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Serum microRNAs in male subfertility—biomarkers and a potential pathogenetic link to metabolic syndrome
Purpose: The purpose of the study was to identify serum microRNAs providing a link between male subfertility and metabolic syndrome (MetS) and validate their diagnostic potential. Methods: Sera were analyzed for fertility and MetS-related parameters in subfertile men (n = 79) and controls (n = 38). Literature review identified miR-155-5p, miR-122-5p, miR-200a-3p, and miR-200c-3p which previously w
Forests : the cross-linguistic perspective
Do all humans perceive, think and talk about tree cover (‘forests’) in more or less the same way? International forestry programs frequently seem to operate on the assumption that they do. However, recent advances in the language sciences show that languages vary greatly as to how the landscape domain is lexicalized and grammaticalized. Different languages segment and label the large-scale environ
Malaria, Immunity, and Immunopathology
Malaria is a disease spread by mosquitoes, and it is a major global cause of morbidity and mortality. Most of the deaths in malaria are caused by the Apicomplexan parasite Plasmodium falciparum. Immunity against the disease is dependent on repeated exposure, and it usually takes several years to develop. Antibodies against different antigens are an important part of immunity, but cellular immunity
Antibody heavy chain variable domains of different germline gene origins diversify through different paths
B cells produce antibodies, key effector molecules in health and disease. They mature their properties, including their affinity for antigen, through hypermutation events; processes that involve, e.g., base substitution, codon insertion and deletion, often in association with an isotype switch. Investigations of antibody evolution define modes whereby particular antibody responses are able to form
Decontextualisation of Street Art
This chapter discusses the increasing tendency to remove street art from its original site for personal gain. It further explores whether/how copyright claims can be an effective means of preventing such extractions.
New relativistic ANO basis sets for transition metal atoms
New basis sets of the atomic natural orbital (ANO) type have been developed for the first, second, and third row transition metal atoms. The ANOs have been obtained from the average density matrix of the ground and lowest excited states of the atom, the positive and negative ions, and the atom in an electric field. Scalar relativistic effects are included through the use of a Douglas-Kroll-Hess Ha
Regulation of complement activation by C-reactive protein: targeting of the inhibitory activity of C4b-binding protein.
The Swedish experience of rehabilitation robotics
Over the last ten years, there has been a great deal of research and development in Sweden in the field of rehabilitation robotics. The research effort has often focused on workplace adaptations. This paper deals with four robotic adaptations, all of whic
Computer supported visualization to support continuous improvements within quality systems
This paper presents a study wherein computer supported visualization is used to design and enhance understanding of quality systems. The study attempts to discover if a quality system such as ISO 9000 can be visualized, and how the visualization should be designed in order to support continuous improvement. Three companies in southern Sweden have set up special groups (here called design groups) w
Introduction: Unity in Transformation
Preface
‘Imagine all the people sharing all the rights’: The application of the United Nations Convention on the Rights of Persons with Disabilities in the practice of the European Court of Human Rights with a focus on the right to vote
The thesis covers human rights violations against persons with disabilities, focusing on their right to political life and the right to vote, using the framework of critical disability theory. The aim of the thesis is two-folded: it analyses the use of the UN Convention on the Rights of Persons with Disabilities (CRPD) in the adjudication of the European Court of Human Rights (ECtHR) with a focus
Judges Assessing the Independence of Judges. Historical Foundations and Practical Procedures in Facing the Threats against the Rule of Law in Europe
The existence of impartial and independent courts is a cornerstone of the success of the European project. The recent renaissance of “illiberal States” jeopardises the application of the rule of law and risks destroying the foundations of the EU legal order. In 2018, the Court of Justice of the European Union (CJEU) began developing two new lines of case-law. Firstly, the CJEU found itself to be c
Cancer incidence in a male adult population in relation to estimated protracted colon dose – A nested case control study in Northern Sweden after the Chernobyl Nuclear Power Plant accident
Introduction: Uncertainty in the dose-response of low dose radiation raised concern of an increased cancer incidence in Sweden after the Chernobyl Nuclear Power Plant (NPP) accident. Material and methods: A closed cohort was created of all males ≥18 years of age living in the Northern Sweden in 1986. In total 826,400 individuals were enrolled including 40,874 hunters. A nested case-control design
From giant clumps to clouds-III. The connection between star formation and turbulence in the ISM
Supersonic gas turbulence is a ubiquitous property of the interstellar medium. The level of turbulence, quantified by the gas velocity dispersion (σg), is observed to increase with the star formation rate (SFR) of a galaxy, but it is yet not established whether this trend is driven by stellar feedback or gravitational instabilities. In this work, we carry out hydrodynamical simulations of entire d
Aspects of early interventions in out-of-hospital cardiac arrest
MHC class II genotype-by-pathogen genotype interaction for infection prevalence in a natural rodent-Borrelia system
A pilot study of methods for prediction of poor outcome by head computed tomography after cardiac arrest
Introduction: In Sweden, head computed tomography (CT) is commonly used for prediction of neurological outcome after cardiac arrest, as recommended by guidelines. We compare the prognostic ability and interrater variability of routine and novel CT methods for prediction of poor outcome. Methods: Retrospective study including patients from Swedish sites within the Target Temperature Management afte
The effect of metamorphism on the aggregate properties of gabbroic rocks
Granitic rocks are durable materials sought after for the production of road and railroad aggregates. Granitic bedrock commonly, however, includes gabbroic components, which may enhance or decrease the aggregate performance. This study evaluates the variation in resistance to fragmentation (Los Angeles value, LA) and wear/abrasion (micro-Deval value, MDE) for the fraction 10/14 mm of gabbro in dif
