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Doxapram for the prevention and treatment of apnea in preterm infants

Background: Apnea of prematurity is a common problem in preterm infants that may have significant consequences on their development. Methylxanthines (aminophylline, theophylline, and caffeine) are effective in the treatment of apnea of prematurity. Doxapram is used as a respiratory stimulant in cases refractory to the methylxanthine treatment. Objectives: To evaluate the benefits and harms of doxa

How smart are electricity users with ‘Smart Metering’? A Behavioural Economics experiment

The purpose of this paper is to examine how behavioural biases affect consumers’ response to energy-use information provided through smart meters (SM). We take insights from behavioural economics and carry out two real-life experiments with SMs and electricity users. The experiments were conducted in Copenhagen (Denmark) to identify and assess the potential of two economic behavioural biases, sali

The Law and the Insane: Cases of Literary Censorship Involving the Mentally Insane During the Qianlong Reign

In a study on the problems of censorship and interpretation from 1984, (Censorship and Interpretation; The Conditions of Reading and Writing in Early Modern England), Annabel Patterson states that British authors of the seventeenth century often used the shelter of ambiguity as a protection from the threat of censorship. But as the text had to be understood by the intended readers, Patterson argue

Laser-induced fluorescence imaging for studies of cultural heritage - art. no. 66180P

Laser-induced fluorescence for remote imaging of historical monuments is an established technique, which in this work has been used in measurement campaigns at the Coliseum and the Baptistery of San Giovanni in Laterano in Rome, Italy. The results presented here are examples that show that biodeteriogens can be monitored and that. materials can be identified. Also, cleaned and soiled areas on the

Processing and characterization of nanowire arrays for photodetectors

We present a fabrication scheme of contacting arrays of vertically standing nanowires (NW) for LEDs (Duan et al. Nature 409:66–69, 2001), photodetectors (Wang et al. Science (NY) 293:1455–1457, 2001) or solar cell applications (Wallentin et al. Science (NY) 339:1057–1060, 2013). Samples were prepared by depositing Au films using nano-imprint lithography (Ma rtensson et al. Nano Lett 4:699–702, 200

Second-order constraints in dynamic invariant inference

The current generation of dynamic invariant detectors often produce invariants that are inconsistent with program semantics or programmer knowledge. We improve the consistency of dynamically discovered invariants by taking into account higher-level constraints. These constraints encode knowledge about invariants, even when the invariants themselves are unknown. For instance, even though the invari

Cerebral near-infrared spectroscopy monitoring for prevention of death or neurodevelopmental disability in very preterm infants

RATIONALE: Very preterm infants (i.e. born before 32 weeks of gestation) are at risk of cerebral injury and long-term neurodevelopmental impairment. Cerebral near-infrared spectroscopy (NIRS) enables continuous monitoring of cerebral oxygenation to guide clinical management. Interest in NIRS has grown in recent years, highlighting the need for better evidence to support its clinical efficacy in im

3D DCIP techniques for detection of internal defects in the Älvkarleby test dam

This study explores the effectiveness of combining Electrical Resistivity Tomography (ERT) and Induced Polarization (IP) for identifying internal erosion processes in embankment dams. A small-scale test dam was built in Älvkarleby, Sweden, with deliberately embedded but undisclosed defects to test monitoring capabilities. Daily ERT and IP measurements were collected during 4.5-year years, and anal

CYP2D6 UM phenotype is not related to suicide attempts in depressive patients in secondary psychiatric care

Introduction: The hepatic cytochrome P450 system includes the polymorphic CYP2D6 gene. CYP2D6 ultra rapid metabolizers (UMs) were 10-fold more common in suicide victims than in the general population in a previous study. The aim of this study was to investigate if the occurrence of the CYP2D6 UM genotype differs between subjects with and without previous suicide attempt in patients treated for dep

Manual lymphatic drainage for lymphedema following breast cancer treatment

Background More than one in five patients who undergo treatment for breast cancer will develop breast cancer-related lymphedema (BCRL). BCRL can occur as a result of breast cancer surgery and/or radiation therapy. BCRL can negatively impact comfort, function, and quality of life (QoL). Manual lymphatic drainage (MLD), a type of hands-on therapy, is frequently used for BCRL and often as part of com

The chemical evolution of the Galactic Bulge seen through micro-lensing events

Galactic bulges are central to understanding galaxy formation and evolution. Here we report on recent studies using micro-lensing events to obtain spectra of high resolution and moderately high signal-to-noise ratios of dwarf stars in the Galactic bulge. Normally this is not feasible for the faint turn-off stars in the Galactic bulge, but micro-lensing offers this possibility. Elemental abundance