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HCCI (Homogeneous Charge Compression Ignition) is a very control-intensive combustion concept which has been studied for over a decade because of its favorable combination of high efficiency and low emissions. Various optimal control methods have been applied to HCCI and this chapter gives an overview of them. Optimal control of HCCI can be divided into model based and non-model based where MPC is
Partially premixed combustion is a compression ignited combustion strategy where high exhaust gas recirculation (EGR) levels in combination with early or late injection timing result in a prolonged ignition delay yielding a more premixed charge than with conventional diesel combustion. With this concept it is possible to get low smoke and NOx emissions simultaneously. Accurate control of injection
Previous research carried out by the authors described the role of dual-fuel combustion efficiency on overall engine efficiency at high diesel substitution ratio. At low loads, high diesel substitution ratios result in excessive total unburned hydrocarbon emissions due to bulk flame quenching, and consequently lower substitution ratios in combination with intake air heating, throttling and increas
The effects of fuel properties on the performance and emissions of an engine running in partially premixed combustion mode were investigated using nine test fuels developed in the gasoline boiling point range. The fuels covered a broad range of ignition quality and fuel chemistry.The fuels were characterized by performing a load sweep between 1 and 12 bar gross IMEP at 1000 and 1300 rpm. A heavy d
It is tractable to increase the torque for an HCCI engine and one way is to add a turbocharger. Operating in HCCI mode requires accurate control of the combustion phasing, CA50. The higher the engine torque, the narrower the CA50 window becomes where HCCI operation is maintained. As the CA50 varies stochastically between cycles this requires improved CA50 control for turbo HCCI engines. The main f
STUDY QUESTION: What is the relationship between the number of oocytes collected in fresh IVF treatments and the likelihood of cumulative delivery rate (fresh and frozen) per oocyte aspiration, severe ovarian hyperstimulation syndrome (OHSS) and thromboembolic events? SUMMARY ANSWER: Cumulative delivery rate per aspiration increases up to 20 oocytes retrieved and then evens out while the incidence
Partially premixed combustion aims to reduce NOx and particulate matter emission without fuel consumption penalty. Low temperature reactions are important for the partially premixed combustion. In the current study, a self-adaptive strategy is introduced to predict the motoring pressure by means of an equivalent isentropic index. The start of the low temperature reactions is detected when the pres
BACKGROUND: Timely assessment of the burden of HIV/AIDS is essential for policy setting and programme evaluation. In this report from the Global Burden of Disease Study 2015 (GBD 2015), we provide national estimates of levels and trends of HIV/AIDS incidence, prevalence, coverage of antiretroviral therapy (ART), and mortality for 195 countries and territories from 1980 to 2015.METHODS: For countri
Mitochondrial disease refers to a heterogeneous group of disorders resulting in defective cellular energy production due to dysfunction of the mitochondrial respiratory chain, which is responsible for the generation of most cellular energy. Because cardiac muscles are one of the high energy demanding tissues, mitochondrial cardiomyopathies is one of the most frequent mitochondria disorders. Mitoch
PURPOSE:: To investigate concordance between objective and perceived neighborhood walkability, their associations with self-reported walking and objective physical activity, and sociodemographic characteristics of individuals in neighborhoods with objectively assessed high walkability who misperceive it as low. METHODS:: In 1,925 individuals aged 20-66 years, recruited from administrative areas in
Huntington disease (HD) is a fatal neurodegenerative disorder caused by an expanded CAG repeat. Its length can be used to estimate the time of clinical diagnosis, which is defined by overt motor symptoms. Non-motor symptoms begin before motor onset, and involve changes in hypothalamus-regulated functions such as sleep, emotion and metabolism. Therefore we hypothesized that hypothalamic changes occ
Generative AI promises substantial productivity gains, but many initiatives fail. This column argues that outcomes depend on readiness, not technology alone. We examine AI transformation requirements across organizational, individual, and technological dimensions, highlighting why engineering practices, human factors, and strategic clarity determine success.
Background: Heart diseases are among the leading causes of disease burden worldwide with often a large impact on the lives of the affected individuals. The association between heart disease and depression is well-known and elevated suicide risk has been demonstrated in several types of heart disease. The aim of this study was to investigate what health care contacts individuals with heart disease
Carefully selecting the source data is crucial to achieve high performance of transfer learning methods for brain–computer interfaces (BCIs). Especially so in settings where a large amount of source data is available, and finding the optimal source is not computationally feasible. This paper presents a novel method for source selection, the so-called Transfer Performance Predictor (TPP) method. Th
INTRODUCTION: Resection of intraductal papillary mucinous neoplasm (IPMN) aims to prevent progression to invasive pancreatic cancer. However, the risks of pancreatic surgery and frequent findings of low-grade dysplasia (LGD) raise concerns about overtreatment. This EAHPBA-endorsed multinational study evaluated short- and long-term overall survival (OS) following preventive resection for IPMN (with
Background: Limited evidence exists for effect modification of genetic characteristics on the associations of food consumption and incident type 2 diabetes (T2D). Objectives: We aimed to investigate whether the food-T2D association would vary by genetic susceptibility to metabolic traits. Methods: We analyzed data from 9542 incident T2D cases and a subcohort of 12,477 participants nested within th
Although 6G is not only about higher data rates, its envisioned peak data rate of 1 terabits per second requires larger frequency bandwidth than what 5G millimeter wave bands offer. Therefore, new frequency bands have been allocated in the sub-THz range for 6G applications. This paper reviews the concept of distributed deployment to provide coverage in sub-THz bands, focusing on the design and imp
