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Children with bone marrow failure syndromes and severe aplastic anemia (SAA) are treated with allogeneic blood or marrow transplantation (BMT). However, there is a paucity of studies examining late mortality risk after allogeneic BMT performed in childhood for bone marrow failure syndromes and SAA and evaluating how this risk differs between these diseases. We investigated cause-specific late mort

This work investigates the stability of emulsions prepared by using octenyl succinic anhydride (OSA)-modified waxy maize starch in the form of granules, dissolved starch, and non-solvent precipitated starch as Pickering emulsion stabilisers. The aim of this study was to investigate the effects of different forms of starches on the stability of emulsion using light microscopy, light scattering, and

Background: There exist few recovery and occupation-based interventions for mental health service users. Balancing Everyday Life (BEL) is a new occupation-based lifestyle intervention that was created to fill this need. Aim: To gain group leaders’ and participants’ perspectives of the BEL intervention content and format, including factors that helped, hindered, and could be improved. Methods: A co

Background: Metronidazole is the preferred empirical anti-anaerobic agent for patients with suspected anaerobic infection. The balance between benefits and harms of empirical metronidazole is unclear. We aimed to assess patient-important benefits and harms of empirical metronidazole vs placebo/no treatment in adult patients with severe bacterial infection of any origin. Methods: We conducted a sys

The sharing economy is a new form of resource distribution that is affecting traditional markets, cities and individuals, and challenging the prevalent regulatory frameworks, social norms and belief systems. While studies have examined some of its disruptive effects on institutional actors, there has been less focus on the ways in which sharing economy organisations work to create new or disrupt p

It has been hypothesized that highly productive coastal ecosystems, such as seagrass meadows, could lead to the establishment of ocean acidification (OA) refugia, or areas of elevated pH and aragonite saturation state (Ωa) compared to source seawater. However, seagrass ecosystems experience extreme variability in carbonate chemistry across short temporal and small spatial scales, which could impac

We have combined three techniques, High Energy Surface X-Ray Diffraction (HESXRD), Surface Optical Reflectance, and Planar Laser Induced Fluorescence in an operando study of CO oxidation over a Pd(100) catalyst. We show that these techniques provide useful new insights such as the ability to verify that the finite region being probed by techniques such as HESXRD is representative of the sample sur

Halide perovskites have continued to rise as attractive light absorber materials, mainly driven by their potential wide applications in the fields of solar cells, photodetectors, lasers and others. However, Pb-containing perovskites are poisonous and could cause serious potential problems to our environment. Thus, there is a strong desire t

Accurate histological classification and identification of fusion genes represent two cornerstones of clinical diagnostics in non-small cell lung cancer (NSCLC). Here, we present a NanoString gene expression platform and a novel platform-independent, single sample predictor (SSP) of NSCLC histology for combined, simultaneous, histological classification and fusion gene detection in minimal formali

A study related to the separations of uranium traces in a concentrated Pu solution and plutonium traces in a concentrated U solution was performed (with Pu/U or U/Pu = 102–105). Its objective was to determine the U–Pu separation performances for a low U and Pu concentration range, namely: Pu solutions of 2.5 mg L−1 to 2.5 g L−1 containing traces of U (25 µg L−1), U solutions of 10 µg L−1 to 10 mg 

Purpose: To develop concise, patient-focussed, up to date, evidence-based, expert consensus recommendations for the management of hip and knee osteoarthritis (OA), which are adaptable and designed to assist physicians and allied health care professionals in general and specialist practise throughout the world. Methods: Sixteen experts from four medical disciplines (primary care, rheumatology, orth

Molecular hydrogen exists in two spin-rotation coupled states: parahydrogen and orthohydrogen. Due to the variation of energy with rotational level, the occupation of ortho- and parahydrogen states is temperature dependent, with parahydrogen being the dominant species at low temperatures. The equilibrium at 20 K (99.8% parahydrogen) can be reached by natural conversion only after a lengthy process

A new U–Pb baddeleyite age of 1970 ± 3 Ma for the Unoi dolerite sill of the Onega structure of Karelia craton matches other 1.98–1.95 Ga units across the Kola craton (Pechenga) and widely separated parts of the Karelian craton, including the Lake Onega sill area and a extensive NW-trending dolerite dyke swarm. Herein these coeval units are combined into the Pechenga–Onega Large Igneous Province. T

Purpose: To explore how parents of children with cerebral palsy (CP) experience their child’s participation in physical activities and to identify facilitators and barriers for being physically active and reducing sedentary behaviour. Methods: Twenty-five parents of sixteen children, aged 8–11 years old with CP, with varying gross motor, cognitive and communicative functions and with different cul

The release of toxic gases due to natural/industrial accidents or terrorist attacks in populated areas can have tragic consequences. To prevent and evaluate the effects of these disasters different approaches and modelling tools have been introduced in the literature. These instruments are valuable tools for risk managers doing risk assessment of threatened areas. Despite the significant improveme