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Evaluation of cognitive subdomains, 25-hydroxyvitamin D, and 1,25-dihydroxyvitamin D in the European Male Ageing Study

Purpose: Although lower levels of vitamin D have been related to poor cognitive functioning and dementia in older adults, evidence from longitudinal investigations is inconsistent. The objective of this study was to determine whether 25-hydroxyvitamin D [25(OH)D] and 1,25-dihydroxyvitamin D [1,25(OH)2D] levels are associated with specified measures of cognitive decline in ageing men. Methods: The

C4BP(β-)-mediated immunomodulation attenuates inflammation in DSS-induced murine colitis and in myeloid cells from IBD patients

The most recent and promising therapeutic strategies for inflammatory bowel disease (IBD) have engaged biologics targeting single effector components involved in major steps of the immune-inflammatory processes, such as tumor necrosis factor, interleukins or integrins. Nevertheless, these molecules have not yet met expectations regarding efficacy and safety, resulting in a significant percentage o

The American Business Judgment Rule and Swedish Law - A Comparative Analysis of the American Business Judgment Rule and Its Eventual Counterpart in Swedish Law

Syftet med den här uppsatsen är att undersöka huruvida svenska styrelseledamöter och verkställande direktörer kan förvänta sig att de svenska domstolarna prövar affärsbeslut på ett liknande sätt som de amerikanska domstolarna prövar affärsbeslut. Undersökningen möjliggör en komparativrättslig analys av huruvida det finns något i svensk rätt som liknar den i amerikansk rätt existerande BJR, vilket The purpose of this thesis is to examine whether Swedish directors and CEOs can expect the Swedish courts to review business decisions in a similar way to how the American courts review business decisions. This examination enables a comparative analysis of whether something similar to the American business judgment rule exists in Swedish law, which some Swedish legal scholars claim. The American

CKD : A Call for an Age-Adapted Definition

Current criteria for the diagnosis of CKD in adults include persistent signs of kidney damage, such as increased urine albumin-to-creatinine ratio or a GFR below the threshold of 60 ml/min per 1.73 m2 This threshold has important caveats because it does not separate kidney disease from kidney aging, and therefore does not hold for all ages. In an extensive review of the literature, we found that G

Supplemental Association of Clonal Hematopoiesis With Incident Heart Failure

Background: Age-related clonal hematopoiesis of indeterminate potential (CHIP), defined as clonally expanded leukemogenic sequence variations (particularly in DNMT3A, TET2, ASXL1, and JAK2) in asymptomatic individuals, is associated with cardiovascular events, including recurrent heart failure (HF). Objectives: This study sought to evaluate whether CHIP is associated with incident HF. Methods: CHI

Genetically Predicted Levels of DNA Methylation Biomarkers and Breast Cancer Risk : Data From 228 951 Women of European Descent

BACKGROUND: DNA methylation plays a critical role in breast cancer development. Previous studies have identified DNA methylation marks in white blood cells as promising biomarkers for breast cancer. However, these studies were limited by low statistical power and potential biases. Using a new methodology, we investigated DNA methylation marks for their associations with breast cancer risk. METHODS

Recurrent Fusions Between YAP1 and KMT2A in Morphologically Distinct Neoplasms Within the Spectrum of Low-grade Fibromyxoid Sarcoma and Sclerosing Epithelioid Fibrosarcoma

Sclerosing epithelioid fibrosarcoma (SEF) is an aggressive soft tissue sarcoma. In the majority of cases, there is overexpression of MUC4, and most cases show EWSR1-CREB3L1 gene fusions. A subset of SEF displays composite histologic features of SEF and low-grade fibromyxoid sarcoma (LGFMS). These "hybrid" tumors are more likely to harbor the FUS-CREB3L2 fusion, which is also seen in most LGFMS. We

Prostate cancer early detection : Clinical practice guidelines in oncology™

Since the early 1990s, many variants of the tPSA assay have been introduced to increase the sensitivity of screening programs (cancer detection) while maintaining specificity (elimination of unnecessary biopsies). Again, these guidelines recommend ways that individuals and their physicians can use these new techniques rationally for early detection of prostate cancer. These guidelines are not desi

The GALAH survey : A new constraint on cosmological lithium and Galactic lithium evolution from warm dwarf stars

Lithium depletion and enrichment in the cosmos is not yet well understood. To help tighten constraints on stellar and Galactic evolution models, we present the largest high-resolution analysis of Li abundances A(Li) to date, with results for over $100\, 000$ GALAH (Galactic Archeology with HERMES) field stars spanning effective temperatures $5900\, \mathrm{K} \lesssim T_{\mathrm{eff}}\lesssim 7000

Household composition and the infant fecal microbiome : The INSPIRE study

Objectives: Establishment and development of the infant gastrointestinal microbiome (GIM) varies cross-culturally and is thought to be influenced by factors such as gestational age, birth mode, diet, and antibiotic exposure. However, there is little data as to how the composition of infants' households may play a role, particularly from a cross-cultural perspective. Here, we examined relationships

Validation of Risk Scoring Systems in Ursodeoxycholic Acid-Treated Patients With Primary Biliary Cholangitis

INTRODUCTION: Risk stratification based on biochemical variables is a useful tool for monitoring ursodeoxycholic acid (UDCA)-treated patients with primary biliary cholangitis (PBC). Several UDCA response criteria and scoring systems have been proposed for risk prediction in PBC, but these have not been validated in large external cohorts. METHODS: We performed a study on data of 1746 UDCA-treated

Ticagrelor versus Clopidogrel in Symptomatic Peripheral Artery Disease

BACKGROUND: Peripheral artery disease is considered to be a manifestation of systemic atherosclerosis with associated adverse cardiovascular and limb events. Data from previous trials have suggested that patients receiving clopidogrel monotherapy had a lower risk of cardiovascular events than those receiving aspirin. We wanted to compare clopidogrel with ticagrelor, a potent antiplatelet agent, in

Microsoft Word - DavidD, slutversion2008.doc

Microsoft Word - DavidD, slutversion2008.doc 57 David Petersson Förhållandet mellan anföringssats och anförd sats vid direkt anföring* Sammandrag. Vid direkt anföring uppvisar såväl anföringssats som anförd sats huvudsats- egenskaper och det är inte uppenbart hur förhållandet mellan satserna i en anförd mening ska förstås. I denna uppsats undersöks det hierarkiska förhållandet mellan anföringssats

https://projekt.ht.lu.se/fileadmin/_migrated/content_uploads/Fo__rha__llandet_.pdf - 2026-06-01

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1 SACO-S YRKANDEN MOT ARBETSGIVARVERKET 2025 Saco-S arbetar för att åstadkomma en långsiktigt hållbar verksamhet inom statlig sektor. Saco-S fackliga politik och arbetssätt präglas av en vilja att bidra till den statliga verksamhetens resultat och utveckling. Vi eftersträvar avtal som förändras utifrån ändrade förutsättningar och behov och avtal som stödjer ett föränderligt arbetsliv. För att möta

https://www.saco.se/globalassets/lokala-akademikerforeningar/statlig/saco-s/dokument/avtal/2025/saco-s-yrkanden-2025.pdf - 2026-06-01

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a k t u el lt o m v e t ensk a p o ch hä l sa • j u n i 2010 Solen, sjukdom och hälsa Juni 2011 Denna tidskrift ges ut av Lunds universitet och Region Skåne Aktuellt om Vetenskap & hälsa a k t u el lt o m v e t ensk a p o ch hä l sa • j u n i 2010 Aktuellt om Vetenskap&hälsa God läsning! Solen är som vi alla vet en förutsättning för livet på jor- den. Utan sol ingen varm jord och atmosfär, ingen f

https://www.vetenskaphalsa.se/wp-content/uploads/2011/05/Aktuellt_om_vet_o_halsa_juni_11.pdf - 2026-06-01

Certified reference material for radionuclides in fish flesh sample IAEA-414 (mixed fish from the Irish Sea and North Sea)

A certified reference material (CRM) for radionuclides in fish sample IAEA-414 (mixed fish from the Irish Sea and North Seas) is described and the results of the certification process are presented. Nine radionuclides (K-40, Cs-137, Th-232, U-234, U-235, U-238, Pu-238, Pu239+240 and Am-241) were certified for this material. Information on massic activities with 95% confidence intervals is given fo

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S¿RTRYCK UR VAREN DSBYGDER NORRA ALLBO H EMBYG DSFO RE N I N G t9 53 fa eT )t*ü ,r*Å N,àr*,^ au't n aJ A'/. 6 f 7 ¿ ALVESTÀ 1953 Ero¡ Lrxnsr¡öus SöN¡n, Bonrrvcxrr¡ CARL \ØILHELM VoN SYDO\Ø 1878 - 1952 Av O. LrNosrrN Meddelandet om professor C. \ø. v. Sydows bortgång den 14 mars 1952 mottogs i vida kretsar med känslor av djup saknad och varmt deltagande. Hans vetenskapliga gärning är känd och erkän

https://www.folklivsarkivet.lu.se/fileadmin/user_upload/folklivsarkivet/images/artiklar_i_pdf-format/Lindsten_O__Carl_Wilhelm_von_Sydow__Saertryck_ur_Vaerendsbygder.pdf - 2026-06-01

Fracture energy in birch

Fracture energy in birch Master’s Dissertation Structural Mechanics EMMA ESBJÖRNSSON and JOHAN SVENSSON EXPERIMENTAL TESTING OF BIRCH WOOD Fracture energy and its applicability in dowel-type joints DEPARTMENT OF CONSTRUCTION SCIENCES DIVISION OF STRUCTURAL MECHANICS ISRN LUTVDG/TVSM--24/5275--SE (1-78) | ISSN 0281-6679 MASTER’S DISSERTATION Supervisor: HENRIK DANIELSSON, Associate Professor, Divis

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm5000/web5275.pdf - 2026-06-01