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Radiotherapy (RT) datasets can suffer from variations in annotation of organ at risk (OAR) and target structures. Annotation standards exist, but their description for prostate targets is limited. This restricts the use of such data for supervised machine learning purposes as it requires properly annotated data. The aim of this work was to develop a modality independent deep learning (DL) model fo
For a series of biologically relevant anions, we present free energy changes upon replacing potassium with sodium in a contact ion pair. Calculations performed using a combination of molecular dynamics simulations and ab initio methods demonstrate the ordering of anions in a Hofmeister series. Small anionic groups such as carboxylates preferentially pair with sodium, while intermediate cases such
The Ordovician (∼487 to 443 Ma) ended with the formation of extensive Southern Hemisphere ice sheets, known as the Hirnantian glaciation, and the second largest mass extinction in Earth History. It was followed by the Silurian (∼443 to 419 Ma), one of the most climatically unstable periods of the Phanerozoic as evidenced by several large scale (>5‰) carbon isotope (δ13C) perturbations associated w
Background Creating new therapies often involves drug companies paying healthcare professionals and institutions for research and development (R&D) activities, including clinical trials. However, industry sponsorship can create conflicts of interests. We analysed approaches to drug company R&D payment disclosure in European countries and the distribution of R&D payments at the country
This thesis investigates the intertwining of corporate social responsibility (CSR) discourse and the European Union's strategy for sustainable and circular textiles through a single case study and critical frame analysis (CFA). By doing this, concurring discourse between corporations and the institutions aimed at governing them can be problematised. Derived from conventional and contemporary C
Cities face a host of challenges including urbanisation and climate change and must quickly adapt and integrate sustainability solutions to deal with these challenges. One platform seen as a mechanism to support innovation for sustainability in cities is the concept of the living lab. A living lab is a user-centred, open innovation ecosystem that seeks to engage academia, industry and municipaliti
New legislation involving emissions from internal combustion engines are pushing the manu-facturers to develop new technology faster than ever before with the amount of greenhouse gases. To meet the standards new concepts need to be developed with lower fuel consumption and emissions. This thesis covers the implementation of a couple of methods to achieve this. These concepts are DEP with fully va
Background and purpose: Few studies on magnetic resonance imaging (MRI) only head and neck radiation treatment planning exist, and none using a generally available software. The aim of this study was to evaluate the accuracy of absorbed dose for head and neck synthetic computed tomography data (sCT) generated by a commercial convolutional neural network-based algorithm. Materials and methods: For
Background: Chronic pain (CP) has serious medical and social consequences and leads to economic burden that threatens the sustainability of healthcare services. Thus, optimized management of pain tools to support CP patients in adjusting to their condition and improving their quality of life is timely. Although acceptance and commitment therapy (ACT) is considered an evidence-based psychological a
In the dawning age of autonomous driving, accurate and robust tracking of vehicles is a quintessential part. This is inextricably linked with the problem of Simultaneous Localisation and Mapping (SLAM), in which one tries to determine the position of a vehicle relative to its surroundings without prior knowledge of them. The more you know about the object you wish to track—through sensors or mecha
Introduction: Monitoring replacement therapy with standard and extended half-life (EHL) products is challenging, since one-stage assay (OSA) and chromogenic substrate assay (CSA) results may differ significantly. Recent recommendations include local validation of each new product with recovery within 20–30%, depending on activity level. Aim: To validate factor VIII (FVIII) activity for monitoring
This study measures the effect of competition on leverage using unbalanced panel data from 4,957 US listed firms within 8 industries. To address the issues associated with concentration indexes, we contribute to the literature by using a new measure of competition – the Boone indicator which is based on efficiency. Initially results indicate a positive (negative) effect of competition (concentrati
På grund av den snabba förändringen i det audiovisuella medielandskapet får konsumenterna och särskilt minderåriga alltmer tillgång till medieinnehåll via andra digitala plattformar än traditionella TV och video on demand tjänster. Av den anledningen är det idag mer lönsamt för företag att annonsera genom produktplacering och sponsring på plattformar för videodelning som inte regleras inom ramen fDue to the rapidly changing pace of the audiovisual media landscape, consumers and especially minors are increasingly accessing media content via other digital platforms than traditional television and on-demand services. For that reason, is it today more profitable for companies to advertise through product placement and sponsorship on video-sharing platforms which are not regulated within the sc
The master thesis seeks to develop a control system for the Crazyflie 2.0 unmanned aerial vehicle to enable aggressive and autonomous flight. For this purpose, different rigid-body models are considered, differing primarily in their parametrisation of rotation. The property of differential flatness is explored and several means of parametrising trajectories in at output space are implemented. A ne
Development of valuable products from downstream process residual biomasses and profound reduction of waste are two key components for developing a more sustainable process industry. The importance of bio-renewable feedstocks and bio-based processing techniques are also crucial in the transformation to a more sustainable and green society. Therefore focus is directed on full exploitation of seawee
In this paper, the moral duty towards asylum seekers and refugees in the EU is highlighted, from the perspectives of Universalism and Communitariarism. Due to different levels of safety and conditions related to being granted asylum in EU member states, the attractiveness of these states for asylum seekers and refugees to seek protection differ substantially. The implementation of the Dublin II Co
In order to systematize and rationalize the quality control process for FDS (Fire Dynamics Simulator) input data a software application for this specific purpose has been developed. In order to study the occurrence of user related errors in FDS input data and the possibility of reducing such errors by using the developed application, a case study on archived FDS input data from actual building pro
Variability of atmospheric circulation is considered one of the most important factors causing interannual and interdecadal variability of freshwater amount that is discharged from the continents. Here it is presented an analysis of the relations between the discharge variability of five major rivers in the Mediterranean basin (i.e. Adige, Arno Ebro, Po and Rhone) responsible for the 70% of total
Background: There is currently a steady increase in the use of wood-based fuels for heat and power production in Sweden. A major proportion of these fuels could serve as feedstock for ethanol production. In this study various options for the utilization of the solid residue formed during ethanol production from spruce, such as the production of pellets, electricity and heat for district heating, w
