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Erythropoietin (Epo) has been used in the treatment of anemia resulting from numerous etiologies, including renal disease and cancer. However, its effects are controversial and the expression pattern of the Epo receptor (Epo-R) is debated. Using in vivo lineage tracing, we document that within the hematopoietic and mesenchymal lineage, expression of Epo-R is essentially restricted to erythroid lin

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This paper provides evidence that it is worthwhile to reconsider the traditional research circle method as a means of involving people in the third age in fulfilling their needs to participate in learning activities and make their voices heard. The findings are based on three cases of research circles consistently driven by the interests of the older participants and which increased their capacity

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BACKGROUND: Reducing side effects of immunosuppressive regimens has become a priority in transplantation medicine because of the large number of patients and grafts that succumb to infection in the short term and cardiovascular disease in the long term. The Symphony study was a 12-month prospective, randomized, open-label, multi-centre, four parallel arm study that aimed to evaluate the safety and

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Popular Abstract in Swedish Är muslimer så annorlunda jämfört med andra medborgare att de måste leva segregerade och separeras från resten av det svenska samhället? Vad är en muslim och vem skall definiera denna kategori? I den här avhandlingen presenteras huvudaktörerna i diskussionen och deras ideologiska synsätt. Den mångkulturalistiska ideologin är hegemonisk i Sverige när det gäller frågor soAre Muslims so different from other citizens in Sweden, that they have to live in segregation and be separated from the rest of society? What is a Muslim, and who is to define this category? In this thesis, the author presents the main actors in this discussion and their ideological positions. The multiculturalist ideology is hegemonic in Sweden on issues concerned with cultural diversity, and int

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Popular Abstract in Swedish Graviditetsdiabetes (GDM) definieras som nedsatt glukostolerans av varierande svårighets¬grad som upptäcks under graviditet och som oftast försvinner efter förlossning. GDM innebär ökad risk för såväl moder som barn. Kvinnor med GDM föder ofta stora barn och har ökad risk för komplikationer i samband med förlossningen. GDM-prevalensen varierar avsevärt mellan olika popuGestational diabetes mellitus (GDM) is a heterogeneous disorder that is defined as carbohydrate intolerance with onset or first recognition during pregnancy. Impaired beta-cell function and insulin resistance are the hallmarks of GDM. The overall aim of this thesis was to study the genetic and immunological risk factors that increase susceptibility to GDM. First, we investigated whether autoimmuni

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This thesis analyses the energy consumption of the Italian and Swedish residential sector during the last two decades. It has two main purposes: (1) to test the Environmental Kuznets Curve (EKC) hypothesis that stipulate a decoupling relation between environmental harm and economic growth and (2) to investigate on four factors that could explain such decoupling relation. The key factors are the ch

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This study explores the contexts in which the conflict evolved and how history was perceived, narrated and used by institutions, communities and individuals who sought to influence public opinion and policymakers. The theoretical point of departure is the concept of collective memory, defined as the totality of discourses through which a society makes sense of itself, the present and the future th

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I denna uppsats undersöks begreppet tjänst och vad som utgör en tjänst tillhörande informationssamhället samt en tjänst på transportområdet. Utredningen görs med anledning av att en spansk domare fattat beslut om att inhämta ett förhandsavgörande där EU-domstolen ska undersöka huruvida tjänsten Uber utgör en tjänst tillhörande informationssamhället eller istället utgör ren transportverksamhet. FThe main purpose of this thesis is to examine the notion of services and consider what constitutes an information society service and a service in the transport sector. In a preliminary ruling, yet to be decided by the European Court of Justice, a Spanish judge has recently queried whether the service provided by Uber should be considered an “information society service” or merely a transport serv

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Renewable energy is gaining increasing importance in the generation of power due to the finite existence of fossil fuels and concerns about climate change. As its demand grows financial interest from investors’ increases, thus it is important to find the most effective way of quantifying the risk of the renewable energy market. Furthermore as renewable energy can be viewed as an economic substitut

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The aim of this thesis is to examine how Turkey’s “proto-transition” regarding the Kurdish issue is gendered in the light of the narratives of a particular set of victims, the wives of the disappeared. The conflict between the Turkish military and the Kurdistan Workers’ Party (Partiya Karkerên Kurdistan or PKK) has been ongoing for more than three decades. During 1980s and 1990s, enforced disappea

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The aim of this qualitative study was to explore older persons' (n = 28, 75-96 years of age) experience of becoming in need of public home help, their experience of participation and of having influence on the needs assessment procedure and the decisions made about public home help. A content analysis revealed a broad overarching category, labelled: experiencing discontinuity in life as a whole -

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This paper presents a wideband CMOS power amplifier intended for cellular handset applications. The circuit exploits injection locking to achieve a power gain of 20.5dB from a single stage amplifier. The maximum output power of 29dBm, with a peak drain- and power-added-efficiency (PAE) of 66% and 64%, respectively, occurs at a center frequency of 2GHz with a 3V supply. A cross-coupled cascode topo

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Popular Abstract in Swedish Bostäder med särskild service som upplevs ge möjlighet till socialt umgänge, avskildhet och återhämtning har positiva effekter på livskvaliteten hos människor med psykisk funktionsnedsättning. Vidare visar resultaten från denna avhandling att den visuella upplevelsen av miljön och upplevelsen av hemlikhet är betydelsefulla för att etablera en stödjande atmosfär. BoendemSupported housing facilities (SHF) are among the most common housing solutions for people with severe mental illness (SMI). A poor level of physical-environment qualities and the re-creation of institutional atmospheres in these settings have been found in recent studies. The research focus in the psychiatric field has, however, largely neglected these topics and the available knowledge does not p

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Early-life health shocks can have very serious long-term consequences for those exposed to them, a fact which must be considered when parents make decisions with regards to allocating resources across their children. Here, the 1980 famine in Karamoja, Uganda is used as a natural experiment in which to test whether parental investment responses reinforce or compensate the impacts of early-life shoc

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The Fidesz government has likely had an impact on the Hungarian economy through the “nationalistic” policies implemented. The analysis in this thesis aims to calculate the extent of the economic impact of the Fidesz government on the Hungarian economy in the period 2010 till 2018. Moreover, in Hungary the regional economic inequality is significant. The second aim of the analysis is to see how the

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on the 21st of September, the CJEU delivered the judgements in DNB Banka and AVIVA, clearly stating that the cost sharing exemption cannot be relied upon by taxable persons operating in the financial and insurance sectors, due to the fact that the scope of Article 132(1)(f) is limited to exemptions in the public interest. This paper will look at the purpose and the development of Article 132(1)(f)

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Det enhetliga patentet är ett patent som föreslagits av EU som kommer att göra det möjligt för uppfinnare att skydda sina uppfinningar i samtliga medlemsstater genom att lämna in en enda patentansökan. Detta är avsett att förenkla patentansökan och minska de tillhörande kostnaderna. Det nya patentet kommer att kunna verkställas av den enhetliga patentdomstolen, som har exklusiv behörighet. DomstolThe Unitary Patent is a patent proposed by the EU that will make it possible for inventors to protect their inventions in all Member States by submitting a single patent application. This is intended to simplify the patent application procedure and mitigate the associated costs. The new patent is to be enforced under the exclusive jurisdiction of the Unified Patent Court. The Court is envisioned t

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The ICC, which was established in 2002, has come to introduce new legal norms affecting the judicial sovereignty of its member states – a fact that has become especially prominent in regard to states attempting to transition from conflict to peace. With the overarching purpose of contributing to a greater understanding of how the ICC affects and relates to peace processes, this thesis examines the