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BACKGROUND: Advanced glycation end products (AGE) and their receptors (RAGE) have been implicated in cancer development through their proinflammatory capabilities. However, prospective data on their association with cancer of specific sites, including pancreatic cancer, are limited.METHODS: Prediagnostic blood levels of the AGE product Nε-(carboxymethyl)lysine (CML) and the endogenous secreted rec
Traditionally, when optimizing base-stock levels in spare parts inventory systems, it is common to base the decisions either on a linear shortage cost or on a certain target fill rate. However, in many practical settings the shortage cost is a non-linear function of the customer waiting time. In particular, there may exist contracts between the spare parts provider and the customer, where the prov
Swedish and international research indicate that many measures made by social services, concerning children and adolescents who are taken from their homes to an institution, are interrupted prematurely for different reasons. The word "breakdown" is used when a measure granted by the social service is broken before the projected time has passed. Research concerning how social service empl
Diffusion MRI uses the random displacement of water molecules to sensitize the signal to brain microstructure and to properties such as the density and shape of cells. Microstructure modeling techniques aim to estimate these properties from acquired data by separating the signal between virtual tissue 'compartments' such as the intra-neurite and the extra-cellular space. A key challenge is that th
I denna rapport redovisas populationstrender för 178 svenska fågelarter för åren 1975–2013. Fåglarna har räknats på vintern och på sommaren enligt strikt standardiserade metoder. Sommar- respektive vinterpunktrutter har räknats sedan 1975, i huvudsak i södra Sverige. Standardrutterna räknas också på sommaren (sedan 1996) men täcker hela Sverige. Vintern 2012/2013 räknades 130 000 fåglar av 128 artWe present the results of the Swedish Bird Survey, run by the Department of Biology, Lund University, as a part of the National Monitoring Programme of the Swedish Environmental Protection Agency. The results for 2013 include data from 580 winter point count routes in 2012/2013 (38th winter), of which 295 were carried out during the Christmas/New Year count and 273 summer point count routes (39th
The mechanisms and role of nerve cell death after traumatic brain injury (TBI) are not fully understood. The authors investigated the effect of pretreatment with the oxygen free radical spin trap alpha-phenyl-N-tert-butyl-nitrone (PBN) on the number of neurons undergoing apoptosis after TBI in rats. Apoptotic cells were identified by the TUNEL method combined with the nuclear stain, Hoechst 33258,
Agroforestry systems, which incorporate trees into agricultural land, could contribute to sustainable agricultural intensification as they have been shown to increase land productivity, biodiversity and some regulating ecosystem services. However, the effect of temperate agroforestry systems on pest control and pollination services has not been comprehensively reviewed, despite the importance of t
BACKGROUND: Increasing life expectancy for people with an intellectual disability (ID) is resulting in more persons with cancer and a greater need for end-of-life (EoL) care. There is a need for knowledge of health care utilisation over the last year of life to plan for resources that support a high quality of care for cancer patients with ID. Therefore, the aims of the study were to compare (1) h
Recent years has seen a growth of so-called ”Al-Qaeda franchises”, terrorist groups who formally ally with Al-Qaeda. This study investigates the phenomenon through how one such actor, the “Salafist Group for Preaching and Combat” (GSPC), has developed after its alliance with Al-Qaeda in 2006 and rebranding as ”Al-Qaeda in the Islamic Maghreb” (AQIM). By analyzing GSPC before and after the alliance
Syftet med studien är att undersöka hur fastighetsbolag arbetar med tjänster och digitala lösningar som ökar kundnyttan i kontorsfastigheter fastigheter. Studien syftar även till att undersöka vilka tjänster och digitala lösningar som hyresgästerna sannolikt kommer att efterfråga i framtiden. Studien har genomförts både som kvalitativ studie genom fallstudie av sex av Sveriges 25 största fastighet
Design, as a principal function for innovation in business, governments, and other social units, can play a critical role in creating sustainable solutions. While current debates acknowledge expanding design scope and continuing competencies that distinctively qualify design professionals for undertaking sustainability challenges, design schools in higher education institutions are struggling to m
As the world’s fifth largest oil producer, and holder of the third largest proven oil reserves, Canada is poised to significantly impact future global carbon emissions. The present government, under the leadership of Liberal Prime Minister Justin Trudeau, is seeking to simultaneously position itself as a global climate leader while supporting the exploitation of Canada’s extensive bitumen oil rese
The production and use of chemicals has grown exponentially over the past 50 years. Although the knowledge of hazards and risks associated with chemicals towards humans and the environment has increased, we know frightenedly little about how dangerous these might become when part of finished products. Companies now need to be more concerned about which chemicals exist in their products. For the co
This report looks at the interface between pre-planned operational/contingency plans and their users. It takes in concern the importance of keeping plans up to date, the value of a uniform design of the plans and the need for continuous education and training of personnel among other things.
Through Laclau and Mouffe’s discourse theory, I analyse how the Sweden Democrats fixate the parliamentary discourse on immigration. Also, I investigate what the other parties’ role are is in this fixation, and how they can limit the Sweden Democrats’ influence over the discourse. My material consists of parliamentary debates from 2010 to 2012. My main conclusions are that the Sweden Democrats dest
Boilerplate är en term som används för att beskriva standardiserade klausuler som ofta återfinns i slutet av ett avtal och som behandlar generella frågor som inte är beroende av avtalets art eller omfattning. Det finns flertalet olika boilerplate, varav en är integrationsklausulen. Klausulen har i och med internationaliseringen av den kommersiella rätten blivit mycket vanligt förekommande i svenskBoilerplate is a term used to describe standardized clauses that often appear at the end of a contract and deals with general issues that are not dependent on the nature or scope of the agreement. There are several different boilerplates, one of which is the entire agreement clause. The entire agreement clause has become very common in Swedish law due to the internationalization of Swedish busines
Background: Treatment with antihypertensives in patients with advanced cancer is often continued until very late in the disease trajectory, despite a considerable risk of hypotension. Objectives: The aim of this study was to investigate the time of deprescribing of antihypertensive agents in patients with cancer receiving palliative care during their last year of life. The monitoring of blood pres
Ferroelectric thin films present a powerful platform for next-generation computing and memory applications. However, domain morphology and dynamics in buried ferroelectric stacks have remained underexplored, despite their importance for real device performance. Here, nanoprobe X-ray diffraction (nano-XRD) is used to image ferroelectric domains inside BiFeO3-based capacitors, revealing local disord
