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Purpose – The rate of turnover of hospital managers has been high in Sweden. Hospitals are regarded to be difficult to manage, which is connected with different discourses and action logics such as politics, medicine, care and management creating complex conditions for hospital management. The purpose of this paper is to analyse hospital managers' management conditions in conjunction with hospital

Mixed Micelles of a PEO-PPO-PEO Triblock Copolymer (P123) and a Nonionic Surfactant (C12EO6) in Water. A Dynamic and Static Light Scattering Study

The present article reports on static and dynamic light scattering (SLS and DLS) studies of aqueous solutions of the nonionic surfactant C12EO6 and the poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) triblock copolymer EO20PO68EO20 (P123) at temperatures between 25 and 45 degrees C. In water, P123 self-assembles into spherical micelles with a hydrodynamic radius of 10 nm, and at 40

Orthostatic Hypotension: Epidemiology, Prognosis, and Treatment.

Orthostatic hypotension (OH) is a common cardiovascular disorder, with or without signs of underlying neurodegenerative disease. OH is diagnosed on the basis of an orthostatic challenge and implies a persistent systolic/diastolic blood pressure decrease of at least 20/10 mm Hg upon standing. Its prevalence is age dependent, ranging from 5% in patients <50 years of age to 30% in those >70 years of

Tradable Permits in Developing Countries: Evidence From Air Pollution in Chile

Santiago was one of the first cities outside the OECD to implement a tradable permit program to control air pollution. This article looks closely at the program's performance over the past 10 years, stressing its similarities and discrepancies with trading programs implemented in developed countries and analyzing how it has reacted to regulatory adjustments and market shocks. Studying Santiago's e

Quantitative proteomics targeting classes of motif-containing peptides using immunoaffinity-based mass spectrometry.

The development of high-performance technology platforms for generating detailed protein expression profiles, or protein atlases, is essential. Recently, we presented a novel platform that we termed global proteome survey (GPS), where we combined the best features of affinity proteomics and mass spectrometry, to probe any proteome in a species independent manner while still using a limited set of

Using the resistivity method for leakage detection in a blind test at the Rossvatn embankment dam test facility in Norway

Internal erosion is a cause of embankment dam failure, thus it is important to develop methods for seepage monitoring and internal erosion detection. In order to evaluate the potential of resistivity monitoring to give an early warning of such leakage/erosion, a test was undertaken on a rockfill embankment dam with a central glacial till core at the Rossvatn test facility in Norway. Three defects,

Crisis Communication as a Multilevel Game: The Muhammad Cartoons from a Crisis Diplomacy Perspective

The Muhammad cartoon crisis in 2005 provides an illustrative example of how crises travel across geographical boundaries, in this case, from a national newspaper into a full-fledged public diplomacy crisis at the international level. From a crisis management perspective, a multilevel setting poses a real challenge to actors trying to contain the situation at hand. Likewise, the multilevel nature o

The International Proteomics Tutorial Programme (IPTP):A teaching tool box for the proteomics community.

The most critical functions of the various proteomics organisations are the training of young scientists and the dissemination of information to the general scientific community. The education committees of the Human Proteome Organisation (HUPO) and the European Proteomics Association (EuPA) together with their national counterparts are therefore launching the International Proteomics Tutorial Pro

Proteomic profiling of the signal crayfish Pacifastacus leniusculus egg and spermatophore.

Proteins of the signal crayfish Pacifastacus leniusculus egg and spermatophore were identified using in-gel digestion, mass spectrometry, and Mascot search. Forty-one and one-hundred-fifty proteins were identified in egg and spermatophore, respectively. The proteins were classified into nine categories including cell defence, cell signaling, cytoskeleton, DNA related activity, metabolism and energ

A novel multi-strain probiotic and synbiotic supplement for prevention of Clostridium difficile infection in a murine model.

The protective effect of a multi-strain probiotic and synbiotic formulation was evaluated in C57BL/6 mice infected with Clostridium difficile (CD) NAP1/027. Antibiotic treated mice were divided into four groups. Group 1, fed with a synbiotic formulation consisting of Lactobacillus plantarum F44, L. paracasei F8, Bifidobacterium breve 46, B. lactis 8:8, galacto-oligosaccharides (GOS), isomalto-olig

Immunogenic proteins of Helicobacter pullorum, Helicobacter bilis and Helicobacter hepaticus identified by two-dimensional gel electrophoresis and immunoblotting.

The ecological niches occupied by various species of Helicobacter are not yet known and the full spectrum of diseases associated with Helicobacter infections are not yet defined. Since these fastidious microaerofilic bacteria require special growth conditions new and improved molecular and serologic diagnostic methods have been developed to increase our understanding of their pathogenesis and viru

Bcl-3 and NF kappa B p50-p50 homodimers act as transcriptional repressors in tolerant CD4(+) T cells

The transcriptional events that control T cell tolerance are still poorly understood. To investigate why tolerant T cells fail to produce interleukin (IL)-2, we analyzed the regulation of NFkappaB-mediated transcription in CD4(+) T cells after tolerance induction in vivo. We demonstrate that a predominance of p50-p50 homodimers binding to the IL-2 promoter kappaB site in tolerant T cells correlate

Distinct Signatures of Chromosomal Involvement in 59 251 Translocations Across 58 Tumor Types. A Novel Perspective

Chromosomal translocations are key events in cancer, driving oncogenesis by disrupting and deregulating critical genes. While specific tumor-associated translocations are well studied, the frequencies and distributions of most remain unknown. Additionally, the role of chromosomal reshuffling in translocations has received little attention. This study presents data on the chromosomal involvement in

Do Global Inequalities Shape Marriage Market Patterns? : Rethinking Assortative Mating in Cross-National Unions

In recent years, the empirical literature on cross-national unions—marriages between migrants and members of the majority population—has experienced a shift in focus, with an increasing number of studies examining assortative mating patterns within these unions. This shift marks a significant development, indicating that the classic assimilation theory is no longer considered the sole explanation

Assessing future European lithium supply using a bottom-up approach

EVs increase demand for critical raw materials (CRMs). Many of the CRMs are mined in just a handful of countries, raising security concerns among business and policymakers. Lithium is particularly precarious due to its high geographic supply concentration, high demand growth rate and few near term substitutes. This study conducts a bottom-up assessment of European lithium extraction projects. The

The Fed Funds Rate

Syftet med uppsatsen är att med hjälp av händelsestudiemetodik undersöka om förändringar av The Federal Funds Rate ger avvikande avkastning på Stockholmsbörsen. Teorin utgörs av den effektiva marknadshypotesen, där vi utgår från den semistarka formen av marknadseffektivitet, aktiers räntekänslighet samt investerares beteende vid makroekonomiska nyheter. Undersökningen visar att det finns avvikande