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A gluten free diet lowers NKG2D and ligand expression in BALB/c and NOD mice.

The interplay between diet and immune-parameters which could affect type 1 diabetes (T1D) pathogenesis is not sufficiently clarified. Intestinal upregulation of the activating receptor NKG2D(CD314) and its ligands is a hallmark of celiac disease (CD). However, the direct effect of gluten on NKG2D expression is not known. We studied, by FACS (lymphoid tissues) and RT-qPCR (intestine and pancreatic

Multiple independent IgE epitopes on the highly allergenic grass pollen allergen Phl p 5.

Background Group 5 allergens are small proteins that consist of two domains. They belong to the most potent respiratory allergens. Objective To determine the binding sites and to study allergic patients' IgE recognition of the group 5 allergen (Phl p 5) from timothy grass pollen using human monoclonal IgE antibodies that have been isolated from grass pollen allergic patients. Methods Using recom

Therapeutic hypothermia for comatose survivors after near-hanging-A retrospective analysis

BACKGROUND: Patients who survive after suicidal hanging attempts suffer from transient brain ischaemia. Morbidity and mortality is high, and no specific therapy is available. Hypothermia attenuates ischaemic brain damage and has become standard care in comatose survivors of cardiac arrest; therapeutic hypothermia may thus be useful for near-hanging victims as well.OBJECTIVES: To perform a literatu

Cross-reactivity between immune responses to Helicobacter bilis and Helicobacter pylori in a population in Thailand at high risk of developing cholangiocarcinoma

Helicobacter bilis DNA has been detected in human tissue and is a candidate for etiologic investigations on the causes of hepatic and biliary tract diseases, but reliable serologic tests need to be developed in order to pursue such investigations. The scope of this study was to assess the specificity of two assays for H. bilis immune response allowing for H. pylori, and their cross-reactivity in a

Integritetsfrågor i arbetslivet

Popular Abstract in Swedish Denna avhandling behandlar ämnesområdet integritet i arbetslivet. Individer i ett modernt samhälle har anspråk på respekt eller icke angrepp inom sitt intresseområde. Arbetslivet utgör ett exempel på ett sådant område. Min utgångspunkt då jag behandlar ämnet är främst individens (arbetstagarens) prima-facie anspråk på respekt, icke angrepp inom sitt intresseområde. IntThis dissertation deals with personal privacy in working life. Humans have legitimate expectations and claims to respect for and non-interference with personal privacy in many areas and stages of life. The work place is just one of them. The point departure when dealing with privacy matters at the workplace is primarily the claim by individual employees to respect for and non-interference with the

Transition probabilities and lifetimes in singly ionized rhenium

Transition probabilities and radiative lifetimes have been obtained for 45 transitions of Re II using a combination of radiative lifetime values obtained with the laser-induced fluorescence technique ( seven levels) and theoretical branching fractions. This new set of results, concerning ultraviolet and visible lines, will be useful in the future for investigating the composition of chemically pec

Bactericidal activity of human eosinophilic granulocytes against Escherichia coli

Eosinophils participate in allergic inflammation and may have roles in the bodys defense against helminthic infestation. Even under noninflammatory conditions, eosinophils are present in the mucosa of the large intestine, where large numbers of gram-negative bacteria reside. Therefore, roles for eosinophils in host defenses against bacterial invasion are possible. In a system for bacterial viable

Mid-infrared laser-induced thermal grating spectroscopy of hot water lines for flame thermometry

In this work we report the impact of using mid-infrared laser-induced thermal grating spectroscopy (IRLITGS) for temperature measurements in flames by probing hot water lines. The measurements have been performed in the product zone of laminar atmospheric CH 4 /H 2 /air flat flames with equivalence ratio ranging between 0.6 and 1.05. LITGS is a technique based on thermalization through collisions

Reporting frequency of radiology findings increases after introducing visual rating scales in the primary care diagnostic work up of subjective and mild cognitive impairment

Objectives: Study the effect of introducing a template for radiological reporting of non-enhanced computed tomography (NECT) in the primary care diagnostic work up of cognitive impairment using visual rating scales (VRS). Methods: Radiology reports were assessed regarding compliance with a contextual report template and the reporting of the parameters medial temporal lobe atrophy (MTA), white matt

Effect of symmetrical restoration for the migration of uncemented total hip arthroplasty : A randomized RSA study with 75 patients and 5-year follow-up

Background: Inferior placement of a femoral stem is predictive for early loosening and failure, but does restoration of the original hip anatomy benefit the function and survival of a total hip replacement? Methods: Seventy-five patients with primary unilateral hip osteoarthritis operated with an uncemented anatomical stem were randomized for either standard or modular stems. We used 50 ABG II ste

Personal History of Diabetes as Important as Family History of Colorectal Cancer for Risk of Colorectal Cancer : A Nationwide Cohort Study

INTRODUCTION: Diabetes mellitus (DM) and colorectal cancer (CRC) share some risk factors, including lifestyle and metabolic disturbances. We aimed to provide in-depth information on the association of CRC risk, especially early-onset CRC, with DM, family history of CRC, and age at DM diagnosis. METHODS: A nationwide cohort study was conducted using Swedish family cancer data sets, inpatient, and o

Runaway and walkaway stars from the ONC with Gaia DR2

Theory predicts that we should find fast, ejected (runaway) stars of all masses around dense, young star-forming regions. N-body simulations show that the number and distribution of these ejected stars could be used to constrain the initial spatial and kinematic substructure of the regions. We search for runaway and slower walkaway stars within 100 pc of the Orion Nebula Cluster (ONC) using Gaia D