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Influence of ionic surfactants on the aggregation of poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) block copolymers studied by differential scanning and isothermal titration calorimetry

The interaction between three triblock copolymers of poly(ethylene oxide) and poly(propylene oxide), EOnPOmEOn, and the ionic surfactants sodium dodecyl sulfate, SDS, and hexadecyltrimethylammonium chloride, CTAC, has been studied in dilute aqueous solution using differential scanning calorimetry, DSC, and isothermal titration calorimetry. The length of the PPO block was the same in all three copo

Novel quantitative trait Loci controlling development of experimental autoimmune encephalomyelitis and proportion of lymphocyte subpopulations.

The B10.RIII mouse strain (H-2r) develops chronic experimental autoimmune encephalomyelitis (EAE) upon immunization with the myelin basic protein 89–101 peptide. EAE was induced and studied in a backcross between B10.RIII and the EAE-resistant RIIIS/J strain (H-2r), and a complete genome scan with microsatellite markers was performed. Five loci were significantly linked to different traits and cli

Additive effects of leflunomide and tacrolimus in prevention of islet xenograft rejection

Leflunomide is a low molecular weight immunosuppressive drug which inhibits the enzymes dehydroorotate dehydrogenase and protein tyrosine kinase, both of which are important components in the immune response. As the mechanisms of action of leflunomide and tacrolimus are different, we postulated an additive or synergistic effect of the two drugs and investigated the effects of leflunomide alone, or

Effect of spatially distributed hydrophobic surface residues on protein-polymer association

The effect of the spatial distribution of hydrophobic surface residues on the adsorption of a weakly hydrophobic polymer to proteins has been examined using a coarse-grain model solved by Monte Carlo simulations. A given number of surface sites were distributed randomly on the protein surface subjected to a distance constraint. Five protein classes for which the minimum distance between the sites

Biological and molecular evidence for existence of lymphoid-primed multipotent progenitors

Studies from our and other laboratories have over the last 2 years implicated the existence of multipotent progenitors (MPPs) with combined granulocyte-macrophage, B cell, and T cell potential, but little or no megakaryocyte-erythroid (MkE) potential in the adult bone marrow Lineage (-)SCA-1 +KIT+ (LSK) compartment of multipotent stem and progenitor cells. The evidence for the existence of LSKCD34

Terapi, upplysning, kamp och likhet till varje pris - undervisningsideologier och diskurser hos lärare och lärarstuderande i musik

This study is the second part of a larger work with the purpose to distinguish, describe and discuss the discourses around music education in school. The first part focused on how adolescents in secondary school talk abot music education, and the second part is concerned with teaching ideologies and discources among teachers and teacher education students. An overarching purpose of the two studies

On the origin of red giant depletion through low-velocity collisions

We investigate a means of explaining the apparent paucity of red giantstars within post-core-collapse globular clusters. We propose thatcollisions between the red giants and binary systems can lead to thedestruction of some proportion of the red giant population, by eitherknocking out the core of the red giant or by forming a common envelopesystem which will lead to the dissipation of the red gian

Reducing Memory in Software-Based Thread-Level Speculation for JavaScript Virtual Machine Execution of Web Applications

Thread-Level Speculation has been used to take advantage of multicore processors in virtual execution environments for the sequential JavaScript scripting language. While the results are promising the memory overhead is high. Here we propose to reduce the memory usage by limiting the checkpoint depth based on an in-depth study of the memory and execution time effects. We also propose an adaptive h

Interlaboratory tests on thermal foot models

A limited Round Robin test has been carried out with different types of foot models. Eight laboratories carried out the tests. The foot models varied in sizes from 254 to 275 mm, representing boot sizes from 41 to 44. Tests with both a bare foot and sock were carried out at about +20 °C and 50% RH. The boots, a thin rubber and a winter boot, were tested at about +5 °C and 85% RH. The conditioning

Properties of the -513 km/s Ejecta in the Spectrum of Eta Carinae

In the spectral region 2400-3160A of Eta Carinae, we have identifiedapproximately 500 absorption lines each with up to twenty velocitycomponents.The -512 km/s component is truely unique as 1) the typicalline width is <3 km/s, 2) the identified lines are in Fe I, Fe II, VII and Ti II, and 3) the lines originate from lower levels up to 2000cm-1 above the ground level. We have measured the velocity c

Time-resolved and steady-state fluorescence studies of hydrophobically modified water-soluble polymers

A comprehensive study of the photophysical behavior of poly(acrylic acids) randomly labeled with pyrene using steady-state and time-resolved fluorescence spectroscopy is presented. The influence of external factors, such as different solvents and pH in the aqueous solution, on the polymer photophysics has been investigated. These factors induce major changes in the polymer conformation, which are