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Inverting sustainable development? Rethinking ecology, innovation and spatial limits
Over the years, two strands of thought on Sustainable Development (SD) have emerged, often identified as ecologism and environmentalism, respectively. This paper suggests that there exists a third rhetorically excluded option, namely large-scale industrial expansion into space. Access to raw materials found on the Moon as well as unfiltered solar energy would dramatically increase the stock of res
Unveiling the Secrets of the Galactic bulge through stellar abundances in the near-IR: a VLT/Crires project
Biosynthesis, Processing, and Sorting of Human Neutrophil Granule Proteins. Focus on Cathepsin G, Proteinase 3, and Azurocidin
Popular Abstract in Swedish Bildning, bearbetning och upplagring av cathepsin G, proteinas 3 och azurocidin - närbesläktade bakteriedödande proteiner i vita blodkroppar Människans kropp utsätts dagligen för fientliga attacker av olika sorters mikroorganismer, tillhörande bakterie-, virus- eller svampsläktet. Så länge vi är friska och vårt immunförsvar fungerar, kan vi som tur är framgångsrikt föThe neutrophil granulocyte contains a number of multifunctional proteins stored in different subsets of granules. The azurophil granules, synthesized early during differentiation, harbour leukocyte elastase, cathepsin G, proteinase 3, and azurocidin; the members of the serprocidin family. In order to study the biosynthesis, processing, and intracellular sorting of the proteins, human cDNA encoding
Neural Optimization
The sermon as a listening challenge? Investigating vocabulary in contemporary English preaching.
Language history and culture groups among Austroasiatic-speaking foragers of the Malay Peninsula
The Malay Peninsula is a crossroads for people, languages and cultural influences, apparent in today's vibrant mix of Malay, Chinese, Indian, Thai and European. Yet this modern state of affairs all but conceals signals of much older situations of diversity. Thus, some 140,000 people grouped together under the label Orang Asli (Malay for 'aboriginal people') represent a range of cultural and biolog
Using SI to bridge the transition from secondary to tertiary education
Delineating the cellular pathways of hematopoietic lineage commitment.
The prevailing model for adult hematopoiesis postulates that the first lineage commitment step results in a strict separation of common myeloid and common lymphoid pathways. However, the recent identification of granulocyte/monocyte (GM)-lymphoid restricted lymphoid-primed multipotent progenitors (LMPPs) and primitive common myeloid progenitors (CMPs) within the "HSC" compartment provide compellin
Evidence for De Novo Expression of Thymic Insulin by Peripheral Bone Marrow-derived Cells.
Thymic expression of insulin has been suggested to play a major role in negative selection of autoreactive T cells and tolerance induction against pancreatic beta cells. Furthermore, the expression of insulin in peripheral antigen-presenting cells (APC) has been clearly demonstrated but whether thymic negative selection and tolerance induction also depends on peripheral influx of self-antigens (Ag
Cognitive semiotics: an emerging field for the transdisciplinary study of meaning
The article provides an overview of ongoing research and key characteristics of Cognitive Semiotics, an emerging field dedicated to the transdiciplinary study of meaning, involving above all researchers from semiotics, linguistics, developmental and comparative psychology and philosophy. The combination of the following features distinguishes it from other synthetic approaches: (a) integration of
The leucine-rich repeat protein PRELP binds fibroblast cell surface proteoglycans and enhances focal adhesion formation.
PRELP is a member of the leucine-rich repeat family of extracellular matrix proteins in connective tissue. In contrast to other members of the family, the amino-terminal domain of PRELP has a high content of proline and positively charged amino acids. This domain has previously been shown to bind chondrocytes and to inhibit osteoclast differentiation. Here we show that PRELP mediates cell adhesion
Effects of an amphiphilic graft copolymer on an oil-continuous microemulsion. Molecular self-diffusion and viscosity
Mixtures of an amphiphilic graft copolymer in water/sodium bis(2-ethylhexyl) sulfosuccinate (AOT)/cyclohexane oil-continuous microemulsions are studied by the PGSE NMR technique and by viscometry. The graft copolymer has an oil-soluble poly(dodecyl methacrylate) backbone and water-soluble poly(ethylene glycol) side chains. Water, surfactant, and polymer self-diffusion coefficients can be measured
Aggregation in a protein-surfactant system. The interplay between hydrophobic and electrostatic interactions
By precipitating a complex salt Ly(OS)(8) of the positively charged protein lysozyme and the anionic surfactant octyl sulfate OS-, one can generate a true ternary system: water-Ly(OS)(8)-NaOS. Using NMR diffusometry and U spectroscopy measurements the thermodynamic parameters of the association processes have been determined. The solubility product of the complex salt, K-s, is 10-(28) M-9.(1) On a
Competitive Na+ and Rb+ binding in the minor groove of DNA
Sequence-dependent coordination of alkali ions to the nucleotide bases in the minor groove of AT-tract B-DNA has recently been inferred from X-ray crystallography, solution NMR and computer simulations. Here, we present new Na-23 and Rb-87 magnetic relaxation dispersion (MRD) data that demonstrate competitive and long-lived binding of Na+ and Rb+ ions in the minor groove of the B-DNA duplex [d(CGC
Alternative food systems and the citizen-consumer
Ethically informed and committed consumers are crucial to the functioning of many alternative food systems. These consumers are poorly understood, though, and their common description as informed and democratically minded finds little resemblance to the real world. Few individuals fit the ideal of the concept of the so-called citizen-consumer. This commentary therefore argues that both researchers
Multi-modal visual experience of brand-specific automobile design
Purpose – This paper presents a questionnaire study of brand-specific perceptions of automotive design using subjective rating methods. The purpose of the paper is to explore the multiple modalities of the visual product experience of automobile design as perceived by the general public. Furthermore, the experiences were analysed using a framework for visual product experience (VPE). Design/method
Lack of association between chlamydophila pneumoniae seropositivity and abdominal aortic aneurysm.
Abstract is not available
Distribution of the maximum in air pollution fields
Air quality standards are set to protect public health. The values of the standards are often based on health effect studies, without any statistical considerations. In order to judge if a standard is met measurements of ambient air quality are taken at monitoring stations, and these measured values are used to decide whether or not the standard has been violated. In this paper we examine the stat
Bone-resorptive effects of endotoxin-contaminated high-density polyethylene particles spontaneously eliminated in vivo.
Wear particles commonly used for experiments may carry adherent endotoxin on their surfaces, which may be responsible for the observed effects. In this study, we attached titanium plates to the tibiae of 20 rats. After osseointegration, endotoxin-contaminated or uncontaminated high-density-polyethylene (HDPE) particles were applied. Contaminated specimens showed a dramatic resorption of bone after
