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In pancreatic ductal adenocarcinoma (PDAC), the dense desmoplastic stroma and insufficient infiltrating T cells represent a significant barrier to effective immunotherapy. In this phase I, dose-escalation study, previously registered at the Dutch Trial Register and later on at ClinicalTrial (NCT05650918), we administer an autologous dendritic cell (DC) vaccine (MesoPher) with an agonistic CD40-spe
Rhesus macaques (RMs) are a vital model for studying human disease and are invaluable to preclinical vaccine research, particularly for the study of broadly neutralizing antibody responses. Such studies require robust genetic resources for antibody-encoding genes within the immunoglobulin (IG) loci. The complexity of the IG loci has historically made them challenging to characterize accurately. To
Purpose: Humoral immunity proteins—immunoglobulins, complement proteins, and antimicrobial peptides—have key antimicrobial and immunomodulatory functions in sepsis. We hypothesised that their circulating levels are lower in non-survivors, potentially resulting in impaired bacterial clearance and persistent or recurrent infections. Methods: We performed a systematic review and meta-analysis evaluat
BACKGROUND: Plasma biomarkers associated with Alzheimer's disease could improve prognostic assessment for people with Down syndrome in both clinical practice and research settings. We aimed to identify the plasma biomarkers that most accurately predict longitudinal changes in Alzheimer's disease-related pathology and cognitive functioning in individuals with Down syndrome.METHODS: This longitudina
Ninth International Conference on Hunting and Gathering Societies 1 In Defense of the Nature/Culture Distinction: Why Environmental Anthropology Can Neither Dispense With, Nor be Reduced to, Semiotics Alf Hornborg Human Ecology Division, Lund University, Finngatan 16, 223 62 Lund, Sweden Phone 46-46-2223113, Fax 46-46-2223695, Email alf.hornborg@humecol.lu.se Abstract This paper argues against the
https://projekt.ht.lu.se/fileadmin/user_upload/sol/ovrigt/projekt_ccs/Nature-Culture_Distinction.pdf - 2026-07-11
Microsoft Word - DavidD, slutversion2008.doc 57 David Petersson Förhållandet mellan anföringssats och anförd sats vid direkt anföring* Sammandrag. Vid direkt anföring uppvisar såväl anföringssats som anförd sats huvudsats- egenskaper och det är inte uppenbart hur förhållandet mellan satserna i en anförd mening ska förstås. I denna uppsats undersöks det hierarkiska förhållandet mellan anföringssats
https://projekt.ht.lu.se/fileadmin/_migrated/content_uploads/Fo__rha__llandet_.pdf - 2026-07-11
Untitled 66 AN EXPLORATORY PILOT STUDY ON PICTORIAL NARRATIVITY AND EYE SCAN PATTERNS Michael Ranta Centre for Cognitive Semiotics (CCS), Lund University, Sweden michael.ranta@semiotik.lu.se Abstract The philosophical debate on the nature of narrative has been mainly concerned with literary narratives, whereas forms of non-literary and especially pictorial narrativity have been rather neglected. W
https://projekt.ht.lu.se/fileadmin/user_upload/sol/ovrigt/projekt_ccs/IAEA_2012_MITT_FAREDRAG.pdf - 2026-07-11
1 SACO-S YRKANDEN MOT ARBETSGIVARVERKET 2025 Saco-S arbetar för att åstadkomma en långsiktigt hållbar verksamhet inom statlig sektor. Saco-S fackliga politik och arbetssätt präglas av en vilja att bidra till den statliga verksamhetens resultat och utveckling. Vi eftersträvar avtal som förändras utifrån ändrade förutsättningar och behov och avtal som stödjer ett föränderligt arbetsliv. För att möta
This is the title of my paper A longitudinal corpus of Swedish university students’ written English, some problems and some results∗ PHILIP SHAW, UNIVERSITY OF STOCKHOLM Abstract To understand how writing skills are acquired requires longitudinal studies, which should focus not only on correctness, but also on style and vocabulary development. In this project I got first-semester students in the E
https://www.sol.lu.se/fileadmin/media/forskning/workingpapers/engelska/vol04/shaw-wp-04.pdf - 2026-07-11
https://biologi.blogg.lu.se/category/mote/ - 2026-07-11
Fracture energy in birch Master’s Dissertation Structural Mechanics EMMA ESBJÖRNSSON and JOHAN SVENSSON EXPERIMENTAL TESTING OF BIRCH WOOD Fracture energy and its applicability in dowel-type joints DEPARTMENT OF CONSTRUCTION SCIENCES DIVISION OF STRUCTURAL MECHANICS ISRN LUTVDG/TVSM--24/5275--SE (1-78) | ISSN 0281-6679 MASTER’S DISSERTATION Supervisor: HENRIK DANIELSSON, Associate Professor, Divis
https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm5000/web5275.pdf - 2026-07-11
Department of Mechanical Engineering Division of Solid Mechanics ISRN LUTFD2/TFHF--04/5106--SE (1-83) ON THE INTERNAL ARCHITECTURE OF BONE BASED ON A CONTINUUM MODEL Master’s Dissertation by Zoltán Habony Supervisors Ingrid Svensson, Div. of Solid Mechanics Magnus Tägil, Dep. of Orthopaedics, Lund University Hospital Ian McCarthy, Biomechanics Laboratory, Dep. of Orthopaedics, Lund University Hosp
https://www.solid.lth.se/fileadmin/hallfasthetslara/utbildning/examensarbete/TFHF5106.pdf - 2026-07-11
Although genome-wide association studies have identified more than eighty genetic variants associated with non-small cell lung cancer (NSCLC) risk, biological mechanisms of these variants remain largely unknown. By integrating a large-scale genotype data of 15 581 lung adenocarcinoma (AD) cases, 8350 squamous cell carcinoma (SqCC) cases, and 27 355 controls, as well as multiple transcriptome and e
We have recently completed the largest GWAS on lung cancer including 29,266 cases and 56,450 controls of European descent. The goal of our study has been to integrate the complete GWAS results with a large-scale expression quantitative trait loci (eQTL) mapping study in human lung tissues (n = 1,038) to identify candidate causal genes for lung cancer. We performed transcriptome-wide association st
Background: Cardiovascular diseases (CVDs) are the leading cause of mortality and are among the foremost causes of disability globally. CVD burden has continued to increase in most countries since 1990, with trends driven by changing exposures to harmful risk factors, population growth, and population aging. Objectives: We report estimates of global, national, and subnational CVD burden, including
Objectives To conduct a comprehensive analysis of prospectively measured circulating high sensitivity C reactive protein (hsCRP) concentration and risk of lung cancer overall, by smoking status (never, former, and current smokers), and histological sub-type. Design Nested case-control study. setting 20 population based cohort studies in Asia, Europe, Australia, and the United States. ParticiPants
Background: Semantic dementia (SD) is a neurodegenerative disorder characterised by progressive language problems falling within the clinicopathological spectrum of frontotemporal lobar degeneration (FTLD). The development of disease-modifying agents may be facilitated by the relative clinical and pathological homogeneity of SD, but we need robust monitoring biomarkers to measure their efficacy. I
The comparative performance of existing models for prediction of type 2 diabetes across populations has not been investigated. We validated existing non-laboratory-based models and assessed variability in predictive performance in European populations.
