Sökresultat

Our ever-changing world has to a great extent created a need of efficient financial risk-management programs for financial institutions and corporations operating in a demanding international environment. These changes have however also increased the types of financial tools and derivatives used to handle the multifold macroeconomic exposures. Companies have therefore diversified opportunities to

What happened in Dersim in 1937–38, in the early years of the Turkish Republic, is no longer a secret. In recent decades, Dersim has been recognised as at least a state-led “massacre”, mass graves have been discovered, and written and oral testimonies of both victims and perpetrators have come to light. However, a clear definition and recognition of this genocide, as well as reconciliation and res

Background: Depression and suicidal behavior have been linked to increased blood-brain barrier (BBB) permeability. Platelet-derived growth factor receptor beta (PDGFR-β) is widely expressed in pericytes and promotes BBB integrity. Here, we investigated cerebrospinal fluid (CSF) levels of PDGFR-β in suicide attempters and healthy controls and correlated PDGFR-β to depression symptom severity. Metho

Purpose: To provide a focused review of sickle cell retinopathy in the light of recent advances in the pathogenesis, multimodal retinal imaging, management of the condition, and migration trends, which may lead to increased prevalence of the condition in the Western world. Methods: Non-systematic focused literature review. Results: Sickle retinopathy results from aggregation of abnormal hemoglobin

To improve the results of Enterprise Systems (ES) implementation projects, new or revised implementation methodologies are introduced by ES vendors. Yet, the innovation and adoption of implementation methodologies (IM), which are computer-based and incorporate both project management and functional components, can be problematic. The purpose of this paper is to describe and explain the adoption of

Purpose - H2O, CO2 and CO are three main species in combustion systems which have high volume fractions. In addition, soot has strong absorption in the infrared band. Thus, H2O, CO2, CO and soot may take important roles in radiative heat transfer. To provide calculations with high accuracy, all of the participating media should be considered non-gray media. Thus, the purpose of this paper is to st

Geospatial data are increasingly available nowadays, and this leads to more analyses and visualisation of geospatial data from several sources. To enable this, we need homogenous data as well as proper integration methods. Geospatial data integration has been a longstanding research topic for decades, and this paper discusses the utilisation of Linked Data technology stack to alleviate the geospat

Road Safety Audits (RSA) and Road Safety Inspections (RSI) are effective means of Road Infrastructure Safety Management. They are preventive tools, consisting of systematic, safety assessments, carried out by trained, independent safety expert teams, resulting in a formal report on detected road hazards and safety issues, requiring a formal response by the relevant road authority. Yet, current reg

Neutrophils migrate to infected mucosal sites that they protect against invading pathogens. Their interaction with the epithelial barrier is controlled by CXC chemokines and by their receptors. This study examined the change in susceptibility to urinary tract infection (UTI) after deletion of the murine interleukin 8 receptor homologue (mIL-8Rh). Experimental UTIs in control mice stimulated an epi

I detta kapitel beskrivs hur man vid Lunds tekniska högskola organiserar kursvärderingar som en del i ett övergripande arbete med rapporterande utvärdering av kurser. Syftet är att bidra med förståelse för hur olika konkreta problem förknippade med genomförandet av ett system för kursvärdering och utvärdering angripits på Lunds tekniska högskola. kapitlet visar också på hur Lunds tekniska högskola

In an explorative manner, this article uses a data-driven digital history set-up to focus on how the Swedish Riksdag, its political parties and parliament members discussed media issues. By distant reading and topic modeling a dataset of more than 11,000 parliamentary minutes – approximately 400 million characters – the article gives a new perspective of Swedish media history in general and nation

Chromosomal rearrangements (e.g., fusions/fissions) have the potential to drive speciation. However, their accumulation in a population is generally viewed as unlikely, because chromosomal heterozygosity should lead to meiotic problems and aneuploid gametes. Canonical meiosis involves segregation of homologous chromosomes in meiosis I and sister chromatid segregation during meiosis II. In organism

Purpose: Endwall film cooling protects vane endwall by coolant coverage, especially at the leading edge (LE) region and vane-pressure side (PS) junction region. Strong flow impingement and complex vortexaa structures on the vane endwall cause difficulties for coolant flows to cover properly. This work aims at a full-scale arrangement of film cooling holes on the endwall which improves coolant effi

Mitochondrial dysfunction has been implicated in major depressive disorder (MDD). A measure of mitochondrial respiratory chain (RC) enzymatic activity—the Mitochondrial Health Index (MHI)—has previously been found to correlate with stress and emotional states in caregivers. We here report mitochondrial RC activities, mitochondrial DNA copy number (mtDNAcn), and the composite MHI in unmedicated and

NGC 2419 is one of the remotest star clusters in the Milky Way halo and its exact nature is yet unclear. While it has traits reminiscent of a globular cluster, its large radius and suggestions of an abundance spread have fueled the discussion about its origin in an extragalactic environment, possibly the remnant of the accretion of a dwarf galaxy. Here, we present first results from deep intermedi

Infectious diseases often vary seasonally in a predictable manner, and seasonality may be responsible for geographical differences in prevalence. In temperate regions, vector-borne parasites such as malaria are expected to evolve lower virulence and a time-varying strategy to invest more in transmission when vectors are available. A previous model of seasonal variation of avian malaria described a

This chapter describes the musculoskeletal (MSK) context in children and young people as an important contributor to the global non-communicable disease burden. Through selected MSK conditions, we describe the impact on patients, families and communities and highlight the challenges that need to be addressed. We focus on opportunities for better working together and describe exemplar initiatives t