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Recent studies demonstrate that Black Carbon (BC) pollution in economically developing megacities remain higher than the values, which the World Health Organization considers to be safe. Despite the scientific evidence of the degrees of BC exposure, there is still a lack of understanding on how the severe levels of BC pollution affect human health in these regions. We consider information on the r

Atopic dermatitis (AD) is a clinically defined, highly pruritic, chronic inflammatory skin disease of children and adults. The diagnosis is made using evaluated clinical criteria. Disease activity is best measured with a composite score assessing both objective signs and subjective symptoms, such as SCORAD. The management of AD must consider the clinical and pathogenic variabilities of the disease

A series of turbulent premixed methane/air jet flames are studied using simultaneous planar lase diagnostic imaging of OH/CH/temperature and CH/OH/CH2O. The Karlovitz number of the flames ranges from 25 to 1500, and the turbulence intensity ranges from 16 to 200. These flames can be classified as highly turbulent flames in the thin reactions zone (TRZ) regime and distributed reaction zone (DRZ) re

Abstract in UndeterminedIn this paper we describe and reflect upon a novel methodology using attention cards to facilitate communication, concentration and creativity in a user requirement workshop with seniors. Previous research indicates that seniors tend to lose focus and start cross talking during workshops, which results in broad and shallow findings. However, our findings indicate that the u

Identifying optimal inspection and repair strategies for offshore jacket structures is a challenging task. We present an approach, which is based on recent developments in the field of risk-based operation and maintenance planning at the structural system level. The approach utilizes heuristics to define inspection and repair strategies at the system level and to reduce the search space of possibl

Over the last decade, Unmanned Aerial Vehicles (UAVs) have been used for monitoring construction and operation of civil infrastructure, as well as industrial facilities and power plants. Their operational simplicity along with time-and-cost-related benefits have already rendered them attractive for structural surveying. Nevertheless, the field of UAV research currently lacks a targeted employment

A software prototype is developed for assessing and updating the reliability of single-cell prestressed concrete box girders subjected to chloride-induced reinforcement corrosion. The underlying system model consists of two integrated sub-models: a condition model for predicting the deterioration state of the box girder and a structural model for evaluating the overall system reliability. The cond

The ERBB2 gene encodes a receptor tyrosine kinase also known as HER2. The gene is amplified and overexpressed in one-fifth of breast carcinomas; patients with such tumors benefit from targeted treatment with trastuzumab or other drugs blocking the receptor. In addition, ERBB2 has been shown to be amplified and/or overexpressed in a variety of other malignancies. Notably, both alveolar and embryona

Autonomic computing systems adapt themselves thousands of times a second, to accomplish their goal despite changing environmental conditions and demands. The literature reports many decision mechanisms, but in most realizations a single one is applied. This paper compares some state-of-the-art decision making approaches, applied to a self-optimizing autonomic system that allocates resources to a s

Spleen cells from WF rats immunized to allogeneic lymphoid cells or to syngeneic colon carcinomas and from unimmunized controls were separated by countercurrent distribution in aqueous two-phase systems. The cells were assayed for cytotoxicity to allogeneic fibroblasts or syngeneic colon carcinoma cells and to syngeneic fibroblasts in a 24-hr 51Cr-release assay. Cells from immunized rats which sel

Mesenchymal stromal cell (MSC)-based therapies for inflammatory diseases rely mainly on the paracrine ability to modulate the activity of macrophages. Despite recent advances, there is scarce information regarding changes of the secretome content attributed to physiomimetic cultures and, especially, how secretome content influence on macrophage activity for therapy. hLMSCs from human donors were c

Beside its classical role as a serum effector system of innate immunity, evidence is accumulating that complement has an intracellular repertoire of components that provides not only immune defense, but also functions to maintain cellular homeostasis. While complement proteins, mainly the central component C3, have been detected in B cells, their exact function and source remain largely unexplored

Stellar ages are a crucial component to studying the evolution of the Milky Way. Using Gaia DR2 distance estimates, it is now possible to estimate stellar ages for a larger volume of evolved stars through isochrone matching. This work presents [M/H]-age and [α/M]-age relations derived for different spatial locations in the Milky Way disc. These relations are derived by hierarchically modelling the

A sensitive and rapid enzyme-linked immunosorbent assay for simultaneous quantitation of free and IgA-complexed human protein HC was developed with monoclonal murine antibodies. The total amount of protein HC (free plus IgA-complexed) was measured by a competitive procedure while the protein HC-IgA complex was quantitated by a sandwich enzyme immunoassay. The amount of free protein HC was then obt

When selecting for monoclonal antibodies of a desired affinity, affinity chromatography can be a feasible alternative. This is of particular interest when low affinity monoclonal antibodies (dissociation constant (Kd) > 10(-4) M) are screened, as they are not easily recognised by traditional immunoassay procedures. In this study we have evaluated this approach by monitoring low affinity monoclonal

ObjectivePediatric anxiety disorders can have a chronic course and are considered gateway disorders to adult psychopathology, but no consistent predictors of long-term outcome have been identified. A single latent symptom dimension that reflects features shared by all mental health disorders, the p factor, is thought to reflect mechanisms that cut across mental disorders. Whether p predicts outcom