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OBJECTIVE: To evaluate the association between metformin use and incident osteoarthritis (OA) in people with diabetes and the impact of dosing. DESIGN: Nested case-control study within a cohort of >1.4 million individuals from Sweden. PARTICIPANTS: Participants were aged 35-80 years in 2005, without diabetes or OA. We identified persons with incident diabetes between 2006 and 2016 and excluded tho

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Background Insulin resistance is common in adults with obstructive sleep apnoea (OSA), yet the extent to which longitudinal metabolic improvement is driven by OSA phenotype, continuous positive airway pressure (CPAP) treatment, or changes in body weight remains unclear. We examined 1-year changes in insulin resistance across OSA and non-OSA subgroups in the non-diabetic RICCADSA cohort. Methods In

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Pyrolytic carbon derived from thermosetting polymer precursors is a promising electrode material for bioelectrochemical applications due to its structural robustness, chemical stability, biocompatibility, and amenability to surface modification. Crucially, it allows the integration of diverse nano- and microstructures on the electrode surface. In this study, we introduce pyrolytic carbon nanograss

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INTRODUCTION: Perineal hernia is a protrusion of the pelvic floor containing intra-abdominal viscera. The occurrence of postoperative perineal hernia after abdominoperineal resection (APR) is rare, but reports have indicated a recent increase in occurrence following surgical treatment for rectal cancer. This has been attributed to a shift towards extralevator abdominoperineal resection, together w

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Östersjön har stora problem med övergödning, eutrofiering, vilket beror på en ökad transport av näringsämnen från omgivande länder. Näringen kommer främst i form av kväve och fosfor från jordbruket och transporteras ut i Östersjön via floder. Framförallt kväve har stor påverkan på övergödningen, som i sin tur leder till fiskdöd, algblomning och syrefria bottnar i sjöar. I den här studien ska läckEutrophication problems in the Baltic Sea have drawn attention to the contribution of nutrients from surrounding countries. The problems have attracted considerable attention to non-point source nitrogen pollution of rivers and lakes. The ability to predict nitrogen export from inland sources is essential in order to evaluate the effects of anthropogenic activities, of which the leakage from agric

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The primary purpose of this thesis is to analyze how the US unemployment rate affects the US market and markets overseas, the latter called spill over effects. Indications of market inefficiency are also analysed. Our expectations are that unanticipated unemployment rate should affect stock markets, especially small, dependant markets like the Swedish. Also we expect that lower than expected unemp

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In February 2000 the Commission of the European Community presented the long awaited White Paper on Environmental Liability. The White Paper outlines the key elements for a future directive on environmental liability, covering contaminated soil and subsoil, water pollution and damage to biodiversity. The directive will be a framework regime containing essential minimum requirements to be completed

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This thesis addresses the right to education and its implementation. It briefly assesses the right to education while focussing on the right to primary education. The implementation of human rights as stated in international instruments can meet with hindrance in the form of cultural relativist arguments as well as resistance on pragmatic grounds. The case study carried out in Tanzania aims at ass

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Climate change is a threat facing the planet which could bring disastrous consequences. In the globalised world, states are less capable of fighting this threat alone&semic it is also necessary that companies take on this challenge. Amongst other people, this idea is supported by Kofi Annan and Nicolas Stern. One of the ways in which this is done is through Corporate Social Responsibility (CSR

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This thesis investigates how members of the Danish Naturalisation Committee navigate, exer-cise, and justify their discretionary power in exemption cases, and what this reveal about the intersection of law, politics, and affect in the governance of citizenship. While most countries treat naturalisation as an administrative procedure, Denmark stands out: citizenship is granted by parliamentary law,

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This research analyses the communication strategies of the Israeli Defence Forces (IDF) and Hamas’ Al-Qassam Brigades on Telegram following the October 7th, 2023, attack. Focusing on 40 images and videos posted between October and December 2023, it investigates how visual content is used to perform violence, shape narratives, and legitimise actions. The study adopts a qualitative, social construct

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Introduction: A Natural Deep Eutectic Solvent (NaDES) is presumably a green and cost-effective eutectic solvent, capable of extracting many different types of analytes. The analyte, apigenin, is a potential nutraceutical compound with anti-diabetic properties. Background: NaDES compositional variation and unknown properties challenges prediction of their extraction selectivity. Aim(s): Correlate N

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Den nya AI-boomen sänker kraftigt kostnaden för att bygga mjukvara, snabbar på imitationen och intensifierar konkurrensen inom Software as a Service (SaaS), vilket pressar betalningsviljan mot noll. Denna studie ställer två frågor: (1) vilka affärsmodellsinnovationer och utmaningar kännetecknar monetarisering av gratis digitala tjänster, och (2) hur kan dessa insikter tillämpas på ScanThisWine, etThe new AI-boom dramatically lowers the cost of building software, accelerates imitation, and intensifies competition in Software as a Service (SaaS), pushing willingness to pay towards zero. This study asks two questions: (1) which business model innovations and challenges characterise the monetisation of free digital services, and (2) how can these insights apply to ScanThisWine, a free e-label

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The rapid advancements of Artificial Intelligence (AI) in recent years have reshaped markets globally, urging companies to keep up with the development to maintain competitiveness and capture first-mover advantages. Although AI adoption is increasing across sectors, it has been found that Swedish companies lag behind other countries, such as the US and China. A key challenge identified is the lack

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Art funds are gaining traction as an alternative asset class, yet investors must often weigh financial returns against ethical objectives such as promoting diversity in the art market. This bachelor’s thesis investigates how these two motives interact by asking: How do ethical and financial drivers shape individual investors’ willingness to allocate capital to art funds? A two-part online survey

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This thesis examines how national identity influenced Swedish and Danish diplomatic strategies within the European Free Trade Association (EFTA) from 1960 to 1962, and how these strategies were portrayed in national newspapers. By applying a theoretical framework focused on interpreting diplomatic intentions, alongside a narrative analysis of news articles, the study scrutinises EFTA documents and

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In recent years, tyre wear particles (TWPs) have been included in the discussions regarding air pollution, which is a growing global concern. Although exhaust emissions have been extensively studied and are being reformed towards better alternatives, there is still a wide knowledge gap regarding non-exhaust emissions such as TWPs. Most studies regarding TWPs focus on microplastics environmental co

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Sweden restructured its asylum reception system in 2025, shifting from a model that allowed asylum seekers to arrange their own accommodation towards one that encourages residence in centrally managed facilities operated by the Swedish Migration Agency. This study examines how the location of eleven reception centres operating after the reform affects asylum seekers’ well-being and integration out

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This thesis examines whether the transfer of a company containing accumulated retained earnings to a shareholder benefiting from a more favourable dividend tax regime can constitute a form of structural dividend stripping under EU law. Unlike traditional dividend stripping arrangements, such as cum-ex and cum-cum transactions, these structures rely on intra-group corporate restructurings through w

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Den föreliggande studien syftade till att undersöka i vilken utsträckning schematisk extrinsisk kongruensnivå (kongruent, neutral och inkongruent) hos icke-presenterade rumsobjekt och exponeringstid (4 sekunder och 10 sekunder) för rumsbilder påverkade nivåer av falsk minnesbildning. Ett faktoriellt experiment med upprepade mätningar genomfördes med ett urval bestående av 102 svenska deltagare i åThe present study aimed to examine the extent to which schematic extrinsic congruence level (congruent, neutral, and incongruent) of non-present room objects and exposure time (4 seconds and 10 seconds) of room images influenced levels of false memory formation. A factorial repeated-measures experiment was conducted with a sample consisting of 102 Swedish participants aged 18–35 years. The experim