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Analysis of somatic mutation activity in multiple V kappa genes involved in the response to 2-phenyl-5-oxazolone

We have studied somatic mutation activity early in a response to 2-phenyl-5-oxazolone coupled to ovalbumin (phOx-OVA). Although the V kappa Ox1 gene rearranged to J kappa 5 is known to predominate in this response, other closely related V kappa genes are involved. We compared the introduction of point mutations into V kappa Ox1 genes and into a set of related V kappa genes rearranged to the same J

Allergome-wide peptide microarrays enable epitope deconvolution in allergen-specific immunotherapy

Background: The interaction of allergens and allergen-specific IgE initiates the allergic cascade after crosslinking of receptors on effector cells. Antibodies of other isotypes may modulate such a reaction. Receptor crosslinking requires binding of antibodies to multiple epitopes on the allergen. Limited information is available on the complexity of the epitope structure of most allergens. Object

FGFR1 overexpression in non-small cell lung cancer is mediated by genetic and epigenetic mechanisms and is a determinant of FGFR1 inhibitor response

Amplification of fibroblast growth factor receptor 1 (FGFR1) in non-small cell lung cancer (NSCLC) has been considered as an actionable drug target. However, pan-FGFR tyrosine kinase inhibitors did not demonstrate convincing clinical efficacy in FGFR1-amplified NSCLC patients. This study aimed to characterise the molecular context of FGFR1 expression and to define biomarkers predictive of FGFR1 in

Tartrate resistant acid phosphatase 5 (TRAP5) mediates immune cell recruitment in a murine model of pulmonary bacterial infection

Introduction: During airway infection, upregulation of proinflammatory cytokines and subsequent immune cell recruitment is essential to mitigate bacterial infection. Conversely, during prolonged and non-resolving airway inflammation, neutrophils contribute to tissue damage and remodeling. This occurs during diseases including cystic fibrosis (CF) and COPD where bacterial pathogens, not least Pseud

Spatial immunophenotyping of the tumour microenvironment in non-small cell lung cancer

INTRODUCTION: Immune cells in the tumour microenvironment are associated with prognosis and response to therapy. We aimed to comprehensively characterise the spatial immune phenotypes in the mutational and clinicopathological background of non-small cell lung cancer (NSCLC).METHODS: We established a multiplexed fluorescence imaging pipeline to spatially quantify 13 immune cell subsets in 359 NSCLC

PD‐L1 Expression in Non‐Small Cell Lung Cancer Specimens : Association with Clinicopathological Factors and Molecular Alterations

Immune checkpoint inhibitors (ICI) targeting programmed cell death‐1 or its ligand (PD‐ L1) have improved outcomes in non‐small cell lung cancer (NSCLC). High tumor PD‐L1 expression, detected by immunohistochemistry (IHC) typically on formalin‐fixed paraffin‐embedded (FFPE) histological specimens, is linked to better response. Following our previous investigation on PD‐L1 in cytological samples, t

Estimating surface flow over digital elevation models using a new improved form-based algorithm

This paper discusses new improvements of a form-based algorithm, which is used to estimate flow distribution over a continuous surface. In the new form- based algorithm (IFBFD), cells in a DEM are classified into five different classes. The classes are Peaks, Complicated, Sinks, Flats and Undisturbed cells. The method of how to estimate the flow distribution from each cell depends on its class. Es

Phobos base : Concept of operations and architecture for a permanent human presence on the Martian moon Phobos

This paper is based on the work done for the 2017 AIAA Student Design Competition-Human Spaceflight: Phobos Base. One of humanity's major challenges when travelling to Mars is represented by the existence of an atmosphere around the red planet. In fact, even though the Martian atmospheric density is only about 1% of that of Earth, the entry, descent and landing (EDL) procedure for large payloads i

Interdisciplinary pedagogy in

Interdisciplinary pedagogy in Interdisciplinary pedagogy in higher education Proceedings from Lund University’s Teaching and Learning Conference 2019 EDITORS: JOHANNA BERGQVIST RYDÉN, ANNE JERNECK, JESSIKA LUTH RICHTER & KARIN STEEN LUND UNIVERSITY 1 Interdisciplinary pedagogy in higher education Proceedings from Lund University's Teaching and Learning Conference 2019 Editors: Johanna Bergqvist Ry

https://www.ahu.lu.se/fileadmin/user_upload/ahu/PDF/Proceedings_Interdisciplinary_pedagogy_in_higher_education_Lund_University_2019.pdf - 2026-05-25

Civilingenjör i elektroteknik

Civilingenjör i elektroteknik | LTH, Lunds Tekniska Högskola Hoppa till huvudinnehåll Vi använder cookies och andra spårningsteknologier för att förbättra användarupplevelsen på vår webbplats, för att visa dig personligt innehåll och riktade annonser och för att analysera vår webbplatstrafik. Läs mer om cookies. Absolut nödvändiga cookies Dessa cookies är nödvändiga för att webbplatsen ska fungera

https://www.lth.se/utbildning/elektroteknik/ - 2026-05-25

Module 1: What is Global China? - The Raoul Wallenberg Institute of Human Rights and Humanitarian La

Module 1: What is Global China? - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation of Programm

https://rwi.lu.se/module-1-what-is-global-china/ - 2026-05-26

Module 2: China’s environmental journey - The Raoul Wallenberg Institute of Human Rights and Humanit

Module 2: China’s environmental journey - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation of

https://rwi.lu.se/module-2-chinas-environmental-journey/ - 2026-05-26

Caterina Doglioni

Affiliated Contact details Email: caterina [dot] doglioni [at] fysik [dot] lu [dot] seOrganisation Particle and nuclear physics Service point: 14 WebpageCaterina Doglionis profile in Lund University research portalOther affiliations Project manager Particle and nuclear physics Senior lecturer Particle and nuclear physics Member of Strategic Research Area eSSENCE: The e-Science Collaboration Public

https://www.particle-nuclear.lu.se/caterina-doglioni - 2026-05-27

No title

FORSKARE: Maria Rosvall1,3, Martin Lindström1,3, Farhad Ali Khan1,3, Ellinor Bengtsson2 , Margareta Dahlén Nord2, Anna Friberg2, Mathias Grahn1, Birgit Modén1,3, Kontie Moussa1,3, Per-Olof Östergren1,3 Juan Merlo1,3 KLINIK/INSTITUTION: 1Socialmedicinska enheten, Universitets- sjukhuset MAS, 2Centrum för folkhälsa och miljö i Region Skåne, 3Inst. för kliniska vetenskaper – Malmö, Lunds universitet

https://www.vetenskaphalsa.se/wp-content/uploads/2010/01/09.MariaRosvall_hur-m%C3%A5r-sk%C3%A5ne1.pdf - 2026-05-26

The "Black Butterflies": Color in God Help the Child and the Inverted White Gaze

The discourse on beauty has primarily been focused on the white gaze to prescribe its normative standards. The white gaze conceptualizes the way in which beauty is dwelled on within society: the foisting of Caucasian-looking beauty canons on black women, and the veneration of whiteness as superior. Black bodies are vanguards, either being desired or erased. In literature, the expression “white gaz

En husmoder ska vara tusenkonstnär : en kunskapshistorisk undersökning av hemmets rationalisering 1946–1956

A housewife of many trades: applying history of knowledge to the rationalization of the home in 1946–1956. After World War II, Swedish women were expected to return to their work at home, due to a shortfall of work for men. However, to make housework more attractive for women, its status needed to increase. One way to make housework more appealing for women was to rationalize the home and therefo

Den från mervärdesskatt undantagna värdepappershandeln: en jämförelse av tolkning och tillämpning av undantagsregeln i EU-rätt och svensk rätt

Värdepappershandel tillsammans med annan finansiell verksamhet har undantagits från mervärdesskatteplikt inom EU sedan 1977, när Direktivet 77/388/EEC lagstiftades. Ursprungligen stadgades undantaget för dessa finansiella tjänster på grund av skattetekniska problem som uppkommer vid framställande av det beskattningsbara underlaget. Direktivet, som sedermera har ersatts av Direktivet 2006/112/EC (tTrade in securities along with other financial activities has been enjoying the VAT exempt status within the EU since 1977, when Directive 77/388/EEC was passed. The VAT exemption for the financial services was originally enacted due to the difficulties relating to defining the taxable amount for the VAT purposes. The mentioned Directive, which has consequently been replaced by Directive 2006/112/

Study on EEG-based carelessness warnings to bus driver

To reduce traffic accidents caused by driver factors, realizing technology to monitor and preemptively respond to the state of a driver is necessary. In this study, drivers' electroencephalogram (EEG) data during driving were acquired, and the effect of carelessness warnings was analyzed. The frequency of carelessness per minute was low for the case of presence of warnings. The originality of this