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Runaway stars masquerading as star formation in galactic outskirts

In the outskirts of nearby spiral galaxies, star formation is observed in extremely low gas surface densities. Star formation in these regions, where the interstellar medium is dominated by diffuse atomic hydrogen, is difficult to explain with classic star formation theories. In this letter, we introduce runaway stars as an explanation for this observation. Runaway stars, produced by collisional d

Generation of the human pluripotent stem-cell-derived astrocyte model with forebrain identity

Astrocytes form functionally and morphologically distinct populations of cells with brain-region-specific properties. Human pluripotent stem cells (hPSCs) offer possibilities to generate astroglia for studies investigating mechanisms governing the emergence of astrocytic diversity. We established a method to generate human astrocytes from hPSCs with forebrain patterning and final specification wit

Male Sex Work in Sweden: Criminalization of the Client

The chapter engages with the so-called Swedish Model in the country of its invention: Sweden. First, it examines feminist thought that has supported the implementation of this legislation. Next, it looks at the effects of this law according to 12 key informants and 25 male sex workers. Ultimately, the criminalization of sex work in Sweden is so focused on women selling sex to men that police and p

Blue tit Cyanistes caeruleus males increase their reproductive effort when subject to a flea experimental manipulation

Parasites exert a strong selection pressure on their hosts as manifested in behavioural antiparasite traits to reduce negative impacts on fitness. The numerous nest-dwelling ecto-parasites residing in avian nests make altricial birds excellent model-systems for investigating the relationship between parasites and their hosts. Here, we experimentally increased natural levels of hen fleas Ceratophyl

Hidden Attractions of Administration : The Peculiar Appeal of Meetings and Documents

This book argues that the expansion of administrative activities in today’s working life is driven not only by pressure from above, but also from below. The authors examine the inner dynamics of people-processing organizations — those formally working for clients, patients, or students — to uncover the hidden attractions of doing administrative work, despite all the complaints and laments about ‘t

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Nya studier visar att elever ofta ignorerar feedback. Samtidigt vet vi att feedback är centralt för lärande. För att förstå vad som händer måste vi betrakta feedback som en sammanhängande process i flera steg av uppmärksamhet, tolkning, förståelse och användning. Detta i motsats till en traditionell modell som endast betraktar den feedback som ges (input) och elevens motsvarande prestation (output

Collagen-induced arthritis development requires alpha beta T cells but not gamma delta T cells: studies with T cell-deficient (TCR mutant) mice

Collagen type II (CII)-induced arthritis (CIA) in mice is a model for rheumatoid arthritis (RA) in which the role of T lymphocytes remains controversial. To clarify this, we have bred a targeted gene deletion of TCR beta or delta loci into two mouse strains susceptible to CIA, the B10.Q and DBA/1 strains. The TCRbeta-/- mice lacked alphabeta T cells, which was compensated by an expansion of B cell

Non-Major Histocompatibility Complex dependent variations in lymphocyte activity between inbred mouse strains susceptible to various autoimmune diseases

Transgenic techniques in inbred mouse strains are powerful tools to investigate the specific roles of genes in biological pathways and disease models. However, there is increasing concern over the influence of a variable genetic background in such experiments. To date there have been few investigations of the immunological differences between inbred mouse strains used in models of autoimmune disea

Unpacking (Ir)regular Labour Migration

This chapter unpacks the complex and contested nature of ‘irregular labour migration’ and explores the meaning and analytical rigour of this conceptualisation. We discuss four social positions: 1) authorised migrant regular worker, 2) authorised migrant irregular worker, 3) unauthorised migrant irregular worker and 4) unauthorised migrant regular worker. Using the distinctions between informalisat

The Late Emergence of the Socioeconomic Gradient in Adult Mortality: An Urban Phenomenon?

Previous research has shown that class differences in adult mortality in the study area emerged only in the mid-twentieth century. Such findings question a universal association between socioeconomic status and mortality. This chapter examines whether these class differences in adult mortality emerged at the same time in urban as in rural areas. The analysis shows that the social class gradient in

Social Media, Anti-Corruption Activism and Democratisation in Authoritarian Contexts : A Case Study of Uzbekistan

This article aims to examine the nexus between social media, anti-corruption activism and democratisation in authoritarian regime contexts. It will investigate the complex ways in which civil society actors utilise art and humour on social media platforms to engage in covert anti-corruption activism. In doing so, we will show how, in authoritarian contexts, digital (social media) activists creativ

Higher-order thinking e-assessment in online EFL courses : Swedish instructors' perceptions and experiences

Previous research indicates that higher-order thinking skills (HOTS) have an important role in L2 learning. In an online learning context, e-assessment tasks are ideally designed to target these skills. A recently conducted study by Johansson (2020) indicates that HOTS e-assessment is relatively common in Swedish online English as a Foreign Language (EFL) courses. Generally, instructors’ perceptio

Completion axillary lymph node dissection for the identification of pN2–3 status as an indication for adjuvant CDK4/6 inhibitor treatment : a post-hoc analysis of the randomised, phase 3 SENOMAC trial

Background: In luminal breast cancer, adjuvant CDK4/6 inhibitors (eg, abemaciclib) improve invasive disease-free survival. In patients with T1–2, grade 1–2 tumours, and one or two sentinel lymph node metastases, completion axillary lymph node dissection (cALND) is the only prognostic tool available that can reveal four or more nodal metastases (pN2–3), which is the only indication for adjuvant abe

Stimulation of χ transcription by a decamer‐dependent, synergistic mechanism

The intact SP6 χ promoter stimulated transcription 30 times more efficiently than did a control promoter consisting of a TATA motif as the only promoter element. Mutation of the SP6 χ promoter decamer in two positions reduced the transcriptional stimulation activity by over 90%. Promoters containing the SP6 χ promoter octamer or a consensus octamer in front of a TATA box were ineffective immunoglo