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The paper presents a computer-based decision support system for watershed planning and flood design purposes including a conceptual rainfall-runoff model. The software package uses up-to-date programing techniques in Windows environment which makes it flexible to handle, adaptable to new areas, and easy to test for different design criteria. The package is suitable for design problems in small as
CONTEXT: Pharmacodynamic studies have shown that persistently high platelet reactivity is common in patients with diabetes in spite of clopidogrel treatment. Clinical trials have not convincingly demonstrated that clopidogrel benefits patients with diabetes as much patients without diabetes.OBJECTIVES: To estimate the clinical effectiveness associated with clopidogrel treatment after myocardial in
In evaluating the effectiveness of a road safety treatment, the regression to the mean phenomenon is a cause for concern because of a possible overestimation of benefits. Therefore, Bayesian approaches are usually suggested as the most appropriate methodologies for before—after studies as they account for regression to the mean effects. The empirical Bayes (EB) methodology examines the estimation
Objective: To investigate the relationship between meniscus magnetic resonance (MR) relaxation parameters and meniscus degradation through quantitative imaging of ex vivo posterior horns of menisci from subjects with and without knee osteoarthritis (OA). Design: We sampled medial and lateral menisci from ten medial compartment knee OA patients (mean age 63 years) undergoing total knee replacement
This project consists of a thorough study of an energy efficient and moisture safe row-house, located in the Nordic climate of Sweden. Climate and site analysis, building scale design decisions and finally the evaluation and optimization of its energy performance were different steps of a holistic process aiming at the architectural quality, energy efficiency, comfort and the well-being of users.
From the 1880s until the ban of this practice in the 1970s, German vacationers built sandcastles, some of which were artfully decorated and awarded prizes in competitions by the spa administrations. Research regards this as a manifestation of a ‘typical German’ national character. The article counters this approach with an interpretation that understands sandcastles as metaphors for typical charac
High and low molecular mass kininogen, two multidomain plasma proteins, bind to endothelial cells, platelets, and neutrophils in the intravascular compartment. The specific cell attachment site on their common heavy chain is mediated by domain-3, a cystatin-like structure with inhibitory capacity for papain-like proteinases (Jiang, Y., Muller-Esterl, W., and Schmaier, A. H. (1992) J. Biol. Chem. 2
Transforming growth factor-α (TGF-α) exerts several effects on target cells, such as neovascularization promotion and mitogenic signalling. Using immunoelectron microscopy, we show that monocytes and neutrophils, store TGF- α in cytoplasmic granules. In monocytes, TGF-α did not colocalize with components of peroxidase-positive granules or with albumin of secretory vesicles. Furthermore, no colocal
The objective of this study was to investigate whether the superantigen staphylococcal enterotoxin A (SEA), which binds to HLA class II and T-cell receptor Vβ chains, can direct cytotoxic T cells to lyse cytokine-stimulated endothelial cells (EC). In addition, we wanted to determine whether SEA- primed cytotoxic T cells could be targeted to EC surface molecules as a means of a novel cancer immunot
The fundamental first stage of product interaction is through sensory perception, which generates cognitive and affective experiences. Product perception through sensory feedback is a major component in the end user product appraisal that precedes the elicitation of product emotion. Sensory evaluation is connected to a set of concepts including appraisal, concern and goal oriented objective. The i
The aim of this report is to establish recommendations for reviewing, reporting, and conducting research during the post-resuscitation period in hospital. It defines data that are needed for research and more specialised registries and therefore supplements the recently updated Utstein template for resuscitation registries. The updated Utstein template and the out-of-hospital "Chain of Survival" d
European nuthatches, Sitta europaea, live all year in permanent pair-territories. In winter, hoarded food is an important food source. To measure the rate of cache pilfering within pairs, each member of six pairs was supplied with either white- or dark-shelled sunflower seeds which the birds cached. When each bird had cached some 100-300 seeds, the feeder was removed and the birds were monitored d
