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Out with the new, in with the old! Revitalizing existing communities for sustainability and subjective wellbeing

Urbanisation as a megatrend shows no signs of weakening globally, or in the Nordic countries. At the same time, the overwhelming majority of environmental impacts are generated in cities. This derives from the economic growth generated by cities, as the decoupling of economic activity from environmental impacts has not been successful to date. Moreover, from a built environment perspective, urbani

Children with Hirschsprung's Disease and Syndromes with Cognitive Dysfunction : Manifestations, Treatment, and Outcomes

Introduction To assess differences in initial symptoms, treatments, and bowel function between children with Hirschsprung's disease (HD) with or without a cognitive dysfunction (CD). Materials and Methods The study included children with HD who underwent transanal endorectal pull-through. A retrospective chart review was performed to collect data on patient characteristics, diagnosis, and treatmen

Ezh2 Represses Transcription of Innate Lymphoid Genes in B Lymphocyte Progenitors and Maintains the B-2 Cell Fate

Lymphocyte lineage specification and commitment requires the activation of lineage-specific genes and repression of alternative lineage genes, respectively. The mechanisms governing alternative lineage gene repression and commitment in lymphocytes are largely unknown. In this study, we demonstrate that Ezh2, which represses gene expression through methylation of histone 3 lysine 27, was essential

Programmables self-supporting structures through 4D printing on tensioned textiles

4D printing is a development in additive manufacturing that enables 3D printed objects to transform over time in response to environmental stimuli. This research investigates the architectural viability of large-scale fused deposition modeling (FDM) 3D printing of thermoplastics onto stretched textiles, which retract and warp into 3D structures upon release. Employing an iterative research-by-desi

How complex are galaxies? A non-parametric estimation of the intrinsic dimensionality of wide-band photometric data

Galaxies are complex objects, yet the number of independent parameters to describe them remains unknown. We present here a non-parametric method to estimate the intrinsic dimensionality of large data sets. We apply it to wide-band photometric data drawn from the COSMOS2020 catalogue and a comparable mock catalogue from the HORIZON-AGN simulation. Our galaxy catalogues are limited in signal-to-nois

Molecular analysis of acute pyelonephritis—excessive innate and attenuated adaptive immunity

This study investigated the molecular basis of disease severity in acute pyelonephritis (APN), a common and potentially life-threatening bacterial infection. Two cohorts of infants with febrile urinary tract infection were included. Renal involvement was defined by DMSA scans and molecular disease determinants by gene expression analysis and proteomic screens, at diagnosis and after 6 mo. Innate i

Decoding sex differences in human immunity through systems immunology

Immune function varies widely across humans. Biological sex is a key factor underlying human immune variability, with men presenting with more severe infections and increased cancer rates, while women exhibit higher vaccine responses and prevalence of autoimmunity. Intrinsic biological sex differences arise from varying contributions of chromosomal sex, and sex hormone sensing and downstream signa

Learning from informal settlements : the case of Guayaquil

Informal settlements often appear chaotic, seeming perhaps to have emerged without any planning. Evidence suggests however that many slum areas are in fact the result of organized, structured processes carried out with discipline and precision. Formal and informal settlements coexist parallel to one another without significant interaction, and governments and informal planners rarely understand ea

Sternal opening width is associated with increased risk for capillary leak syndrome and death in neonates and infants after cardiac surgery with delayed sternal closure

Capillary leak syndrome is a serious postoperative complication in neonates and infants after open-heart surgery for CHD. The aim of this study was to investigate the relationship between sternal opening width and the occurrence of capillary leak syndrome in patients undergoing cardiac surgery with delayed sternal closure.We retrospectively analysed the clinical data of neonates and infants (aged

Det intellektuella kapitalet - Hur hanterar företag dessa viktiga tillgångar?

Då det intellektuella kapitalet utgör en viktig del av ett företags totala tillgångar, har vi valt att undersöka hur hanteringen och styrningen av detta kapital ser ut i verkligheten. Dessutom ville vi se om våra undersökningsföretag skulle kunna förbättra sin hantering av IK genom att tillämpa de modeller som finns på området. De modeller vi valt att titta närmare på är Skandia Navigator, The Int

Multiple populations in globular clusters : The distinct kinematic imprints of different formation scenarios

Several scenarios have been proposed to explain the presence of multiple stellar populations in globular clusters. Many of them invoke multiple generations of stars to explain the observed chemical abundance anomalies, but it has also been suggested that self-enrichment could occur via accretion of ejecta from massive stars on to the circumstellar disc of low-mass pre-main sequence stars. These sc

Accuracy in a finite volume godunov type method

The standard Godunov type method used in computational fluid dynamics shows accuracy problems for low Mach number flows and for the kinetic energy at the highest wave numbers resolvable on a given grid. Both drawbacks become visible when simulating the decay of isotropic turbulence at the low Mach numbers typical for the respective experimental investigations. A modification to cure both problems

Chemical composition and in vitro starch bioavailability of Phaseolus vulgaris (L) cv Mayocoba

Common beans of the Mayocoba variety were cooked (178 min) and evaluated regarding their chemical composition and starch digestibility in vitro. Mean physical characteristics of the Mayocoba grain were: thousand-kernel weight, 443.0 (±0.98)g; length, 12.45mm; width 7.84mm and thickness, 6.44mm. Total starch content in Mayocoba bean was 40.24% (dmb). The available starch was 22.87%, whereas resista