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Electrostatic interactions play an essential role in the binding of oleic acid with a-lactalbumin in the HAMLET-like complex: A study using charge-specific chemical modifications

Human a-lactalbumin made lethal to tumor cells (HAMLET) and its analogs are partially unfolded protein-oleic acid (OA) complexes that exhibit selective tumoricidal activity normally absent in the native protein itself. To understand the nature of the interaction between protein and OA moieties, charge-specific chemical modifications of lysine side chains involving citraconylation, acetylation, and

Starka styrmedel - en studie om relationen mellan arbetsgivarvarumärke och medarbetarnas organisationsidentitet

Abstract Title: Strong control mechanisms - a study of the relationship between employer brand and employee organization identity Seminar date: 2018-01-12 Course: FEKH29, Business Administration: Degree Project in Marketing, Undergraduate level, 15 University Credits Points (UPC or ECTS‐cr) Authors: Rebecca Oldfield, Mathilde Åslund Advisor: Jon Bertilsson Keywords: Organizational identity,

Konsten att kombinera tillgänglighet och exklusivitet – En dialektisk analys av spänningen mellan premium och lyx

Examensarbetets titel: Konsten att kombinera tillgänglighet och exklusivitet – En dialektisk analys av spänningen mellan premium och lyx Seminariedatum: 2025-06-05 Kurs: FEKH29, Företagsekonomi: Examensarbete i marknadsföring på kandidatnivå, 15 HP Författare: Pontus Sölve, Hannes Hemgren, Julia Johansson Mozaffari Handledare: Jon Bertilsson Fem nyckelord: Varumärke, Premium, Lyx, MasstigTitle: The art of combining availability and exclusivity – A dialectical analysis of the tension between premium and luxury Seminar date: 2025-06-05 Course: FEKH29, Business Administration: Degree Project in Marketing, Undergraduate level, 15 credits Authors: Pontus Sölve, Hannes Hemgren, Julia Johansson Mozaffari Advisor: Jon Bertilsson Key words: Brand, Premium, Luxury, Masstige, New luxu

How are brand characters portrayed in Formula 1 teams? - A Study of Experience Markets

How are brand characters portrayed in Formula 1 teams? The purpose of this study is to understand and describe brands and their brand characters within the experience market of Formula 1. We aim to contribute with conclusions regarding brand characters and their differentiation within the field of research of experience markets. The study adopts a qualitative and abductive approach, grounded in in

Lipid shape and packing are key for optimal design of pH-sensitive mRNA lipid nanoparticles

The ionizable-lipid component of RNA-containing nanoparticles controls the pH-dependent behavior necessary for an efficient delivery of the cargo - the so-called endosomal escape. However, it is still an empirical exercise to identify optimally performing lipids. Here, we study two well-known ionizable lipids, DLin-MC3-DMA and DLin-DMA using a combination of experiments, multiscale computer simula

ALK signaling primes the DNA damage response sensitizing ALK-driven neuroblastoma to therapeutic ATR inhibition

High-risk neuroblastoma (NB) is a significant clinical challenge. MYCN and Anaplastic Lymphoma Kinase (ALK), which are often involved in high-risk NB, lead to increased replication stress in cancer cells, suggesting therapeutic strategies. We previously identified an ATR (ataxia telangiectasia and Rad3-related)/ALK inhibitor (ATRi/ALKi) combination as such a strategy in two independent genetically

The perception of gonna and gotta – a study of emancipation in progress

This is an experiment the perceptual differences between full and contractedsemi-modals in English, i.e. the distinction of going to vs gonna and (HAVE) gotto vs gotta. It is a listen-and-repeat experiment and is informed by the findingsof a corpus study of the use of these forms in American English (AmE). It thusaims to integrate the social/variational and the cognitive sides of the phenomenon.

Omplaceringsrätten i det hybrida arbetslivet - En analys av arbetsgivarens omplaceringsrätt i förhållande till arbetstagarens arbetsskyldighet vid hybridarbete

Denna uppsats undersöker hur arbetsgivarens omplaceringsrätt är utformad och begränsad i svenskt rätt, samt hur den kan tillämpas vid hybridarbete. Uppsatsen redogör för hur arbetsskyldigheten som följer av avtal, lagstiftning och arbetsrättslig praxis tillsammans sätter ramarna för hur en omplacering får genomföras. De frågeställningar som ligger till grund för uppsatsen avser dels omplaceringsräThis thesis examines how the employer’s right to relocate employees is structured and limited under Swedish law and how this right may be applied in the context of hybrid work. The thesis outlines how the duty to work is based on employment contracts, legislation and case law, which collectively sets the framework within which relocation of employees may take place. The research questions underlyi

Naturally acquired antibodies against Plasmodium falciparum : Friend or foe?

Antibodies are central to acquired immunity against malaria. Plasmodium falciparum elicits antibody responses against many of its protein components, but there is also formation of antibodies against different parts of the red blood cells, in which the parasites spend most of their time. In the absence of a decisive intervention such as a vaccine, people living in malaria endemic regions largely d

Effect modification of ambient particle mortality by radon: A time series analysis in 108 U.S. cities

Numerous studies have reported a positive association between ambient fine particles and daily mortality, but little is known about the particle properties or environmental factors that may contribute to these effects. This study assessed potential modification of radon on PM2.5 (particulate matter with an aerodynamic diameter <2.5 ?m)-associated daily mortality in 108 U.S. cities using a two-stag

Axon morphology is modulated by the local environment and impacts the noninvasive investigation of its structure-function relationship

Axonal conduction velocity, which ensures efficient function of the brain network, is related to axon diameter. Noninvasive, in vivo axon diameter estimates can be made with diffusion magnetic resonance imaging, but the technique requires three-dimensional (3D) validation. Here, high-resolution, 3D synchrotron X-ray nano-holotomography images of white matter samples from the corpus callosum of a m

Introducing AI into urban studies

Innovation in artificial intelligence (AI) is transforming cities in unprecedented ways. In this chapter, we unpack the connections between AI and the urban by introducing the concept of urban AI and reflecting on its most prominent incarnations: autonomous vehicles, urban robots, city brains and urban software agents. We then illustrate how the emergence of urban AI is producing a new urbanism th

Cognitive Grammar

This entry offers a short description of the fundamental assumptions of grammar within the broad framework of Cognitive Linguistics. It presents the principles of usage-based cognitive grammar (CG), classic works in the framework, and more recent treatments of grammatical structure and content in the form of examples of grammatical notions. Central to the CG approach is the meaningful functioning

Practice lab project: a report from an autoethnographic assignment with students in higher music education

This presentation focuses on a project at an early stage of development. The aim of the practice lab project is twofold: (i) to strengthen the competence among students in higher music education with regards to the topic of practice, and (ii) contribute to research on musical practice and skill acquisition. The project is conducted at Malmö Academy of Music (Lund university). Students take part in

Plasma Alkylresorcinols is an objective biomarker for gluten intake in young children

BackgroundAlkylresorcinols are a well-established biomarker for whole grain intake. There is evidence suggesting that total plasma alkylresorcinol concentration may also be used as a biomarker for gluten intake in adults.ObjectiveThe aim of the study was to evaluate if total alkylresorcinol concentration is a valid biomarker for gluten intake in young children.MethodsNon-fasting plasma alkylresorc

Temporal quality of post-compressed pulses at large compression factors

Post-compression of ultra-short laser pulses via self-phase modulation is routinely employed for the generation of laser pulses with optical bandwidths reaching far beyond the laser gain limitations. Although high compression factors can be routinely achieved, the compressed pulses typically suffer from temporal quality degradation. We numerically and experimentally analyze the deterioration of di