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Background High-dose aspirin (>= 500 mg daily) reduces long-term incidence of colorectal cancer, but adverse effects might limit its potential for long-term prevention. The long-term effectiveness of lower doses (75-300 mg daily) is unknown. We assessed the effects of aspirin on incidence and mortality due to colorectal cancer in relation to dose, duration of treatment, and site of tumour. Methods
Background The influence of familial factors on the prognosis of heart failure (HF) is unknown. This nationwide follow‐up study aimed to determine familial mortality risks of HF among Swedish siblings hospitalized for HF. Methods and Results We linked several Swedish nationwide registers for individuals aged 0 to 80 years. The study population consisted of 373 people hospitalized for HF for the
Pain, use of painkillers and alcohol are highly prevalent in the general population. Aims of the study were to describe differences in pain, alcohol consumption and use of painkillers among two 60 year old birth cohorts stratified by gender. Participants were recruited from the Skåne centre of The Swedish National study on Aging and Care, a multicentre, prospective, longitudinal study. The sample
Here we describe an in vitro co-culture system that can differentiate hematopoietic progenitor populations to all major hematopoietic lineages at clonal level. We present both a sensitive single-cell switch-culture system as well as a less laborious alternative barcoding protocol more convenient for larger cell numbers. Importantly, generation of all lineages from single long-term hematopoietic st
Brevmall Konstnär l iga fakulteten i Malmö Disputation och examen inom forskarutbildning Intern arbetsordning vid Konstnärliga fakulteten, Lunds universitet. Generellt gäller att institutionen ansvarar för praktiska frågor och fakultetskansliet ansvarar för formella beslut och övergripande samordning samt som stöd i processen. För detaljer se appendix samt i förekommande fall detaljerad info för r
https://www.konstnarliga.lu.se/sites/konstnarliga.lu.se/files/disputation_och_examen_vid_konstnarliga_fakulteten.pdf - 2026-07-20
The Wilms tumor gene (WT1) encodes a zinc-finger containing transcription factor present in primitive hematopoietic progenitor cells. WT1 is also highly expressed in most cases of acute myeloid leukemia. Moreover, WT1 can interfere with induced differentiation of leukemic cell lines. These data suggest a function of WT1 in the maintenance of a primitive phenotype and a role in leukemogenesis by in
We review the history of floristic studies of the parish of Stenbrohult, southern Sweden, where Carl Linnaeus was born in 1707 and spent his summers until 1728. Unfortunately, Carl Linnaeus never made a list of the wild vascular plants at his birthplace, although he mentioned at least 64 species from the parish of Stenbrohult in various manuscripts and books. However, he said that Stenbrohult was
Transplantation of hematopoietic stem cells (HSCs) to treat hematological disorders is routinely used in the clinic. However, HSC therapy is hindered by the requirement of finding HLA-matched donors, as well as attaining sufficient numbers of long-term HSCs in the graft. Therefore, ex vivo expansion of transplantable HSC remains one of the "holy grails" of hematology. Without the ability to mainta
Optogenetic techniques provide powerful tools for bidirectional control of neuronal activity and investigating alterations occurring in excitability disorders, such as epilepsy. In particular, the possibility to specifically activate by light-determined interneuron populations expressing channelrhodopsin-2 provides an unprecedented opportunity of exploring their contribution to physiological and p
Importance Active perinatal care increases survival of extremely preterm infants; however, improved survival might be associated with increased disability among survivors. Objective To determine neurodevelopmental outcome in extremely preterm children at 2.5 years (corrected age). Design, Setting, and Participants Population-based prospective cohort of consecutive extremely preterm infants born be
Objectives: Ventilator-associated pneumonia (VAP) is difficult to diagnose using clinical criteria and no biomarkers have yet been proved to be sufficiently accurate. The use of the neutrophil-derived Heparin-binding protein (HBP) as a biomarker for pneumonia was investigated in this exploratory case–control study in two intensive care units at a tertiary referral hospital. Methods: Patients with
Popular Abstract in Swedish Shusaku Endo (1923-1960) är en romersk-katolsk, japansk romanförfattare. Från 1950-1953 studerade han fransk litteratur I Lyon, Frankrike. När han återvänt från Lyon, började Endo en karriär som författare. Hans tidiga verk omfattar bl a White Men, Yellow Men (1954) Wonderful Fool (1959), The Women in the Bible (1960),Foreign Studies (1965). Denna studie analyserar hanShusaku Endo (1923-1996) is a Roman Catholic, Japanese novelist. From 1950 to 1953, he studied French literature in Lyon, France. Returning from Lyon, Endo began his career as a novelist. His early works include: White Men, Yellow Men(1954), A Wonderful Fool(1959), The Women in the Bible(1960), Foreign Studies(1965), etc. The present study analyses his work from the perspective of the inculturati
En studie om sökta och erhållna belöningar genom användning av Enterprise Social Media: ett medarbetarperspektiv Många anser att ESM har potentialen att både förenkla och förbättra samarbete, och stärka det ”sociala kapitalet”, men ändå misslyckas 80% av implementationerna. Denna studie hoppas ge insikter i vad som driver de som ändå använder ESM, med förhoppningen att bidra till fler lyckade fraA study of the gratifications sought and obtained through using Enterprise Social Media: an employee perspective Although ESM is widely held to have the potential to improve both collaborative efficiency and to strengthen social ties among employees, around 80% of ESM implementations fail. This study aims to provide a clearer understanding of why some people do use ESM, which in turn can lead to
