Filtyp
Among the three recently described GB viruses (GBV-A, GBV-B, and GBV-C), only GBV-C has been linked to cryptogenic hepatitis in man. Because of the limited utility of currently available research tests to determine antibody response to GBV-C proteins, the prevalence of GBV-C RNA in human sera was studied using reverse transcription-polymerase chain reaction (RT-PCR). The prevalence of GBV-C is hig
Genetic vaccines offer a treatment opportunity based upon successful gene delivery to specific immune cell modulators. Driving the process is the vector chosen for gene cargo packaging and subsequent delivery to antigen-presenting cells (APCs) capable of triggering an immune cascade. As such, the delivery process must successfully navigate a series of requirements and obstacles associated with the
Avhandlingens ämne är osannolika händelser i den realistiska romanen. Den övergripande idén är att realismen utmärks av att osannolika händelser hanteras utifrån ett dubbelt perspektiv: både som ett existentiellt och ett estetiskt bekymmer. Som ett existentiellt bekymmer representerar den narrativa fiktionsberättelsens osannolika händelser den ständigt närvarande möjligheten att en oförutsägbar ocThis thesis deals with improbable events in the realistic novel. The overarchingidea is that realism is distinguished by dealing with improbable events on thebasis of a double perspective: both as an existential and as an aesthetic problem.As an existential problem the improbable events of narrative fiction representthe constantly present possibility of an unexpected and unforeseen event suddenly
We analyzed human papillomavirus (HPV) prevalences during prevaccination and postvaccination periods to consider possible changes in nonvaccine HPV genotypes after introduction of vaccines that confer protection against 2 high-risk types, HPV16 and HPV18. Our meta-analysis included 9 studies with data for 13,886 girls and women ≤19 years of age and 23,340 women 20–24 years of age. We found evidenc
Popular Abstract in Swedish Syftet med denna studie var att (I) utvärdera sambandet mellan övervikt mätt med det s.k. body mass index (BMI) och operation med höftleds- eller knäledsprotes (konstgjord led) på grund av artros, (II) utvärdera sambandet mellan mekanisk belastning på grund av yrke och operation med höftleds- eller knäledsprotes på grund av artros, (III) utvärdera naturalförloppet för eThe purpose of this study was to (I) assess the association between body mass index (BMI) and total hip replacement (THR) and total knee replacement (TKR) due to osteoarthritis (OA), (II) assess the association between the mechanical load of work and THR and TKR due to OA, (III) evaluate the natural history of radiographic hip OA with regards to THR and hip fracture, (IV) to determine the prevalen
Vaccination against the Human Papillomavirus (HPV) has recently been approved as a means to prevent cervical cancer. The Swedish Institute for Infectious Disease Control and the Swedish Society for Obstetrics & Gynecology arranged a consensus conference to discuss design of future cervical cancer prevention programs. Conclusions include that preventive programs should aim at eradication of onc
Latent autoimmune diabetes in adults (LADA) is a special form of diabetes that is clinically similar to type 2 diabetes but with positivity for pancreatic autoantibodies. The frequency of LADA patients among all patients diagnosed as type 2 varies between 6-50% in various populations. The frequency is higher in younger age groups. It is clear, however, that the frequency of autoimmune diabetes amo
Antibiotika-resistens utgör ett ökande hälsoproblem i världen och bakterier blir alltmer resistenta mot de antibiotika vi har att behandla med. Fler bakterier blir också resistenta mot mer än ett antibiotikum och behandling av infektioner med dessa typer av bakterier kompliceras av bristen på effektiva läkemedel vilket leder till ökade sjukvårdskostnader, längre vårdtider och en minskad chans att Multi-drug resistant (MDR) infections remain the leading cause of death worldwide. MDR infections caused by Streptococcus pneumoniae (Spn), Streptococcus pyogenes (GAS) and Streptococcus agalactiae (GBS) are considered global threats to human health due to increased spread of antibiotic resistance and limited treatment options. In this thesis, we present the human milk derived HAMLET (Human Alpha-
We review the main software and computing challenges for the Monte Carlo physics event generators used by the LHC experiments, in view of the High-Luminosity LHC (HL-LHC) physics programme. This paper has been prepared by the HEP Software Foundation (HSF) Physics Event Generator Working Group as an input to the LHCC review of HL-LHC computing, which has started in May 2020.
The molecular mechanism behind affinity maturation is the introduction of point mutations in immunoglobulin (Ig) V genes, followed by the selective proliferation of B cells expressing mutants with increased affinity for antigen. An in vitro culture system was developed in which somatic hypermutation of Ig V genes was sustained in primed B cells. Cognate T cell help and cross-linking of the surface
Background: Intracoronary pressure wire measurement of fractional flow reserve (FFR) provides decision-making guidance during percutaneous coronary intervention (PCI). However, limited data exist on the effect of FFR on long-term clinical outcomes in patients with stable angina pectoris. Objectives: The purpose of this study was to determine the association between the usage of FFR and all-cause m
Classical B lymphocyte activation is dependent on BCR cross-linking in combination with physical interaction with Th cells. Other B cell molecules that contribute to the activation are complement, cytokine, and TLRs recognizing specific pathogen-associated molecular patterns. Moraxella (Branhamella) catarrhalis is a common Gram-negative respiratory pathogen that induces proliferation in human IgD-
We exploit the 7 Ms Chandra observations in the Chandra Deep Field-South (CDF-S), the deepest X-ray survey to date, coupled with CANDELS/GOODS-S data, to measure the total X-ray emission arising from 2076 galaxies at 3.5 ≤ z < 6.5. This aim is achieved by stacking the Chandra data at the positions of optically selected galaxies, reaching effective exposure times of ≥109s.We detect significant (>3.
The latest Gaia data release enables us to accurately identify stars that are more luminous than would be expected on the basis of their spectral type and distance. During an investigation of the 329 best solar twin candidates uncovered among the spectra acquired by the GALAH survey, we identified 64 such overluminous stars. In order to investigate their exact composition, we developed a data-driv
BACKGROUND: The family and friends (caregivers) of patients with advanced cancer often experience tremendous distress. Although early integrated palliative care (PC) has been shown to improve patient-reported quality of life (QOL) and mood, its effects on caregivers' outcomes is currently unknown.MATERIALS AND METHODS: We conducted a randomized trial of early PC integrated with oncology care versu
The year 2022 marked the 10th anniversary of the course Critical Animal Studies: Animals in Society, Culture and the Media at the Department of Communication and Media at Lund University. As the first initiative of its kind in Sweden, the course explores the shifting roles and positions of non-human animals in today’s complex societies. It aims to equip students with analytical tools to critically
Mantle cell lymphoma (MCL) is dependent on a supportive tumor immune microenvironment (TIME) in which infiltration of CD163+ macrophages has a negative prognostic impact. This study explores how abundance and spatial localization of CD163+ cells are associated with the biology of MCL, using spatial multiomic investigations of tumor and infiltrating CD163+ and CD3+ cells. A total of 63 proteins wer
untitled LETTERS New flutes document the earliest musical tradition in southwestern Germany Nicholas J. Conard1, Maria Malina2 & Susanne C. Münzel3 Considerable debate surrounds claims for early evidence of music in the archaeological record1–5. Researchers universally accept the existence of complex musical instruments as an indication of fully modern behaviour and advanced symbolic communicatio
https://projekt.ht.lu.se/fileadmin/user_upload/sol/ovrigt/projekt_ccs/Conard_et_al._Flutes_Nature_2009.pdf - 2026-07-11
Lundaarkeolog får ERC Synergy Grant Lundaarkeolog får ERC Synergy Grant Av Gisela Lindberg - Publicerad den 6 november 2025 Forskningsledarna efter sista intervjun i Bryssel. Från vänster: Enrico Crema, University of Cambridge, Oliver Craig, University of York, Anna Marie Prentis, University Montana och Peter Jordan, Lunds universitet. Photo credit: Oliver Craig Arkeologen Peter Jordan har tillsam
https://www.ark.lu.se/article/lundaarkeolog-faar-erc-synergy-grant/ - 2026-07-11
