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INTRODUCTION: The immune microenvironment plays a crucial role in the progression of colorectal cancer (CRC), but its variation across primary tumors and metastatic sites remains incompletely understood. In this study, we compared the composition and prognostic significance of the immune microenvironment in lung metastases, paired primary tumors, and liver metastases from a retrospective cohort of

BACKGROUND: Post COVID-19 condition remains a complex and challenging issue, with diverse manifestations, despite accumulating research and clinical experience. Dyspnea is one of the most common symptoms reported in post COVID-19 condition. Cardiopulmonary exercise testing (CPET) offers a cohesive assessment of dyspnea and exercise limitations. The Nijmegen questionnaire is a form for assessment o

The use of prosthetic hands is limited in part by the lack of sensory feedback to the wearer. In order to provide sensory feedback, an adequate number of sensors must be integrated with the prosthesis. The WiseSkin project targets the use of artificial skin embedding ultra-low power wireless sensor nodes. This presentation provides an overview of the WiseSkin project and the current status of the

Constructing simulation models can be a complex and time-consuming task, in particular if the models are constructed from scratch or if a general-purpose simulation modeling tool is used. In this paper, we propose a model construction framework, which aims to simplify the process of constructing discrete event simulation models for emergency medical service (EMS) policy analysis. The main building

INTRODUCTION: Programmed death-ligand 1 (PD-L1) expression is used for treatment prediction in non-small cell lung cancer (NSCLC). While cytology may be the only available material in the routine clinical setting, testing in clinical trials has mainly been based on biopsies.METHODS: We included 2 retrospective cohorts of paired, concurrently sampled, cytological specimens and biopsies. Also, the l

Shareholder Litigation in Response to the Climate Emergency and Human Right to a Healthy Environment in Asia and the Pacific Report prepared for the Raoul Wallenberg Institute of Human Rights and Humanitarian Law by Asst Prof Althaf Marsoof, Assoc Prof Anil K Samtani, and Asst Prof Alan K Koh Division of Business Law, College of Business, Nanyang Technological University, Singapore 6 June 2023 Rep

https://rwi.lu.se/wp-content/uploads/2024/06/Shareholder-Litigation-in-Response-to-the-Climate-Emergency.pdf - 2026-05-28

Saco-rådet Umeå kommun KALLELSE 2018-03-xx Saco-rådsrepresentanter/ Saco-medlemmar KALLELSE TILL SACO-RÅDETS ÅRSMÖTE Tid Tisdag 2018-03-27 kl. 17.00 Plats Saco-rådets lokaler, Renmarkstorget 8, 3tr Program Årsmöte. Anmälan Senast 2018-03-20 till Lena Svedjehed, lena.svedjehed@umea.se Saco-rådets uppgifter är bl.a. att handlägga de frågor som enskilt förbund delegerar och att vara förbundens kontak

https://www.saco.se/globalassets/lokala-akademikerforeningar/kommun-och-region/umea-kommun/dokument/arsmoteshandlingar-2018-saco.docx - 2026-05-29

Microsoft Word - FU_vid_CEE_beslut.docx Address P O Box 124, SE 221 00 Lund, Sweden Street address: John Ericssons väg 3 Telephone , +46 (0)46-222 3626 Email per.warfvinge@rektor.lth.se Web http://www.lth.se Per Warfv inge, Professor Cent re for Engineer ing Educat ion Ramverk för Forskarutbildning i ämnet Pedagogisk utveckling inom teknikvetenskap (TEIDEF05) vid Centre for Engineering Education (

https://www.lth.se/fileadmin/cee/Documents/FU_vid_CEE_beslut.pdf - 2026-05-28

Nuclear quadrupole resonance (NQR) offers an unequivocal method of detecting and identifying land mines. Unfortunately, the practical use of NQR is restricted by the low signal to noise ratio (SNR), and means to improve the SNR are vital to enable a rapid, reliable and convenient system. In this paper, we develop a non-linear least squares detector exploiting the temperature dependency of the NQR

Abstract in Undetermined Samtalsanalytisk studie som ger metodisk kunskap om jourläkares medicinska frågeprocedurer i samtal med diabetiker efter insulinkoma samt hur ambulanssjuksköterskor och jourläkare sambedömer och kommer fram till ett medicinskt beslut i relation till ambulansriktlinjer.

Background: Less than 500 participants have been included in randomized trials comparing hypothermia with regular care for out-of-hospital cardiac arrest patients, and many of these trials were small and at a high risk of bias. Consequently, the accrued data on this potentially beneficial intervention resembles that of a drug following small phase II trials. A large confirmatory trial is therefore

Introduction: Neoadjuvant chemotherapy (NAC) is an established treatment option for early breast cancer, potentially downstaging the tumor and increasing the eligibility for breast-conserving surgery (BCS). The primary aim of this study was to assess the rate of BCS after NAC, and the secondary aim was to identify predictors of application of BCS after NAC. Materials and methods: This was an obser

Development of the Drosophila visceral muscle depends on Anaplastic Lymphoma Kinase (Alk) receptor tyrosine kinase (RTK) signaling, which specifies founder cells (FCs) in the circular visceral mesoderm (VM). Although Alk activation by its ligand Jelly Belly (Jeb) is well characterized, few target molecules have been identified. Here, we used targeted DamID (TaDa) to identify Alk targets in embryos

Breastfeeding profoundly shapes the infant gut microbiota, which is critical for early life immune development, and the gut microbiota can impact host physiology in various ways, such as through the production of metabolites. However, few breastmilk-dependent microbial metabolites mediating host–microbiota interactions are currently known. Here, we demonstrate that breastmilk-promoted Bifidobacter

This paper presents four different tangible interactive prototypes designed to support the continuation of balance rehabilitation at home. The interactive prototypes are designed to provide a more enjoyable and experience when performing balance rehabilitation exercises. Early results from preliminary tests with stroke survivors and rehabilitation professionals are promising. The aim of the design

As the COVID-19 pandemic continues to affect societies across the world, the ongoing economic and social disruptions are likely to present fundamental challenges for current and future biodiversity conservation. We review the literature for outcomes of past major societal, political, economic and zoonotic perturbations on biodiversity conservation, and demonstrate the complex implications of pertu

We investigate kinetic broadening effects on the length distributions of gold-catalyzed InAs nanowires having different diameters. It is shown that the length distributions acquire bimodal shape when the longest nanowires exceed the diffusion length of indium adatoms on the nanowire sidewalls. Later on, the length distributions recover unimodal shapes. We develop a theoretical model that is capabl

Kan en enskild lag underlätta planläggningsarbetet ute i kommunerna? Hur arbetar din kommun för att bygga och bevara befintliga hyresrätter? I dagsläget uppfinner varje kommun hjulet själva, men det kan snart vara över. Ett nytt lagförslag är på ingång! Lagstiftaren vill att PBL och byggnadsbranschen blir mer förutsägbar, effektiv och smidig. Bostadskrisen har länge varit på tapeten och röster hörThe Swedish housing market faces a number of concerns. There are too few rental units with cheap rent available and the capital input to buy your own freehold title or tenant-ownership is skyrocketing. The threshold for entering the housing market is getting higher and groups such as young adults, new arrivals, disabled people, and the elderly are the ones who are the most exposed. Developers get