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Water Accommodation on Ice and Organic Surfaces: Insights from Environmental Molecular Beam Experiments

Water uptake on aerosol and cloud particles in the atmosphere modifies their chemistry and microphysics with important implications for climate on Earth. Here, we apply an environmental molecular beam (EMB) method to characterize water accommodation on ice and organic surfaces. The adsorption of surface-active compounds including short-chain alcohols, nitric acid, and acetic acid significantly aff

Sample Size in Clinical Cardioprotection Trials Using Myocardial Salvage Index, Infarct Size, or Biochemical Markers as Endpoint.

Cardiac magnetic resonance (CMR) can quantify myocardial infarct (MI) size and myocardium at risk (MaR), enabling assessment of myocardial salvage index (MSI). We assessed how MSI impacts the number of patients needed to reach statistical power in relation to MI size alone and levels of biochemical markers in clinical cardioprotection trials and how scan day affect sample size.

Beyond Mean-Field Description of Bose-Einstein Condensate

This thesis work is on the theoretical description of dilute Bose-Einstein condensates (BEC) that are non-uniform, meaning that more than one single-particle state is occupied. This phenomenon is usually called quantum depletion. A common model for the ground state of a dilute and weakly interacting BEC is the mean-field (MF) approximation leading to the Gross-Pitaevskii (GP) equation. However, fo

Generalstrejk, sabotage och terror: anarkosyndikalisternas strategi före första världskriget i D. Novomirskijs och A. Jensens skrifter

This essay investigates the revolutionary strategy of the anarcho-syndicalists in Russia and Sweden before the World War I. The purpose of the research is to gain new knowledge about the relationship between the goal and the method from the point of view of the ideology of anarchosyndicalism. The study explores how the same ideology shaped strategy in two different national contexts. Publications

Back to Basics: How Trump’s Zero Tolerance Policy evidenced the Inefficiency of the Human Rights Framework, and the Urgency to re-center Human Dignity

In 2018, images of migrant children held in cages and sleeping on concrete floors while being held in immigration detention in the United States shocked the world. Within the framework of the zero tolerance policy on immigration mandated by President Trump, thousands of families have been separated at the border. The trauma borne out of these separations was purposefully capitalized upon to serve

The Impact of Country-Specific Contextual Factors on the Outcome of Section 1502 of the Dodd-Frank Act Regulating Conflict Minerals in the Democratic Republic of Congo

The conflict mineral crisis has been ongoing in the DRC for nearly two decades, with armed groups and increased military presence have played on the tin, tantalum, tungsten and gold to fund a brutal war across the eastern region of the country. Recent international efforts to tackle such illicit trade in conflict minerals has focused on requiring relevant stakeholders involved in the mineral sourc

Low Plasma Level of Atrial Natriuretic Peptide Predicts Development of Diabetes: The Prospective Malmo Diet and Cancer Study.

Context:The cardiac natriuretic peptides are involved in blood pressure regulation, and large cross-sectional studies have shown lower plasma levels of N-terminal pro-natriuretic peptide levels [N-terminal atrial natriuretic peptide (N-ANP) and N-terminal brain natriuretic peptide (N-BNP)] in patients with insulin resistance, obesity, and diabetes.Objective:In this study, we prospectively tested w

Core-shell nanowires: From the ensemble to single-wire characterization

Recent investigations of core-shell nanowires using synchrotron radiation techniques deduced the average structural parameters of heterostructure core-shell nanowires. Here, we report on first results and discuss the problems arising when measuring such complex nanostructures by using nanofocusing X-ray techniques. InAs/IAsP core-shell nanowires exhibit a certain bending, the origin of which is de

Modernitet och myt : avförtrollning och återförtrollning i Knut Hamsuns Sult, Mysterier och Pan

Knut Hamsun (1859-1952) is generally regarded as one of the first proponents of modern literature in Scandinavia. The present thesis discusses the author’s breakthrough phase which took place around the year 1890. This was an era when societal modernity became established in the Scandinavian countries, and new and revolutionary ideas and norms appeared concerning society, science, and art. Hamsun

Immunoassay for the discrimination of free prostate-specific antigen (fPSA) forms with internal cleavages at Lys(145) or Lys(146) from fPSA without internal cleavages at Lys(145) or Lys(146)

Total levels of circulating prostate-specific antigen (tPSA) are strongly associated with prostate cancer (PCa) risk and outcome but benign prostate disease is the most frequent cause of a moderately elevated PSA level. Free PSA (fPSA) forms are independently associated with PCa risk and contribute modest diagnostic enhancements above and beyond tPSA alone. We developed an immunoassay for fPSA sub

A high-throughput pathology approach for further insight into the role of RBM3 as a biomarker of prognosis and chemotherapy response in human cancer

Popular Abstract in Swedish Allt fler människor drabbas av cancer, som idag är den ledande dödsorsaken globalt. De vanligaste cancerformerna i världen är lungcancer, bröstcancer och tjocktarmscancer och det är störst risk att dö i lungcancer, levercancer och magcancer. Även i Sverige ökar antalet cancerfall, till stor del på grund av att vi lever allt längre och cancer är idag en av våra stora folCancer incidence is increasing and it is the number one cause of death worldwide. Cancer is a highly heterogeneous disease and there is a great need for new early diagnostic, prognostic and treatment predictive biomarkers in order to improve patient outcomes. The RNA-binding motif protein 3, RBM3, is an emerging candidate biomarker of favourable prognosis and treatment response in several types of

Characterisation of Arteriovenous Fistula’s sound recordings using principal component analysis

In this study, a signal analysis framework based on the Karhunen-Loève expansion and k-means clustering algorithm is proposed for the characterisation of arteriovenous (AV) fistula’s sound recordings. The Karhunen-Loève (KL) coefficients corresponding to the directions of maximum variance were used as classification features, which were clustered applying k-means algorithm. The results showed that

Intradermal Delivery of TLR Agonists in a Human Explant Skin Model: Preferential Activation of Migratory Dendritic Cells by Polyribosinic-Polyribocytidylic Acid and Peptidoglycans

TLR agonists are attractive candidate adjuvants for therapeutic cancer vaccines as they can induce a balanced humoral and T cell-mediated immune response. With a dense network of dendritic cells (DCs) and draining lymphatics, the skin provides an ideal portal for vaccine delivery. Beside direct DC activation, TLR agonists may also induce DC activation through triggering the release of inflammatory

Objective monitoring of nasal airway inflammation in rhinitis

Allergic rhinitis is an inflammatory nasal disorder in which a range of different cells participates. A variety of approaches has been used to monitor nasal inflammation objectively to investigate disease processes and to evaluate the effect of therapeutic intervention. These approaches include nasal lavage, nasal cytology, and nasal biopsy, together with the more recently established measurement

Recasting the Dublin Regulation : an analysis of the impact of the M.S.S. and N.S./M.E. judgments on the recast of the Dublin Regulation

Syftet med Dublinförordningen är att se till att asylansökningar behandlas av endast en medlemsstat, för att undvika fenomenen “asylsum shopping” och “refugees in orbit”. Förordningen består av en hierarki av kriterier för att fastställa vilken stat som är ansvarig, men detta har också lett till principen om ömsesidigt förtroende mellan medlemsstaterna, där alla stater förutsätts ha samma nivå av The purpose of the Dublin Regulation is to ensure that applications for asylum will be considered by one Member State, avoiding the phenomena of “asylum shopping” and “refugees in orbit”. The Regulation consists of a hierarchy of criteria for determining the responsible state, however, this has also resulted in the principle of Mutual Trust between Member States, where all states are presumed to h

Ekonomiskt våld – okänt, outtalat, oviktigt? – Synen på ekonomiskt våld i samband med straffrättslig reglering av stöld, skadegörelse och grov kvinnofridskränkning

Termen ”ekonomiskt våld” är för många ett relativt okänt begrepp, vilket bara under de senaste åren har börjat leta sig in i media och den allmänna samhällsdebatten. Bland forskare betraktas det ekonomiska våldet som mycket allvarligt och framför allt som en stor riskfaktor för att våldsutsatta kvinnor ska stanna i en våldsam relation. I svensk rätt finns inget straffbud som uttryckligen tar siktThe term “economic violence” is a concept that is relatively unfamiliar to many, which only in recent years has begun to find its way into the media and the general social debate. Many researchers regard economic violence as a very serious issue and, above all, as a major risk that may cause women that are victims of domestic violence to stay in a violent relationship. In Swedish law, there are n

Aggregation potency and proinflammatory effects of SARS-CoV-2 proteins

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, is primarily known as a respiratory disease. The continued study of the disease has shown that long-term COVID-19 symptoms include persisting effects of the virus on the brain when the infection is over, possibly even leading to neurodegeneration. However, the exact mechanisms of

Sex-Specific Cardiovascular Consequences of Long-Term High-Salt Diet in Mice

BACKGROUND: Excessive dietary salt intake is associated with elevated blood pressure and damage to organs including the heart, vasculature, and kidneys. Women are more prone to salt-sensitive hypertension, yet preclinical studies often focus on men.METHODS: To examine sex-specific responses to chronic salt loading, male and female C57Bl6/J mice were fed a high-salt diet (HSD; 8% NaCl) from 7 to 14