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There is a growing need for selective recognition of microorganisms in complex samples due to the rapidly emerging importance of detecting them in various matrices. Most of the conventional methods used to identify microorganisms are time-consuming, laborious and expensive. In recent years, many efforts have been put forth to develop alternative methods for the detection of microorganisms. These m
Background: Prognostic factors in patients with localized primary cutaneous malignant melanoma (CMM) are well described. However, prognostic factors for recurrence are less documented. Objectives: The aim of this study was to identify prognostic risk factors for first recurrence in patients with localized stages I-II CMM using population-based data. Methods: This study included 1437 CMM patients r
Overcoming type I migration and preventing low-mass planets from spiralling into the central star is a long-studied topic. It is well known that outward migration is possible in viscously heated disks relatively close to the central star because the entropy gradient can be sufficiently steep for the positive corotation torque to overcome the negative Lindblad torque. Yet efficiently trapping plane
Microbial immunoglobulin A (IgA) proteases cleave human secretory IgA, promoting the mucosal adhesion of pathogens. To investigate if the enteric protozoan Blastocystis degrades human secretory IgA, cell lysate and conditioned medium from two species were exposed to immunoglobulin A. Secretory IgA was cleaved by both cell lysate and conditioned medium with mainly cysteine proteinase activity in B.
Introduction: Multiple myeloma (MM) is a plasma cell neoplasm with substantial morbidity and mortality. A comprehensive description of the global burden of MM is needed to help direct health policy, resource allocation, research, and patient care.Objective: To describe the burden of MM and the availability of effective therapies for 21 world regions and 195 countries and territories from 1990 to 2
Vi vill med den här artikeln peka på att Sveriges städer har flera utmaningar kring styrning och hantering av vatten, samt föreslår sju principer för lösningar. Klimatförändringarna och den urbana tillväxten gör att åtgärder behövs nu för att hantera både vattenbrist och översvämning på ett integrerat sätt. Här fokuserar vi på kommunnivå och urbana områden, där vi argumenterar för att det behövs eWe argue in this paper that Swedish urban areas have several urgent challenges when it comes to water governance and we propose seven principles for addressing them. Climate change and urban growth call for swift action to manage both water scarcity and flooding in an integrated way. This paper focuses on the municipal level for which we argue that there is a need for a more systematic approach. T
How might a liberal democratic community best regulate human genetic engineering? Relevant debates widely deploy the usually undefined term “human dignity.” Its indeterminacy in meaning and use renders it useless as a guiding principle. In this article, I reject the human genome as somehow invested with a moral status, a position I call “genetic essentialism.” I explain why a critique of genetic e
Background: Studies have shown that ambient air pollution is linked to preeclampsia (PE), possibly via generation of oxidative stress in the placenta. Telomere length and mitochondrial DNA copy number (mtDNAcn) are sensitive to oxidative stress damage.Objective: To study the association between prenatal exposure to ambient nitrogen oxides (NOx, a marker for traffic-related air pollution), and PE,
IMPORTANCE: There is a lack of agreement on what constitutes successful outcomes for the process of health care transition (HCT) among adolescent and young adults with special health care needs.OBJECTIVE: To present HCT outcomes identified by a Delphi process with an interdisciplinary group of participants.DESIGN, SETTING, AND PARTICIPANTS: A Delphi method involving 3 stages was deployed to refine
An integrated thermal biosensor array was designed and fabricated for the simultaneous determination of glucose, urea and penicillin. The sensor contains ten thin-film thermistors which were fabricated on quartz chip by micromachining and semiconductor technologies. This sensor allows to determine maximum five different analytes nearly simultaneously by serially dividing the single microchannel in
The Nehruvian policies propagated upon India’s independence envisaged no place for religion in political mobilization. Still, religion has continued to affect and influence Indian politics, even as India has become progressively affected by processes of liberalization and globalization. The particular politics of Indian secularism was based on keeping a distance from matters of faith and custom. H
This introduction presents an overview of the key concepts discussed in the subsequent chapters of this book. The book focuses on a collective of international scholars who are researching at the intersections of media, mobility and sociality. It explores the divergent vantage points of the interplay between mobilities and socialities, analysing material conditions, situated contexts and the ascri
