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Intact Protein Analysis at 21 Tesla and X-Ray Crystallography Define Structural Differences in Single Amino Acid Variants of Human Mitochondrial Branched-Chain Amino Acid Aminotransferase 2 (BCAT2)

Structural technologies are an essential component in the design of precision therapeutics. Precision medicine entails the development of therapeutics directed toward a designated target protein, with the goal to deliver the right drug to the right patient at the right time. In the field of oncology, protein structural variants are often associated with oncogenic potential. In a previous proteogen

Occupation-focused health promotion for well older people-A cost-effectiveness analysis

Introduction: The aim of this study was to evaluate three occupational therapy interventions, focused on supporting continued engagement in occupation among older people, to determine which intervention was most cost effective, evaluated as the incremental cost/quality adjusted life year gained. Method: The study was based on an exploratory randomized controlled trial. Participants were 77-82 year

Hospital costs and health-related quality of life from complications after esophagectomy

Background: Approximately 50% of all patients undergoing esophagectomy experience complications. This paper estimates the costs due to complications after esophagectomy in a Swedish context. Material and methods: The Swedish National Register for Esophageal and Gastric Cancer (NREV) and the Healthcare Consumption Register in Region Skåne (RSVD) were crossmatched for patients undergoing esophagecto

Influence of awareness and availability of medical alternatives on parents seeking paediatric emergency care

Aims: Direct seeking of care at paediatric emergency departments may result from an inadequate awareness or a short supply of medical alternatives. We therefore evaluated the care-seeking patterns, availability of medical options and initial medical assessments – with overall reference to socioeconomic status – of parents at an urban paediatric emergency department in a Scandinavian country provid

The development of voluntary private health Insurance in the Nordic countries

The Nordic countries represent an institutional setting with tax-based health care financing and universal access to health care services. Very few health care services are excluded from what are offered within the publically financed health care system. User fees are often non-existing or low and capped. Nevertheless, the markets for voluntary private health insurance (VPHI) have been rapidly exp

We need implicit measures of alexithymia

Much psychological research makes use of explicit measures (e.g., questionnaires), where the participants are asked to report about themselves. Such measures at best index various aspects of the person’s conscious self-concept. However, there are also implicit measures that are designed to tap similar constructs in a more indirect way (e.g., the Implicit Association Test and the Thematic Appercept

Impact of Non-Stationary Noise on xDSL Systems: an Experimental Analysis

Broadband services require data rates that can only be achieved by using relatively high spectrum frequencies. At such high frequencies, the DSL (Digital Subscriber Line) signal is more susceptible to external noise sources, such as radio frequency interference and impulsive noise. This paper aims to characterize how the impulsive noise impacts on services and applications for a broadband system u

Changes in the unconscious processing of emotional information in panic patients after cognitive-behaviour therapy

Patients with anxiety disorders automatically attend to threat-related stimuli. This is seen not only in an attentional bias for consciously available stimuli, but also in effects of subliminally exposed (i.e., masked) stimuli. The effects of treatment on cognitive biases have been examined in a variety of anxiety disorders, and the results commonly indicate that attentional biases disappear as a

Bariatric Surgery can Lead to Net Cost Savings to Health Care Systems: Results from a Comprehensive European Decision Analytic Model

The objective of the present study was to evaluate the cost-utility of bariatric surgery in a lifetime horizon from a Swedish health care payer perspective. A decision analytic model using the Markov process was developed covering cardiovascular diseases, type 2 diabetes, and surgical complications. Clinical effectiveness and safety were based on the literature and data from the Scandinavian Obesi

Real-world cost-effectiveness in chronic myeloid leukemia: the price of success during four decades of development from non-targeted treatment to imatinib

Imatinib has revolutionized the treatment of chronic myeloid leukemia (CML). We evaluated clinical outcome and cost-effectiveness, using Swedish registry data based on patients with CML diagnosed 1973-2008. Outcome from three time periods (I: 1973-1979; II: 1991-1997; III: 2002-2008) associated with symptomatic treatment, interferon-alpha/stem cell transplant and implementation of imatinib, respec

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Abstract in Danish Kapitlet sætter fokus på, hvordan sygeplejestuderende kan udvikle professionelle kompetencer i den kliniske del af sygeplejerskeuddannelsen. Indledningsvis reflekteres over kompetencebegrebet knyttet til professionsbacheloruddannelsen, og begrebet læring defineres som henholdsvis erhvervelse og deltagelse. Erhvervelse som læringstilgang er den mest dominerende forståelse af læri

The art of gate-crashing bringing HRI into users' homes

Special purpose service robots have already entered the market and their users homes. Also the idea of the general purpose service robot or personal robot companion is increasingly discussed and investigated. To probe human-robot interaction with a mobile robot in arbitrary domestic settings, we conducted a study in eight different homes. Based on previous results from laboratory studies we identi

Engineering Design Integration & Non-Destructive Testing for the ESS accelerator

The ESS linac is under construction by the ESS partner institutes (socalled In-Kind Contributors - IKC) and will operate the most powerful proton beam ever for neutron spallation source. The linac delivers 5 MW via 2 GeV protons at a repetition rate of 14 Hz at the He-cooled solid tungsten target. The pulsed neutrons, result of the spallation, will reach the science instruments after having been m

Utlysning av stipendier från Anders Althins stiftelse 2025

Utlysning av stipendier från Anders Althins stiftelse 2025 Utlysning av stipendier från Anders Althins stiftelse 2025 Publicerad den 25 februari 2025 Sedan 1987 har Anders Althins Stiftelse delat ut stipendier till minne av docent Carl-Axel Althins arkeologiska forskning som skedde mellan åren 1939-1954. Stipendierna tilldelas främst forskare inom ämnena arkeologi, historisk arkeologi, osteologi o

https://www.ark.lu.se/article/utlysning-av-stipendier-fraan-anders-althins-stiftelse-2025/ - 2026-05-09