Sökresultat

This dissertation investigates the relation between aesthetics and politics by interpreting three experimental novels by Virginia Woolf, Djuna Barnes and Gertrude Stein. By theorizing the relation between language, subject, voice and ideology it questions the autonomous subject as a ground for political action and criticality. This is done by challenging language as a vehicle for individual expres

Models of the engineering design process and of the development process nowadays present similar forms in the engineering design literature and interact in a similar way. These models are often presented as generic, in order to be used in a wide area of applications. This interaction is however not unproblematic, and in this publication we present some important issues and challenge the generic as

Epithelial ovarian carcinoma has in general a poor prognosis since the vast majority of tumors are genomically unstable and clinically highly aggressive. This results in rapid progression of malignancy potential while still asymptomatic and thus in late diagnosis. It is therefore of critical importance to develop methods to diagnose epithelial ovarian carcinoma at its earliest developmental stage,

Optimal linearly constrained minimum variance (LCMV) filtering methods have recently been applied to fundamental frequency estimation. Like many other fundamental frequency estimators, these methods are constructed using an estimate of the inverse data covariance matrix. The required matrix inverse is typically formed using the sample covariance matrix via data partitioning, although this is well-

The current study investigated if and how students' behaviour when using a teachable agent-based educational software were related to their working memory capacity. Thirty Swedish students aged 11-12, participated in the study. Results showed that differences in behaviour such as time spent on an off-task activity, time spent on interactive dialogues, and the number of tests that students let thei

A high energy supply and appropriate amount of polyunsaturated fatty acids is crucial for proper growth and development in neonates. The capacity for fatty acid absorption in newborns is however hampered due to an undeveloped pancreatic function combined with a low bile output. This seems in particular to limit fatty acid absorption in babies given infant formulas. Since interaction between the li

Solitary fibrous tumor (SFT) is a mesenchymal neoplasm displaying variable morphologic and clinical features. To identify pathogenetically important genetic rearrangements, 44 SFTs were analyzed using a variety of techniques. Chromosome banding and fluorescence in situ hybridization (FISH) showed recurrent breakpoints in 12q13, clustering near the NAB2 and STAT6 genes, and single nucleotide polymo

The purpose of this work was to evaluate three motion-monitoring systems: Sentinel (TM), Catalyst (TM) (both C-RAD) and Real-time Position Management (RPM (TM)) system (Varian Medical Systems Inc) for respiratory gating in radiotherapy. To measure the systems. latency, an in-house built circuit with a microcontroller operating a piston was used. The trigger pulse was sent from the gating systems t

Whilst innate B1-B cells are atheroprotective, adaptive B2-B cells are considered pro-atherogenic. Different subsets of B regulatory cells (B-reg) have been described. In experimental arthritis and lupus-like disease, B-reg are contained within the CD21(hi)CD23(hi)CD24(hi) B cell pool The existence and role of B-reg in vascular disease is not known. We sought to investigate the existence, identity

A 37-year-old female subject had been convicted of driving under the influence of alcohol, and 19 months later, claimed abstinence after supervised disulfiram treatment. Our aim was to elucidate the value of direct ethanol metabolites as measures of abstinence. Ethyl glucuronide (EtG) and fatty acid ethyl esters (FAEE) in hair, phosphatidylethanol in whole blood and EtG and ethyl sulphate in urine

We proposed a 4×8 array antenna with aperture-coupled patch antenna elements. The antenna was designed for 60 GHz operation and fabrication on the low-temperature cofired ceramic(LTCC) substrate(εr=5.8). The feedline with the stub was designed to enhance the radiating element bandwidth and the transition characteristics between the waveguide (WG) and microstrip line(MSL). Through the optimization

Cylindromatosis gene (CYLD) is a ubiquitously expressed deubiquitinating enzyme, which interacts with members of the NF-kappa B signaling pathway and attenuates NF-kappa B and JNK signaling. Here, we report that DC derived from transgenic mice, which solely express a naturally occurring CYLD isoform (CYLDex7/8), display a higher content of nuclear RelB and express elevated levels of NF-kappa B fam

Gene amplification is a common phenomenon in malignant neoplasms of all types. One mechanism behind increased gene copy number is the formation of ring chromosomes. Such structures are mitotically unstable and during tumor progression they accumulate material from many different parts of the genome. Hence, their content varies considerably between and within tumors. Partly due to this extensive va

Many men with elevated prostate-specific antigen (PSA) levels in serum do not have aggressive prostate cancer and undergo unnecessary biopsy. Retrospective studies using cryopreserved serum suggest that four kallikrein markers can predict biopsy outcome.

Objectives The aim of the study was to examine the predictive value of QRS duration and morphology during watchful waiting in asymptomatic patients with aortic stenosis (AS). Background QRS duration and morphology are associated with poor prognosis in many different populations, but the predictive value, particularly of the risk of sudden cardiac death (SCD), in asymptomatic patients with AS has n

The Tibetan highlands host the largest alpine grassland ecosystems worldwide, bearing soils that store substantial stocks of carbon (C) that are very sensitive to land use changes. This study focuses on the cycling of photoassimilated C within a Kobresia pygmaea pasture, the dominating ecosystems on the Tibetan highlands. We investigated short-term effects of grazing cessation and the role of the

Our knowledge of the binding sites for neutralizing Abs (NAb) that recognize a broad range of HIV-1 strains (bNAb) has substantially increased in recent years. However, gaps remain in our understanding of how to focus B cell responses to vulnerable conserved sites within the HIV-1 envelope glycoprotein (Env). In this article, we report an immunization strategy composed of a trivalent HIV-1 (clade