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The immune processes associated with atherogenesis have received considerable attention during recent years. IgG FcRs (FcgammaR) are involved in activating the immune system and in maintaining peripheral tolerance. However, the role of the inhibitory IgG receptor FcgammaRIIB in atherosclerosis has not been defined. Bone marrow cells from FcgammaRIIB-deficient mice and C57BL/6 control mice were tra
To improve the accuracy and transferability of molecular mechanics force fields, one needs a simple physical description of intermolecular polarization based on quantum chemistry. Ideally, in the quantum-chemical description, each molecule is treated separately and the interactions with other molecules are included as a perturbation. We propose a simple formulation of this perturbation, viz. to mo
HLA DR4-DQ8 and DR3-DQ2 haplotypes account for 89% of newly diagnosed cases of type 1 diabetes (T1D) in Sweden. The presence of a single copy of DQ6 confers protection. The aim of the present study is to evaluate whether the risk conferred by high risk HLA DR and DQ to T1D is similar in all regions of Sweden and see whether there are any significant regional differences. The subjects comprised 799
The quality of powder is determined by its functionality such as dissolution, encapsulation and flowability. The functionality of powder is in turn determined by their primary properties such as morphology and composition which need to be studied. Hence morphology and surface composition has been largely investigated in spray dried powders and individually dried particles. On the contrary, there i
The post-war years were a time of expansion in Swedish publishing. The economy was growing, people became better educated, the rise of a large middle-class meant new costumers, new publishing and sales strategies added to the increasing market, and overall there was higher sales, more titles published and more people reading. Despite the success story there has been hardly any research done on the
Popular Abstract in Swedish Hemolytiskt uremiskt syndrom (HUS) är den vanligaste orsaken till njursvikt bland barn i västvärlden. HUS kännetecknas av hemolytisk anemi (sönderfall av och brist på röda blodkroppar), trombocytopeni (brist på blodplättar) och akut njursvikt. Den vanligaste formen av sjukdomen, typisk HUS orsakas av Shigatoxinproducerande bakterier, främst olika stammar av EscherichiThis thesis addressed the diagnosis, pathogenesis and clinical course of specific renal diseases hemolytic uremic syndrome (HUS) and dense deposit disease (DDD). HUS may be associated with infection caused by Enterohemorrhagic Escherichia coli (EHEC) or with complement dysfunction due to complement mutations or auto-antibodies (atypical HUS, aHUS). EHEC is a non-invasive highly virulent bacterium
Individual metering and charging (IMC) allows energy costs to be apportioned among tenants in multi-apartment buildings based on their own energy use. This can result in reduced energy use due to an increased saving behaviour by tenants, which has caught the attention of the European Parliament. In the EU-directive 2012/27/EU there is a requirement for IMC to be installed by December 31, 2016 in m
Eiglera flavida and Epilichen scabrosus should be deleted from the Danish checklist. The collections of Caloplaca citrina are revised and most of them referred to C. flavocitrina. Amandinea pelidna, Arthonia peltigerae, A. phaeophysciae, Caloplaca britannica, C. polycarpa, Clauzadea metzleri, Cyphelium karelicum, Dendrophoma lecanorae, Didymellopsis collematum, Endococcus protoblasteniae, Ephebe p
Global cleft surgery missions have provided much-needed care to millions of poor patients worldwide. Still, surgical capacity in low- and middle-income countries is generally inadequate. Through surgical missions, global cleft care has largely ascribed to a vertical model of healthcare delivery, which is disease specific, and tends to deliver services parallel to, but not necessarily within, the l
The use of new powerful nested polymerase chain reaction (PCR) techniques to identify and screen for prevalence of parasites has a huge potential. It allows for the detection and identification of low-intensity infections, but its high sensitivity and technical setup may also induce problems. Here, we report a cautionary note regarding misleading amplification of avian malaria species (Haemoproteu
Narkosläkemedlet racemiskt ketamin är en blandning av lika delar S(+)- och R(–)-ketamin,två spegelvända läkemedelsmolekyler (sk enantiomerer) med något olika effekter.Ketamin började användas på patienter i mitten av 1960-talet och har sedan dess fascineratbåde läkare, forskare och patienter pga sina smärtstillande och sömngivande, menäven hallucinatoriska, effekter. Redan efter några års användniRacemic ketamine, introduced in the mid-sixties, contains equal proportions of the enantiomersS(+)- and R(–)-ketamine. Early clinical reports indicated unfavourable effectson intracranial pressure (ICP) and on the cerebral circulation. Current literature on thistopic is however sparse, and available reports are divergent. The aim of this doctoraldissertation project was to study cerebral and syste
The volume presents the results of an international project carried out in cooperation between the Uppsala University, the Hebrew University in Jerusalem, Lund University and the University of Gothenburg. The questions put forward in the project were: How is hypotaxis marked in Semitic, other than by conjunctions? How does this affect the organization of texts? More specifically, what constitutes
The Department of Physics at Lund University is participating in a European Union project called EUMAPP (European Union Microdose AMS Partnership Programme), in which sample preparation and accelerator mass spectrometry (AMS) measurements of biological samples from microdosing studies have been made. This paper describes a simplified method of converting biological samples to solid graphite for C-
Objective: Previous research has shown that a better therapeutic relationship (TR) predicts more positive attitudes towards antipsychotic medication, but did not address whether it is also linked with actual adherence. This study investigated whether the TR is associated with adherence to antipsychotics in patients with schizophrenia. Methods: 134 clinicians and 507 of their patients with schizoph
