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Abstract in UndeterminedPurposeThe purpose of this article is to explore and classify themes and challenges in making urban freight distribution sustainable.Design/methodology/approachThe study has a cross sectional design which started by a narrative literature review and analysis of a sample of related literature (like peer-reviewed articles and EU (European Union) documents). It ended with comp
Popular Abstract in Swedish Den moderna epokens början återfinns i det sena sjuttonhundratalet och i Europa. Det är en epok, en kultur som förstår sig som både ny och som annorlunda i förhållande till tidigare epoker och kulturer, sådana som vilat på myter, religion och tradition. Den nya kulturens fundamentala insikt bestod i att ingenting måste vara så som det är, utan allt vore möjligt också påThe problem which the present study discusses is modernity. The study interprets modernity’s cultural and anthropological dispositions as historical appearances. Consequently, it is situated at the intersection of cultural sociology and historical anthropology. The aim is to generate insight and understanding rather than a coherent theory. The key element consists of combination and variation of c
We determined the frequency of extra-pair paternity and intraspecific brood parasitism in European Starlings (Sturnus vulgaris) by performing multilocus DNA fingerprinting on 22 complete families from a population in southern Sweden. Among 92 nestlings, we did not detect any successful intraspecific brood parasitism. This confirms observational data that successful intraspecific brood parasitism i
For decades, in vitro expansion of transplantable hematopoietic stem cells (HSCs) has been an elusive goal. Here, we demonstrate that multipotent adult progenitor cells (MAPCs), isolated from green fluorescent protein (GFP)-transgenic mice and expanded in vitro for >40-80 population doublings, are capable of multilineage hematopoietic engraftment of immunodeficient mice. Among MAPC-derived GFP+CD4
Aims: Skeletal muscle is a major metabolic organ and plays important roles in glucose metabolism, insulin sensitivity and insulin action. Muscle telomere length reflects the myocyte's exposure to harmful environmental factors. Leukocyte telomere length is considered a marker of muscle telomere length and is used in epidemiologic studies to assess associations with ageing-related diseases where mus
Popular Abstract in Swedish Avhandlingen ger teoretiskt, juridiskt och empiriskt stöd för att genom hjälpmedelsförsörjning öka möjligheterna för människor med funktionshinder i låginkomstländer att förverkliga sina mänskliga rättigheter och minska sin fattigdom. Människor med funktionshinder är överrepresenterade bland världens fattiga. I utvecklingsländer lever mer än hälften av dem i extrem fatDeprived of human rights, more than half of all people with disabilities in developing countries live in extreme poverty. Although considered a prerequisite for equalization of opportunities, about nine out of ten of those who need assistive technologies do not have access to them. Little is known about the socioeconomic benefits of using assistive technology in low-income countries that can infor
Mary Flannery O’Connor (1925-64) was born in Savannah, Georgia as the only child of the American Irish Catholics Edward Francis O’Connor, Jr. and Regina Cline O’Connor. In 1952 her first novel Wise Blood, in 1955 the short story collection A Good Man Is Hard to Find, and in 1960 her second novel, The Violent Bear It Away were published. She received several fellowships and titles of Honorary Docto
Background-Patients with atherosclerosis have a high risk of cardiovascular events and death. Atherosclerosis is characterized by accumulation of lipids, cells and extracellular matrix proteins in the intima. We hypothesized that dysregulated remodeling of the basement membrane proteins may be associated with clinical outcomes in patients with atherosclerosis. Methods and Results-Neoepitope fragme
Accurate determination of the genetic diversity present in the HIV quasispecies is critical for the development of a preventative vaccine: in particular, little is known about viral genetic diversity for the second type of HIV, HIV-2. A better understanding of HIV-2 biology is relevant to the HIV vaccine field because a substantial proportion of infected people experience long-term viral control,
Ectopic expression of transcription factors has been used to reprogram differentiated somatic cells toward pluripotency or to directly reprogram them to other somatic cell lineages. This concept has been explored in the context of regenerative medicine. Here, we set out to generate dendritic cells (DCs) capable of presenting antigens from mouse and human fibroblasts. By screening combinations of 1
Correct diagnosis of pulmonary tumors is essential for treatment decision and often relies on immunohistochemical markers. We stained tissue microarrays from resected primary lung cancer (n = 665) and pulmonary metastases (n = 425) for CK7, CK20, CDX2, CK5, p40, p63, TTF-1, napsin A, GATA3, and PAX8 to systematically assess the diagnostic value of these markers. Primary lung adenocarcinomas expres
Background--Exposure to cadmium has been associated with carotid plaques, inflammation in carotid plaques, and increased risk of ischemic stroke. This study examined the separate and interacting effects of blood cadmium levels and carotid plaques on the risk of incident ischemic stroke. Methods and Results--Cadmium levels were measured in 4156 subjects (39.2% men; mean ± SD age 57.3 ± 5.9 years) w
Integrin αβ heterodimer cell surface receptors mediate adhesive interactions that provide traction for cell migration. Here, we test whether the integrin, when engaged to an extracellular ligand and the cytoskeleton, adopts a specific orientation dictated by the direction of actin flow on the surface of migrating cells. We insert GFP into the rigid, ligand-binding head of the integrin, model with
In most industrial product development projects, computer-based design analysis, or simply design analysis, is frequently utilized. Several design analysis process models exist in the literature for the planning, execution and follow-up of such design analysis tasks. Most of these process models deal explicitly with design analysis tasks within two specific contexts: the context of design evaluati
