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Electrophysiological and pharmacological properties of neurons within solid basal forebrain transplants were studied in adult rats anesthetized with urethane. No specific topography of the neurons recorded was observed within the graft. The mean spontaneous activity of the grafted neurons (GNs) was relatively low (4.9 impulses/s) but not unlike that of other central neurons in situ. A large propor
The Chinese-led Asian Infrastructure Investment Bank (AIIB) started operation in January 2016 in the context of severe criticism from the U.S. government and transnational civil society organizations, but with the support from major Asian and European states. The establishment of this new global governance institution (GGI) raises intriguing questions concerning legitimacy and (de)legitimation. Wh
We review our recent studies of excited state structures and dynamics of chemical and biological systems with pico- and femtosecond X-ray absorption spectroscopy in the liquid phase.
This paper presents a qualitative questionnaire study of brand-specific visual product design in the automotive sector. The purpose of the study was to explore the visual product experience of automobile design as perceived by the general public and to analyse those experiences using an emerging framework for visual product experience; VPE. In the study; respondents were asked to assess the design
This paper reports the main results of an experimental study on the mechanics of intensely fissured natural clays, extending our previous studies on scaly clay from Santa Croce di Magliano. While previous work focused on the influence of the orientation of fissures with respect to the loading direction, the present investigation specifically explores an additional, important variable: the stress l
Background: The mechanisms by which exposure to particulate matter might increase risk of cardiovascular morbidity and mortality are not fully known. However, few existing studies have investigated the potential role of particle radioactivity. Naturally occurring radionuclides attach to particulate matter and continue to release ionizing radiation after inhalation and deposition in the lungs. We h
This issue of the AILA Review focuses on transdisciplinarity as the key to developing shared languages in and across domains and professional settings. The relationship and collaboration between researchers and practitioners have long been discussed within and across applied sciences and theoretical disciplines, mainly in the framework of transdisciplinarity (see AILA Review 31, 2018, for a recent
This paper begins by explaining Philip Lewis’s key contribution to the development of legal professions studies, culminating in the three volume comparative work Lawyers in Society to which he contributed and co-edited with Rick Abel [(1988a) Lawyers in Society: Vol I The Common Law World (Berkeley, University of California Press); (1988b) Lawyers in Society: Vol II The Civil Law World (Berkeley,
Preclinical studies have suggested that epigenetic therapy could enhance immunogenicity of cancer cells. We report the results of the PEMDAC phase 2 clinical trial (n = 29; NCT02697630) where the HDAC inhibitor entinostat was combined with the PD-1 inhibitor pembrolizumab in patients with metastatic uveal melanoma (UM). The primary endpoint was objective response rate (ORR), and was met with an OR
During the last few decades, education globally has been marked by being closely related to the economy. It always was, but today’s commodification and marketization reach into any aspect of the educational system (Ball, 2012; Bartlett et al., 2002). Sweden is a specific case at hand, since privatization and competition between schools have taken especially sinister forms, and have far-reaching ef
Objectives: This study was performed to investigate the protective effects of taurine (2-aminoethanesulfonic acid, TAU) on oxidative stress in the isolated mouse testicular mitochondria, mitochondrial membrane potential (MMP), viability and motility of the exposed sperms to the BPA. Methods: We treated epididymal spermatozoa obtained from mice and isolated mouse testicular mitochondria with BPA (0
Conservative opponents of monastic reform in the tenth and eleventh centuries have traditionally been portrayed as principally reluctant to change and unwilling to abandon privileges and preferential treatment. This article performs a close, comparative reading of the poem Carmen ad Rotbertum regem by Adalbero of Laon (c.950–1031) and the monastic chronicle Casus Sancti Galli by Ekkehard IV (c.980
PurposeArchitectural theorists have a long tradition of acknowledging the centrality of building users to architectural production. This article contributes to the discourse on architecture, actor–network theory (ANT), and users by proposing a typology of user translations ranging from supporting to tinkering to adjusting to resisting.Design/methodology/approachThe research utilises an ANT-inspire
In this paper, a novel multi-region Eulerian model is presented to study the conversion of thermally thick biomass particles. In the present model, the particle and the surrounding fluid are treated as two separate regions that are coupled through an interface. There are some benefits for using a multi-region approach, including a more realistic radiation modeling, flexibility to define the flow b
In this report we describe the first two US patients with congenital disorder of glycosylation type Ig (CDG-Ig). Both patients presented with symptoms indicating CDG, including developmental delay, hypotonia and failure to thrive, and tested positive for deficient glycosylation of transferrin. Labeling of the patients' lipid-linked oligosaccharides suggested mutations in the hALG12 gene, encoding
The Krapperup drill core from Scania (Skåne), southern Sweden, includes one of the most important graptolitic Darriwilian (upper Middle Ordovician) successions of Baltica. Only some intervals have been documented previously and especially the uppermost part of the succession has been completely unknown. A fairly complete succession of mid- to late Darriwilian age provides insight into the early ev
utoradiography is defined as technologies and methods used to produce a two-dimensional image of the distribution of activity in, or on, a thin and solid sample that is in close proximity to the detector. The images are usually formed by charged particles (α or β±), and image characteristics are determined both by the detector and the properties of the particles detected. This method is not widely
