Filtyp
Activation of the beta-receptor for platelet-derived growth factor (PDGF) by its ligand leads to autophosphorylation on a number of tyrosine residues. Here we show that Tyr763 in the kinase insert region is a novel autophosphorylation site, which after phosphorylation binds the protein tyrosine phosphatase SHP-2. SHP-2 has also previously been shown to bind to phosphorylated Tyr1009 in the PDGF be
At the fifth session of the United Nations (UN) Environment Assembly in March 2022, UN member states were mandated to negotiate an international, legally binding instrument on plastic pollution. This article assesses pre-session submissions from the second and third negotiation rounds to identify proposed measures and priorities for the treaty. The analysis, employing systematic qualitative conten
The inclusion of the knowledge and perspectives of Indigenous peoples and local communities (IPLC) in global sciencepolicy processes are increasingly being mandated. This is indicative of the recognition of their expertise and worldviews to inform social and ecological decisions. The IPBES Values Assessment (VA) explicitly highlighted the necessity for a nuanced engagement of different actors whil
Ecologists have long proposed that environments providing more energy can support more species, yet empirical evidence frequently contradicts this expectation. We argue that such inconsistencies result from confounding geographical influences that mask the true relationship between species richness and energy-related factors. Here, by comparing species richness across different climate conditions,
Membrane technology has revolutionized protein recovery in the food industry, beginning with whey protein extraction via ultrafiltration. This success led to its application in concentrating animal proteins like blood plasma, fish proteins, and albumen. As the protein shift towards plant-based sources grows, membrane processes now enable the industrial recovery of wheat, sunflower, and rapeseed pr
Eight compounds were isolated from the water-soluble fraction of Wikstroemia indica (L.) C.A. Mey., including two new neolignans (isonitidanin-4-O-β-D-glucoside (3) and threo-citrusin B (6)), four known neolignans (1, 2, 4, and 5), along with two previously reported lignans (7 and 8). Spectral analysis (1D, 2D NMR, and HR-ESI-MS/MS) was used to identify their chemical structures. Except for compou
Bees are essential pollinators of many crops and wild plants, and pesticide exposure is one of the key environmental stressors affecting their health in anthropogenically modified landscapes. Until recently, almost all information on routes and impacts of pesticide exposure came from honey bees, at least partially because they were the only model species required for environmental risk assessments
Advances the method of isnād-cum-matn analysis for unravelling complex aspects of early Islamic history • Establishes the earliest dating of the Qurʾanic codex based on the study of hadith • Contributes to the textual history of the Qur’an • Examines the claims regarding the integrity of the text of the Qur’an • Uses case studies of the verses on stoning and breastfeeding, making it relevant to co
Tackling biodiversity loss requires not only scaling up financial resources but also improving the governance of how such resources are mobilized, allocated, and accounted for. This paper reviews recent peer-reviewed literature (2019–2023) on biodiversity finance governance, focusing on three interrelated themes: financial instruments and mechanisms, governance structures, and critical and normati
The 2018 Andalusian elections marked a watershed moment in Spain's democracy. Against all forecasts, Vox, founded in 2013 by disgruntled cadres of the Popular Party, the country's main conservative party, garnered 10 percent of the vote, thus becoming the first far-right party to enter a regional parliament and ushering in a new era in Spanish politics. Vox's meteoric rise culminated in the 2020 S
Globally, freshwater ecosystems are threatened by multiple stressors, yet our knowledge of how they interact to affect food web structure remains scant. To address this knowledge gap, we conducted a large-scale mesocosm experiment to quantify the single and combined effects of three common anthropogenic stressors: warming, increased nutrient loading, and insecticide pollution, on the network struc
The presence of a criminal underworld is one of the characteristics of a metropolis. A city unplagued by an underworld, without its share of confidence tricksters and swindlers, burglars and pick-pockets, gambling dens and houses of ill-repute, would probably not be generally counted as a great city. This is certainly true today, and it was also true four hundred years ago, and even earlier. Peki
