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Multiple independent IgE epitopes on the highly allergenic grass pollen allergen Phl p 5.

Background Group 5 allergens are small proteins that consist of two domains. They belong to the most potent respiratory allergens. Objective To determine the binding sites and to study allergic patients' IgE recognition of the group 5 allergen (Phl p 5) from timothy grass pollen using human monoclonal IgE antibodies that have been isolated from grass pollen allergic patients. Methods Using recom

A finite deformation continuum modelling framework for curvature effects in fibre-reinforced nanocomposites

Motivated by experimental findings on one-dimensional nano-materials, this contribution focusses on the elaboration of a fibre curvature based higher-order gradient contribution to the stored energy function in a finite deformation setting. The presented approach is based on the fundamental theoretical developments for fibre-reinforced composites presented by Spencer and Soldatos (2007), which tak

Familial associations between autoimmune hepatitis and primary biliary cholangitis and other autoimmune diseases

Autoimmune hepatitis (AH) and primary biliary cirrhosis (PBC) are autoimmune diseases (AIDs) targeting cellular components of the liver. Being rare diseases, limited data are available about familial risks among these AIDs (concordant) or between them and other AIDs (discordant). We aimed to carry out an unbiased study on these AIDs based on medically diagnosed patients. We collected data on patie

Mid-infrared laser-induced thermal grating spectroscopy of hot water lines for flame thermometry

In this work we report the impact of using mid-infrared laser-induced thermal grating spectroscopy (IRLITGS) for temperature measurements in flames by probing hot water lines. The measurements have been performed in the product zone of laminar atmospheric CH 4 /H 2 /air flat flames with equivalence ratio ranging between 0.6 and 1.05. LITGS is a technique based on thermalization through collisions

Reporting frequency of radiology findings increases after introducing visual rating scales in the primary care diagnostic work up of subjective and mild cognitive impairment

Objectives: Study the effect of introducing a template for radiological reporting of non-enhanced computed tomography (NECT) in the primary care diagnostic work up of cognitive impairment using visual rating scales (VRS). Methods: Radiology reports were assessed regarding compliance with a contextual report template and the reporting of the parameters medial temporal lobe atrophy (MTA), white matt

Therapeutic hypothermia for comatose survivors after near-hanging-A retrospective analysis

BACKGROUND: Patients who survive after suicidal hanging attempts suffer from transient brain ischaemia. Morbidity and mortality is high, and no specific therapy is available. Hypothermia attenuates ischaemic brain damage and has become standard care in comatose survivors of cardiac arrest; therapeutic hypothermia may thus be useful for near-hanging victims as well.OBJECTIVES: To perform a literatu

Cross-reactivity between immune responses to Helicobacter bilis and Helicobacter pylori in a population in Thailand at high risk of developing cholangiocarcinoma

Helicobacter bilis DNA has been detected in human tissue and is a candidate for etiologic investigations on the causes of hepatic and biliary tract diseases, but reliable serologic tests need to be developed in order to pursue such investigations. The scope of this study was to assess the specificity of two assays for H. bilis immune response allowing for H. pylori, and their cross-reactivity in a

Radially resolved simulations of collapsing pebble clouds in protoplanetary discs

In the Solar System, asteroids and Kuiper belt objects as well as comets are remnant planetesimals from the time of planet formation. Interactions between solids and gas inside a protoplanetary disc can, e.g. through the streaming instability, form gravitationally bound planetesimal-mass clouds of pebbles. Such clouds will inevitably have inelastic collisions between pebbles, lose energy and exper

A Simple Model for Harmonics in Electrical Distribution Networks

A modularized approach to modeling of harmonics in electrical distribution networks at steady state is presented. It is based on harmonic balance and exploits that the loads in a distribution network are connected in parallel in such a way that their operating conditions are approximately known in advance (e.g. 230 V, 50 Hz) and the harmonic distortion of the voltage is limited. The model for a co

Instantaneous 3D imaging of flame species using coded laser illumination

Three-dimensional (3D) imaging of dynamic objects that rapidly undergoes structural changes, such as turbulent combusting flows, has been a long-standing challenge, mainly due to the common need for sequential image acquisitions. To accurately sense the 3D shape of the sample, all acquisitions need to be recorded within a sufficiently short time-scale during which the sample appears stationary. He

Survival of habitable planets in unstable planetary systems

Many observed giant planets lie on eccentric orbits. Such orbits could be the result of strong scatterings with other giant planets. The same dynamical instability that produces giant planet scatterings can also alter the orbits of terrestrial planets. For example, a habitable rocky planet in the system can be ejected or transported to an orbit outside the habitable zone. Therefore, there is a lin

Qualitative questionnaires as a method for information studies research

Introduction. We present qualitative questionnaires, originally an ethnological method for documenting and collecting material about everyday life, as a fruitful method for information studies. Method. Since the early 20th century qualitative questionnaires, on various themes, have been sent out to informants. The answers to qualitative questionnaires consist of memories, opinions and experiences.