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Mitochondrial disease refers to a heterogeneous group of disorders resulting in defective cellular energy production due to dysfunction of the mitochondrial respiratory chain, which is responsible for the generation of most cellular energy. Because cardiac muscles are one of the high energy demanding tissues, mitochondrial cardiomyopathies is one of the most frequent mitochondria disorders. Mitoch

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Plasma biomarkers that reflect molecular states of the cardiovascular system are central for clinical decision making. Routinely used plasma biomarkers include troponins, natriuretic peptides, and lipoprotein particles, yet interrogate only a modest subset of pathways relevant to cardiovascular disease. Systematic profiling of a larger portion of circulating plasma proteins (the plasma proteome) w

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PURPOSE:: To investigate concordance between objective and perceived neighborhood walkability, their associations with self-reported walking and objective physical activity, and sociodemographic characteristics of individuals in neighborhoods with objectively assessed high walkability who misperceive it as low. METHODS:: In 1,925 individuals aged 20-66 years, recruited from administrative areas in

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Background: Heart diseases are among the leading causes of disease burden worldwide with often a large impact on the lives of the affected individuals. The association between heart disease and depression is well-known and elevated suicide risk has been demonstrated in several types of heart disease. The aim of this study was to investigate what health care contacts individuals with heart disease

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Background: Limited evidence exists for effect modification of genetic characteristics on the associations of food consumption and incident type 2 diabetes (T2D). Objectives: We aimed to investigate whether the food-T2D association would vary by genetic susceptibility to metabolic traits. Methods: We analyzed data from 9542 incident T2D cases and a subcohort of 12,477 participants nested within th

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Although 6G is not only about higher data rates, its envisioned peak data rate of 1 terabits per second requires larger frequency bandwidth than what 5G millimeter wave bands offer. Therefore, new frequency bands have been allocated in the sub-THz range for 6G applications. This paper reviews the concept of distributed deployment to provide coverage in sub-THz bands, focusing on the design and imp

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In this paper, we propose the design of a roof-glass integrated microstrip antenna for vehicular SDARS tuners. The proposed microstrip antenna is sandwiched inside a multi-layer roof glass and uses a solar-heat reduction coating on the bottom side of the glass as ground plane. To offset the effect of the lossy glass, parasitic elements are added to enhance the antenna gain. Simulation results show

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In multi-user multiple-input multiple-output (MU-MIMO) systems, the non-linear behavior of the power amplifiers (PAs) may cause degradation of the linear precoding schemes dealing with interference between user equipments (UEs), e.g., the zero-forcing (ZF) precoder. One way to minimize this effect is to use digital-pre-distortion (DPD) modules to linearize the PAs. However, using perfect DPD modul

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This paper proposes a D-band patch antenna featuring four parasitic elements and a loaded superstrate layer. Inspired by a previous parasitic patch antenna design, the new structure is synthesized from scratch using characteristic mode analysis. The new design features different operating principles that enable low-cost single-layer fabrication on PCB HDI technology, while retaining wideband opera

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The remarkable advances in AI and Large Language Models (LLMs) have enabled machines to write code, accelerating the growth of software systems. However, the bottleneck in software development is not writing code but understanding it; program understanding is the dominant activity, consuming approximately 70% of developers' time. This implies that improving existing code to make it easier to under

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This letter proposes a novel wideband, single-layer monopolar antenna with high selectivity and enhanced pattern stability across the operating band. Building upon a conventional circular patch antenna, the rejection levels of the upper and lower sidebands are carefully analyzed, designed, and optimized to achieve the desired performance. To further improve performance, a shorting-via-loaded ring

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5G antennas for vehicular connectivity are often mounted on the car roof to optimize signal reception. The trend of replacing metal roof with glass in modern cars opens an opportunity for embedding the 5G antennas inside the glass roof. In this work, we compare the channel gains of reference dipole, and loop antennas positioned at the roof center. Then, by considering the requirements of glass int

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The spectrum of frontotemporal dementia/amyotrophic lateral sclerosis (FTD/ALS) and Huntington disease (HD) are fatal neurodegenerative disorders with no major disease-modifying therapies. Recent work has shown that the hallmark pathological proteins TAR DNA binding protein of 43 kDa (TDP-43) in FTD/ALS and mutant huntingtin (mHTT) in HD may be interlinked. Furthermore, these disorders share early

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We describe a system for automatic annotation of English text in the FrameNet standard. In addition to the conventional annotation of frame elements and their semantic roles, we annotate additional semantic information such as support verbs and prepositions, aspectual markers, copular verbs, null arguments, and slot fillers. As far as we are aware, this is the first system that finds this informat

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Popular Abstract in Swedish SAMMANFATTNING PÅ SVENSKA Grupp B streptokocker (GBS) Grupp B streptokocker (GBS), på latin Streptococcus agalactiae, är det vanligaste fyndet vid bakteriella infektioner, som blodförgiftning (sepsis), hjärnhinneinflammation (meningit) och lunginflammation (pneumoni) hos nyfödda barn. Sjukdomsförloppet är ofta våldsamt och livshotande. Sedan 1970-talet har det skett enABSTRACT Streptococci constitute a heterogeneous group of Gram-positive bacteria, divided into different serological groups on the basis of antigenic differences in a cell wall-associated carbohydrate. This thesis describes related surface proteins expressed by bacteria in two of these groups, the group B streptococcus (GBS) and the group A streptococcus (GAS). GBS is an encapsulated bacterium th

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IMPORTANCE Fluid overload occurring as a consequence of overly aggressive fluid resuscitation may adversely affect outcome in hemodynamically unstable critically ill patients. Therefore, following the initial fluid resuscitation, it is important to identify which patients will benefit from further fluid administration. OBJECTIVE To identify predictors of fluid responsiveness in hemodynamically uns

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This thesis focuses on the exchange of experience, knowledge and strategies between local social movements resisting large scale mining projects. While the exchanges between local movements and supralocal movements, international organizations and NGOs has been studied, less attention is payed to the role of collaborations between local movements themselves. A case study based on fieldwork and int

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Iron is an important material in the study of societies of the Iron Age and later periods. Not only does it give its name to the period it was also an integrated part in every humans’ life from the Iron Age and forward. And yet this material is many times just assumed to be there without much consideration of how it got there. In this master thesis, the author thus tries to bridge this gap in betw

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The fashion industry is one of the largest contributors to environmental issues and has a significant part of plastic production due to the use of synthetic fibres. Much scientific research indicates that the fast fashion model is a significant part of using synthetic fibres; however, slow fashion brands are also using the fibres. Communicating products' sustainable footprint has become an ess