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Identification and qualitative characterization of high and low lignin lines from an oat TILLING population

To identify differences in seed lignin content, 520 randomly chosen independent lines were screened in mutagenized oat population and lines with the seed lignin levels ranging from 20 to 63 gkg(-1) were identified. In the commercial variety Belinda, from which the mutated population was developed, seed lignin level was determined to be 41 g kg(-1). In Assiniboia, a Canadian low lignin variety, it

Analysing analyses-An approach to combining several risk and vulnerability analyses

The Swedish county council Region Skane is developing work processes for iterative risk and vulnerability analyses. This will be arranged in a distributed bottom-up manner, where analyses are performed and results reported through three hierarchical levels, ending at a central unit within the county council organisation. That unit is responsible for three tasks: 1) Establish a summary of the risks

Increasing Incidence of Young-Onset Colorectal Carcinoma A 3-Country Population Analysis

BACKGROUND: The overall incidence of colorectal carcinoma is declining in Western populations; however, single country series demonstrate an increase in young-onset (<50 years) colorectal carcinoma. OBJECTIVE: The purpose of this study was to determine whether the pattern of increasing incidence of young-onset colorectal carcinoma is consistent across 3 Western populations. DESIGN: This is a popul

Circulating Levels of Brain-Enriched MicroRNAs Correlate with Neuron Specific Enolase after Cardiac Arrest-A Substudy of the Target Temperature Management Trial

Outcome prognostication after cardiac arrest (CA) is challenging. Current multimodal prediction approaches would benefit from new biomarkers. MicroRNAs constitute a novel class of disease markers and circulating levels of brain-enriched ones have been associated with outcome after CA. To determine whether these levels reflect the extent of brain damage in CA patients, we assessed their correlation

Anatomy of a 21st-century project: A critical analysis

In this analytical chapter we focus on human factors to shed light on what a 21st-century project might look like from within. Adopting a non-essentialist perspective to project-making, we at the same time acknowledge that the notion of human nature is blurred, dynamic, changeable, heterogeneous, and internally riven. The human condition, hence, always dictates what ontological position a project

Survival and synergistic growth of mixed cultures of bifidobacteria and lactobacilli combined with prebiotic oligosaccharides in a gastrointestinal tract simulator.

Probiotics, especially in combination with non-digestible oligosaccharides, may balance the gut microflora while multistrain preparations may express an improved functionality over single strain cultures. In vitro gastrointestinal models enable to test survival and growth dynamics of mixed strain probiotics in a controlled, replicable manner.

Inhibition of metastasis in a castration resistant prostate cancer model by the quinoline-3-carboxamide tasquinimod (ABR-215050)

BACKGROUND Tasquinimod (ABR-215050) is an orally active quinoline-3-carboxamide analog that has completed phase II clinical trial in patients with castration resistant prostate cancer, showing promising inhibiting effects on the occurrence of metastasis and delayed disease progression. Its mechanism of action is not fully elucidated, but previous studies show anti-angiogenic effects and strong int

Self-Assembly and Formation of Chromonic Liquid Crystals from the Dyes Quinaldine Red Acetate and Pyronin Y

The aqueous self-assembly behavior of the dyes Quinaldine red acetate and Pyronin Y in a wide range of concentrations is reported here for the first time. 1H NMR spectroscopy, polarized-light optical microscopy, and small and wide X-ray scattering were used to get insight into molecular interactions, phase boundaries and aggregate structure. Quinaldine red acetate and Pyronin Y self-organize into

The Collective Voice Legitimation Strategies in Focus Group Discussions with Nurses in Municipal Palliative Care for Older People in Sweden

This paper explores focus group discussions of registered nurses in municipal palliative care for older people, using data collected by researchers with an interest in health sciences. The linguisti- cally based discourse analyis builds on a combi- nation of Bakhtinian notions of dialogicity, the Other and addressivity, the use of quotations, and also van Leeuwen’s framework for legitima- tion in

The emerging complexity of gene fusions in cancer.

Structural chromosome rearrangements may result in the exchange of coding or regulatory DNA sequences between genes. Many such gene fusions are strong driver mutations in neoplasia and have provided fundamental insights into the disease mechanisms that are involved in tumorigenesis. The close association between the type of gene fusion and the tumour phenotype makes gene fusions ideal for diagnost

Projected Rotational Velocities and Stellar Characterization of 350 B Stars in the Nearby Galactic Disk

Projected rotational velocities (v sin i) are presented for a sample of 350 early B-type main-sequence stars in the nearby Galactic disk. The stars are located within similar to 1.5 kpc from the Sun, and the great majority within 700 pc. The analysis is based on high-resolution spectra obtained with the MIKE spectrograph on the Magellan Clay 6.5 m telescope at the Las Campanas Observatory in Chile

Nucleolar proteins with altered expression in leukemic cell lines.

The function of the nucleolus is intimately connected to cell proliferation, division and growth. Many cancer cells have enlarged nucleoli, and several nucleolar proteins have been linked to tumorigenesis. In order to find proteins whose expression is altered in the nucleoli of leukemic cells, we carried out two-dimensional difference gel electrophoresis (2-D DIGE) analyses. Prohibitin (PHB) and T

3D Archaeology at Çatalhöyük

The project “3D-Digging at Çatalhöyük” began in 2010 thanks to collaboration between Stanford University (Archaeological Center) and the University of California Merced with the scope to record, document (with different digital technologies) and visualize in virtual reality all the phases of archaeological excavation. Phase I (2010 excavation season) of the project was mainly oriented to test diff

Crime Tourism and the Branding of Places

My paper will focus on the expanding tourism connected to popular crime novels in Sweden. The Swedish crime genre has been exploding during the last decades, and several Swedish crime writers have had an immense success abroad, e. g. Henning Mankell, Liza Marklund and Karin Alvtegen. Some of these writers have chosen to connect their stories to a specific place or region; a fact, which has been ex

Simulation of Human-Vehicle Interaction in Vehicle Design at Saab Automobile: Present and Future

Developers, reviewers and users of human simulation tools claim that the use of these tools may reduce development time and development cost. However, before these benefits will be fully visible, there are some barriers to overcome. The aims of this case study are to identify which departments at Saab Automobile use some sort of human simulation tool today, and to identify the information flow and

The Moral Side of M&A: Changing Morale Reflecting Moral Change?

Is personnel resistance in deed as dysfunctional as it is assumed to be, in M&A theory? According to Hirschman (1970), voice is more loyal than exit, implying that employees telling their opinion should be understood as a sign of loyalty, rather than a problem. An important aspect of loyalty is its moral basis. Scanning M&A literature, it becomes evident that very little has been written o

The Effect of a Massive Wage Push on Income Distribution and Employment. Evidence from the 1920 Eight-Hour Workday Reform in Sweden and Its Aftermath

In 1920, the working day in Swedish industry and services was cut from 10 to 8 hours without wages being cut correspondingly. This change resulted in a dramatic wage push, with real wages increasing by about 50 percent in the years from 1919 to the deflation of 1921–22. This paper studies the consequences of this wage push for real wages, unemployment, profits and investments. Since agriculture wa