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Chromosomal rearrangements (e.g., fusions/fissions) have the potential to drive speciation. However, their accumulation in a population is generally viewed as unlikely, because chromosomal heterozygosity should lead to meiotic problems and aneuploid gametes. Canonical meiosis involves segregation of homologous chromosomes in meiosis I and sister chromatid segregation during meiosis II. In organism

Purpose: Endwall film cooling protects vane endwall by coolant coverage, especially at the leading edge (LE) region and vane-pressure side (PS) junction region. Strong flow impingement and complex vortexaa structures on the vane endwall cause difficulties for coolant flows to cover properly. This work aims at a full-scale arrangement of film cooling holes on the endwall which improves coolant effi

Mitochondrial dysfunction has been implicated in major depressive disorder (MDD). A measure of mitochondrial respiratory chain (RC) enzymatic activity—the Mitochondrial Health Index (MHI)—has previously been found to correlate with stress and emotional states in caregivers. We here report mitochondrial RC activities, mitochondrial DNA copy number (mtDNAcn), and the composite MHI in unmedicated and

NGC 2419 is one of the remotest star clusters in the Milky Way halo and its exact nature is yet unclear. While it has traits reminiscent of a globular cluster, its large radius and suggestions of an abundance spread have fueled the discussion about its origin in an extragalactic environment, possibly the remnant of the accretion of a dwarf galaxy. Here, we present first results from deep intermedi

Gebel el-Silsila displays an astounding concentration of incised illustrations, of which anthropomorphic figures are frequent motifs. These figures were produced over several millennia; from prehistoric petroglyphs to pictorial graffiti of dynastic periods and throughout into Roman days. Spanning over six millennia visitors to Gebel el Silsila depicted huntsmen, warriors, boatmen, and horsemen, reGebel el Silsila displays an astounding concentration of incised illustrations, of which anthropomorphic figures are frequent motifs. These figures were produced over several millennia: from prehistoric petroglyphs to pictorial graffiti of dynastic periods and throughout into Roman days. Spanning over six millennia visitors to Gebel el Silsila depicted huntsmen, warriors, boatmen, and horsemen, re

Geospatial data are increasingly available nowadays, and this leads to more analyses and visualisation of geospatial data from several sources. To enable this, we need homogenous data as well as proper integration methods. Geospatial data integration has been a longstanding research topic for decades, and this paper discusses the utilisation of Linked Data technology stack to alleviate the geospat

Organisms use circadian rhythms to anticipate and exploit daily environmental oscillations. While circadian rhythms are of clear importance for inhabitants of tropic and temperate latitudes, its role for permanent residents of the polar regions is less well understood. The high Arctic Svalbard ptarmigan shows behavioral rhythmicity in presence of light-dark cycles but is arrhythmic during the pola

Purpose - H2O, CO2 and CO are three main species in combustion systems which have high volume fractions. In addition, soot has strong absorption in the infrared band. Thus, H2O, CO2, CO and soot may take important roles in radiative heat transfer. To provide calculations with high accuracy, all of the participating media should be considered non-gray media. Thus, the purpose of this paper is to st

The lipid-protein film covering the interface of the lung alveolar in mammals is vital for proper lung function and its deficiency is related to a range of diseases. Here we present a molecular-level characterization of a clinical-grade porcine lung surfactant extract using a multitechnique approach consisting of 1H-13C solid-state nuclear magnetic spectroscopy, small-And wide-Angle X-ray scatteri

Neutrophils migrate to infected mucosal sites that they protect against invading pathogens. Their interaction with the epithelial barrier is controlled by CXC chemokines and by their receptors. This study examined the change in susceptibility to urinary tract infection (UTI) after deletion of the murine interleukin 8 receptor homologue (mIL-8Rh). Experimental UTIs in control mice stimulated an epi

I detta kapitel beskrivs hur man vid Lunds tekniska högskola organiserar kursvärderingar som en del i ett övergripande arbete med rapporterande utvärdering av kurser. Syftet är att bidra med förståelse för hur olika konkreta problem förknippade med genomförandet av ett system för kursvärdering och utvärdering angripits på Lunds tekniska högskola. kapitlet visar också på hur Lunds tekniska högskola

The prevalence of violent conflicts over the last few decades has left numerous countries in the need of thorough rebuilding; from Afghanistan to Cambodia, Sri Lanka, Guatemala, Somalia or Rwanda. In order to assist in the recovery of these post-conflict societies, various peacebuilding strategies and transitional justice mechanisms have been implemented by a range of different actors. However, mo

This essay examines the philosophical questions posed in Virginia Woolf’s famous novel Mrs Dalloway (1925) set in London in the aftermath of World War I. In her unique tone and poetic aesthetics, Woolf deals with questions about war and its aftermaths, evil and oppressive power, time and temporality, duality of life, fear of suffering and death, sacrifice and suicide but also, most importantly, lo

I denna rapport föreslås en metod som syftar till att fördjupa förståelsen för identifiering av verifieringsbehovet, som rekommenderas i de svenska byggreglerna för analytisk dimensionering av byggnadstekniskt brandskydd. Syftet med denna rapport är att ge vägledning åt ingenjörer att noggrant ta reda på vilken effekt en förändring av en byggnads utformning har på byggnadens brandskyddssystem. FöIn this report a method is proposed that aims to deepen the understanding for identification of the need for verification that is recommended in Swedish regulations for performance based design of fire safety in buildings. The purpose of this report is to provide guidance to engineers on how to thoroughly identify the effect that an alteration to a building design has on the buildings total fire s