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A Sustainability Assessment of the Urban Rehabilitation Project of the Medina of Fez, Morocco

The old city of Fez, Morocco, classified as Heritage of Humankind by the UNESCO, is subject to an integrated rehabilitation plan running over 15 years. The plan aims at restoring and preserving the economy, cultural value, and social heritage of the old city. The study follows a system dynamics approach to describe and analyze the rehabilitation plan in order to identify the strengths and defects

In search of differentiations in the development the picture sign

The differentiation between expression and content is fundamental in the concept of signs. Even if the notions of signs are often revised, due partly to the attraction of a semiotic approach from markedly disparate objects of study, a common apprehension of the distinctive character of meanings by sign is its dual nature. (Saussure 1968, Piaget 1951, 1966; Vygotsky 1999; Sigel 1978; DeLoache 2000)

Ischemic Tolerance and Cell Signaling in the Rat Brain

Popular Abstract in Swedish Cellulära mekanismer vid ischemisk tolerans Stroke, hjärntrauma, hjärnblödning och övergående hjärtstillestånd, leder till minskat blodflöde till hjärnan (ischemi) och orsakar hjärnskador. Mot denna skadeutveckling finns ännu inte något medel för kliniskt bruk. I djurexperimentella ischemimodeller har man kunnat skydda hjärnan mot ischemiska skador genom att utsätta hjäA brief period of sublethal ischemia in the brain induces resistance to a subsequent, otherwise lethal ischemic insult. This phenomenon is known as ischemic tolerance or preconditioning. A model of ischemic preconditioning in the rat brain using the two-vessel occlusion model of global cerebral ischemia was established. Using this model we have demonstrated that ischemic preconditioning protects t

Plasma calprotectin in the emergency department : a potential clinical biomarker for patients with infectious diseases

Increased levels of plasma calprotectin are reported in patients with infectious diseases. However, the clinical usefulness of calprotectin as a biomarker to identify patients with infectious diseases in the emergency department (ED) setting has not been investigated. To study the ability of calprotectin to discriminate patients with acute infectious diseases and dyspnea from patients with other c

Doxapram for the prevention and treatment of apnea in preterm infants

Background: Apnea of prematurity is a common problem in preterm infants that may have significant consequences on their development. Methylxanthines (aminophylline, theophylline, and caffeine) are effective in the treatment of apnea of prematurity. Doxapram is used as a respiratory stimulant in cases refractory to the methylxanthine treatment. Objectives: To evaluate the benefits and harms of doxa

Why Pashukanis was right : Abstraction and form in The General Theory of Law and Marxism

The area of Marxism and law has long been considered marginalised. However, hand in hand with the renaissance of Marxist theory in recent decades, neglect has finally been put to rest. As Marxists increasingly explore the connections between rights, law, democracy and capitalism, one text in particular has taken centre stage: The General Theory of Law and Marxism, published by E. B. Pashukanis in

Tumor necrosis factor (TNF) inhibitors for juvenile idiopathic arthritis

Background: Juvenile idiopathic arthritis (JIA) is a rheumatic disorder that causes chronic joint inflammation beginning before the age of 16 years. Pharmacological treatment necessary to prevent joint destruction and functional impairment includes non-steroidal anti-inflammatory drugs (NSAIDs), intra-articular corticosteroids, conventional synthetic (cs) disease-modifying anti-rheumatic drugs (DM

Cerebral near-infrared spectroscopy monitoring for prevention of death or neurodevelopmental disability in very preterm infants

RATIONALE: Very preterm infants (i.e. born before 32 weeks of gestation) are at risk of cerebral injury and long-term neurodevelopmental impairment. Cerebral near-infrared spectroscopy (NIRS) enables continuous monitoring of cerebral oxygenation to guide clinical management. Interest in NIRS has grown in recent years, highlighting the need for better evidence to support its clinical efficacy in im