis is a book about reciprocity in social relationships - about friendship. It also deals with the moral and legal norms which, conversely, promote one-sided and even directly hostile relationships. The starting-point for this work is certain central elements in Aristotelian ethics. The study revolves around the values which constitute the social relationship of friendship and the central questio

Rural-urban interdependencies : The role of cities in rural growth

A massive population growth in cities is currently being witnessed in most countries around the world. As urban populations grow, cities eventually expand geographically into what was considered countryside and nowadays distinguishing between what is city and what is countryside is getting increasingly difficult. In many Western countries, it is being observed that areas near cities seem to capita

Dysglycemia, glycemic variability, and outcome after cardiac arrest and temperature management at 33°C and 36°C

Objectives: Dysglycemia and glycemic variability are associated with poor outcomes in critically ill patients. Targeted temperature management alters blood glucose homeostasis. We investigated the association between blood glucose concentrations and glycemic variability and the neurologic outcomes of patients randomized to targeted temperature management at 33°C or 36°C after cardiac arrest. Desig

Biological predictors of insulin resistance associated with posttraumatic stress disorder in young military veterans

Posttraumatic stress disorder (PTSD) is associated with increased risk for Type 2 diabetes and cardiovascular disease (cardiometabolic disease), warranting research into targeted prevention strategies. In the present case–control study of 160 young (mean age 32.7 years) male military veterans, we aimed to assess whether PTSD status predicted increased markers of cardiometabolic risk in otherwise h

Implementation of the Trade Secrets Directive into National Law: Portugal and Spain

The protection of trade secrets in Portugal and Spain has been derived from general legal principles (of Civil Law, Penal Law and Unfair Marketing Law). This chapter on implementation of the Trade Secrets Directive (TS Directive) in Portugal and Spain presents the traditional views and positions and the implementation of the TS Directive into the respective national legal orders.In Portugal, imple

Distinct global binding patterns of the Wilms' tumor gene 1 (WT1) -KTS and +KTS isoforms in leukemic cells

The zinc finger transcription factor Wilms' tumor gene 1 (WT1) acts as an oncogene in acute myeloid leukemia. A naturally occurring alternative splice event between zinc fingers three and four, removing or retaining three amino acids (+/-KTS), is believed to change the DNA binding affinity of WT1, although there are conflicting data regarding the binding affinity and motifs of the different isofor