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Cardiovascular disease (CVD) is the leading cause of death globally. Inflammatory cardiomyopathies can be life-threatening, and the underlying mechanisms are not fully understood. This thesis aimed to investigate the underlying mechanisms driving the pathogenesis of myocarditis and septic cardiomyopathy, and to explore potential treatment strategies. In particular, we focused on the pro-inflammato

We report the spectroscopic confirmation and fundamental properties of TOI−757 b, a mini−Neptune on a 17.5−d orbit transiting a bright star (V = 9.7 mag) discovered by the TESS mission. We acquired high−precision radial velocity measurements with the HARPS, ESPRESSO, and PFS spectrographs to confirm the planet detection and determine its mass. We also acquired space−borne transit photometry with t

Hur formulerar man ett idéhistoriskt problem? Vilken betydelse kan plats ha i idéhistoriska undersökningar? Vilka digitala verktyg kan en idéhistoriker arbeta med? Hur skiljer sig idéhistoriska undersökningar inriktade mot medicinens, filosofins, politikens och vetenskapens historia från varandra? I den här handboken ges svar på dessa och ytterligare frågor.Boken består av tre delar som behandlar

Introduction: Sepsis, a widespread global ailment, involves an exaggerated immune response, leading to hyperinflammation and immunosuppression. Extracellular histones, released during hyperinflammation as part of the defensive response against pathogens, significantly contribute to sepsis pathogenesis, compromising viability of the host’s endothelial cells and contributing to organ failure. Method

Brevmall Språk- och l i t teraturcentrum Kurslitteratur för SVE M28 Svenska: Litterär stilistik, påbyggnadskurs, 7,5 poäng Fastställd av Lärarkollegium 1 vid Språk- och litteraturcentrum, 28 november 2012. Obligatorisk facklitteratur Att anlägga perspektiv. Staffan Hellberg & Göran Rossholm (red.) Stockholm/Stehag: Brutus Östlings bokförlag Symposion. ISBN: 9171397191. 270 s. Björck, Staffan. 1953

https://www.sol.lu.se/media/utbildning/dokument/kurser/SVEM28/20131/SVE_M28KLAR.pdf - 2026-07-10

19MOD_Taking action to enhance student learning LTH:s 12:e Pedagogiska Inspirationskonferens, 7 december 2023 Abstract—A process for improving programme courses has been developed. The process has been implemented on three courses, which had reoccurring problems and/or had received significant negative criticism from students, all of which have been improved. The usefulness of the process has been

https://www.lth.se/fileadmin/cee/genombrottet/konferens2023/G1_Bagge_etal.pdf - 2026-06-09

Master’s Dissertation Structural Mechanics Report TV SM -5187 ANDREAS EDHOLM MESHING AND VISUALISATION ROUTINES IN THE PYTHON VERSION OF CALFEM Department of Construction Sciences Structural Mechanics Copyright © 2013 by Structural Mechanics, LTH, Sweden. Printed by Media-Tryck LU, Lund, Sweden, February 2013 (Pl). For information, address: Division of Structural Mechanics, LTH, Lund University, B

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm5000/web5187.pdf - 2026-07-09

Rule of Law and Access to Justice - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation of Progra

https://rwi.lu.se/fair-efficient-justice/ - 2026-07-09

Removing the Middleman: Blockchain and Human Rights - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Ev

https://rwi.lu.se/2018/04/03/blockchain-human-rights-2/ - 2026-07-09

Introduction: Streptococcus pyogenes (group A streptococcus; GAS) is a pathogen causing over half a million deaths annually worldwide. Human immune cells respond to GAS infection by activating the NLRP3 inflammasome leading to the release of pro-inflammatory cytokines that control infection. We investigated the role of C4b-binding protein (C4BP) and factor H (FH) in the inflammasome response to GA

OBJECTIVES: Esophageal cancer is a highly fatal malignant neoplasm, with 2 etiologically different histological types. A large prospective study is expected to elucidate the specific risk of the 90% subtype of esophageal cancer, esophageal squamous cell carcinoma (ESCC), with metformin therapy. This study aims to determine the association between metformin use and incident ESCC risk.METHODS: This

Arsenic is highly toxic and a significant threat to human health, but certain bacteria have developed defense mechanisms initiated by AsIII binding to AsIII-sensing proteins of the ArsR family. The transcriptional regulator AfArsR responds to AsIII and SbIII by coordinating the metalloids with three cysteines, located in a short sequence of the same monomer chain. Here, we characterize the binding

Research on the biology of the tumor stroma has the potential to lead to development of more effective treatment regimes enhancing the efficacy of drug-based treatment of solid malignancies. Tumor stroma is characterized by distorted blood vessels and activated connective tissue cells producing a collagen-rich matrix, which is accompanied by elevated interstitial fluid pressure (IFP), indicating a

RNA viruses have gained plenty of attention during recent outbreaks of Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Zika virus (ZIKV), and Ebola virus. ZIKV is a vector borne Flavivirus that is spread by mosquitoes and it mainly infects neuronal progenitor cells. One hallmark of congenital ZIKV disease is a reduced brain size in fetuses, leading to severe neurological defects. The

The feasibility to detect lactobacilli in mail-in infant stools collected monthly from 3-18 months old children was investigated. The aim was to determine total lactobacilli and Lactobacillus plantarum (L. plantarum) content (ng/g feces) in 50 infants each from Colorado (648 samples), Finland (624 samples) and Sweden (685 samples) who participated in the TEDDY (The Environmental Determinants of Di

BACKGROUND: Cytoreductive surgery with intraperitoneal chemotherapy has emerged as a new standard approach for peritoneal surface disease. This study investigated the learning curve of this combined modality treatment at a single institute.METHODS: Variables analysed over three consecutive treatment periods (1996-1998, 1999-2002 and 2003-2006) included number of abdominal regions affected, Simplif

Objectives: To compare the 1-year, 2-year and 5-year incidences of acute coronary syndrome (ACS) in patients with rheumatoid arthritis (RA) starting any of the biologic disease-modifying antirheumatic drugs (bDMARDs) currently available in clinical practice and to anchor these results with a general population comparator. Methods: Observational cohort study, with patients from Denmark, Finland, No