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Bacterial surface protein L binds and inactivates neutrophil proteins S100A8/A9.

Finegoldia magna is an anaerobic bacterial species that is part of the normal human flora on all nonsterile body surfaces, but it is also a significant opportunistic pathogen causing a wide range of infections. Some isolates of F. magna that are more frequently associated with clinical infection express protein L, a surface protein containing multiple homologous domains (B1-B5) that bind Igs throu

The Evolution of HIV-1 Interactions with Coreceptors and Mannose C-Type Lectin Receptors.

The phenotype of human immunodeficiency virus type 1 (HIV-1) commonly evolves between and within infected individuals, at virus transmission, and during disease progression. This evolution includes altered interactions between the virus and its coreceptors, i.e., chemokine receptors, as well as mannose C-type lectin receptors (CLRs). Transmitted/founder viruses are predominantly restricted to CCR5

IL-21 and autoimmune disease - hypothesis and reality?

Previous data have indicated that IL-21 and/or IL-21R are crucial for the differentiation of naïve T cells into Th17 cells and also play a key role in the development of autoimmune disease. Given this, IL-21 and/or IL-21R are potential targets for therapy of such diseases; however, a study in this issue of the European Journal of Immunology, provides a new twist in the story as it is now shown tha

DA rats from two colonies differ genetically and in their arthritis susceptibility.

The arthritis-susceptible DA rat is one of the most commonly used rat strains for genetic linkage analysis and is instrumental for the identification of many genetic loci. Even though DA rats were kept as inbred lines at different institutes and suppliers, it became obvious that the various breeding stocks differed genetically. To be able to compare the results from different linkage studies it is

The organization of articulator gestures: A comparison of Swedish, Bulgarian and Greenlandic.

This paper reports speech articulator gestures in Swedish, Bulgarian, and Greenlandic to study universal and language-specific components in articulation. This work is based on analysis of movements of individual articulators from x-ray motion films of speech, and continues from previous reports from this study by Wood [J. Phon. 7, 25–43 (1979); 19, 281–292 (1991); Proc. 3rd Conf. I.C.P.L.A., 191–

Johannes Tauler. Djup ropar till djup

Swedish translation (by B. Stolt) of select sermons by John Tauler (c. 1300-1361). A selection was made from among the authentic texts in Middle German.